Acute Inflammatory Response to Low-, Moderate-, and High-Load Resistance Exercise in Women With Breast Cancer-Related Lymphedema
Conclusions. The magnitude of acute exercise-induced inflammation following upper-body resistance exercise in women with BCRL does not vary between resistance exercise loads. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Cormie, P., Singh, B., Hayes, S., Peake, J. M., Galvao, D. A., Taaffe, D. R., Spry, N., Nosaka, K., Cornish, B., Schmitz, K. H., Newton, R. U. Tags: Articles Source Type: research
Chinese Herbal Medicine and Fluorouracil-Based Chemotherapy for Colorectal Cancer: A Quality-Adjusted Meta-Analysis of Randomized Controlled Trials
Conclusions. In the present analysis, involving 36 studies, 2593 patients, 20 outcomes, 36 medical institutions, and 271 named research authors, 92% of the data points were from studies at high ROB. Given the poor quality of the data in studies identified, it cannot be concluded whether combining Chinese herbs with chemotherapy reduces toxicity of chemotherapy. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: McCulloch, M., Ly, H., Broffman, M., See, C., Clemons, J., Chang, R. Tags: Articles Source Type: research
Development of an Individualized Yoga Intervention to Address Fatigue in Hospitalized Children Undergoing Intensive Chemotherapy
Conclusion. We created a standardized yoga program and an approach to monitoring that are now ready for incorporation in clinical trials. Future work should include the adaptation of the program to different pediatric populations and clinical settings. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Diorio, C., Celis Ekstrand, A., Hesser, T., OSullivan, C., Lee, M., Schechter, T., Sung, L. Tags: Articles Source Type: research
Yoga Intervention for Patients With Prostate Cancer Undergoing External Beam Radiation Therapy: A Pilot Feasibility Study
Conclusions. A structured yoga intervention of twice-weekly classes is feasible for PC patients during a 6- to 9-week course of outpatient radiotherapy. Preliminary results are promising, showing stable measurements in fatigue, sexual health, UI, and general QOL. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Ben-Josef, A. M., Wileyto, E. P., Chen, J., Vapiwala, N. Tags: Articles Source Type: research
YOCAS(C)(R) Yoga Reduces Self-reported Memory Difficulty in Cancer Survivors in a Nationwide Randomized Clinical Trial: Investigating Relationships Between Memory and Sleep
Conclusions. In this large nationwide trial, YOCAS©® yoga significantly reduced patient-reported memory difficulty in cancer survivors. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Janelsins, M. C., Peppone, L. J., Heckler, C. E., Kesler, S. R., Sprod, L. K., Atkins, J., Melnik, M., Kamen, C., Giguere, J., Messino, M. J., Mohile, S. G., Mustian, K. M. Tags: Articles Source Type: research
Examining Mediators and Moderators of Yoga for Women With Breast Cancer Undergoing Radiotherapy
Conclusion. Yoga may provide the greatest mental-health–related QOL benefits for those experiencing pre-radiotherapy sleep disturbance and depressive symptoms. Yoga may improve physical-health–related QOL by increasing ability to find benefit in the cancer experience. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Ratcliff, C. G., Milbury, K., Chandwani, K. D., Chaoul, A., Perkins, G., Nagarathna, R., Haddad, R., Nagendra, H. R., Raghuram, N. V., Spelman, A., Arun, B., Wei, Q., Cohen, L. Tags: Articles Source Type: research
Anti-Estrogen Withdrawal Effect With Raloxifene? A Case Report
A 66-year-old patient presented with acute recurrent metastatic estrogen and progesterone receptor–positive, Her-2/neu-negative breast cancer, bone lesions (lumbar spine, pelvis), pulmonary nodules, hepatic metastasis, elevated cancer antigen 15 and liver enzymes, dyspepsia, and diarrhea. The patient had been taking raloxifene for approximately 8 years. After discontinuation, clinical parameters and symptoms improved rapidly without oncological therapy or other forms of treatment. Three months after raloxifene discontinuation, capecitabine was initiated by the treating oncologist who deemed an anti-estrogen withdrawa...
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Lemmo, W. Tags: Case Study Source Type: research
A Raloxifene Withdrawal Response: Translational Research, Definitions, and Clinical Applications
(Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Jordan, V. C. Tags: Editorials Source Type: research
In This Issue: Antiestrogen Withdrawal, Yoga, and a Reflection on Quality of Clinical Trials
(Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 1, 2016 Category: Cancer & Oncology Authors: Block, K. I. Tags: Editorials Source Type: research
Antihepatocellular Carcinoma Potential of Tetramethylpyrazine Induces Cell Cycle Modulation and Mitochondrial-Dependent Apoptosis: Regulation of p53 Signaling Pathway in HepG2 Cells In Vitro
Tetramethylpyrazine (TMP) was originally isolated from a traditional Chinese herbal medicine, Ligusticum chuanxiong. In the present study, TMP exhibits potent antitumor activities in vitro. However, the molecular mechanisms remain to be defined. Hence, this study aims to investigate the antiproliferative and apoptotic effects of TMP on HepG2 and elucidate the underlying mechanisms. Analyses using Cell Counting Kit-8 and real-time cell analyzer indicated that TMP significantly inhibited HepG2 cell proliferation. We also observed that TMP induced cell cycle arrest at the G0/G1 checkpoint and apoptosis, using flow cytometry a...
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Bi, L., Yan, X., Chen, W., Gao, J., Qian, L., Qiu, S. Tags: Articles Source Type: research
Curcumol Suppresses Breast Cancer Cell Metastasis by Inhibiting MMP-9 Via JNK1/2 and Akt-Dependent NF-{kappa}B Signaling Pathways
This study is to investigate the inhibitory effect of curcumol on breast cancer cell metastasis and elucidate the underlying molecular mechanisms. Our results showed that noncytotoxicity was caused by curcumol within 10 to 40 µg/mL in MDA-MB-231 and 4T1 cells for 24 hours, whereas sustained treatment with curcumol for 14 days significantly suppressed the clonogenic activity of cells. Importantly, curcumol at noncytotoxic concentrations suppressed the migration ability of both MDA-MB-231 and 4T1 cells. Moreover, curcumol suppressed the migration and invasion of MDA-MB-231 cells in the Boyden chamber migration and inva...
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Ning, L., Ma, H., Jiang, Z., Chen, L., Li, L., Chen, Q., Qi, H. Tags: Articles Source Type: research
Curculigo orchioides Gaertn Effectively Ameliorates the Uro- and Nephrotoxicities Induced by Cyclophosphamide Administration in Experimental Animals
Conclusion. Curculigo orchioides was found to be effective against the CPA-induced bladder and renal toxicities by its antioxidant capability and also by regulating the pro-inflammatory cytokine levels. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Murali, V. P., Kuttan, G. Tags: Articles Source Type: research
Effects of High Doses of Vitamin C on Cancer Patients in Singapore: Nine Cases
Conclusion. Randomized trials of IVC therapy are recommended because it has minimal side effects and has shown promising results. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Raymond, Y. C. F., Glenda, C. S. L., Meng, L. K. Tags: Case Studies Source Type: research
Exercise Improves Physical Function and Mental Health of Brain Cancer Survivors: Two Exploratory Case Studies
Conclusion. These findings provide initial evidence that, despite the difficulties associated with brain cancer treatment and survivorship, exercise may be safe and beneficial and should be considered in the overall management of patients with brain cancer. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Levin, G. T., Greenwood, K. M., Singh, F., Tsoi, D., Newton, R. U. Tags: Case Studies Source Type: research
Addition of Rice Bran Arabinoxylan to Curcumin Therapy May Be of Benefit to Patients With Early-Stage B-Cell Lymphoid Malignancies (Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma, or Stage 0/1 Chronic Lymphocytic Leukemia): A Preliminary Clinical Study
Conclusion. Addition of Ribraxx to curcumin therapy may be of benefit to patients with early-stage B-cell lymphoid malignancies. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - May 12, 2016 Category: Cancer & Oncology Authors: Golombick, T., Diamond, T. H., Manoharan, A., Ramakrishna, R. Tags: Articles Source Type: research
