Management of diabetic foot disease in Eastern India
ConclusionEarly hospitalization, effective glycaemic control, aggressive debridements and patient education in foot care can minimize foot diseases [1]. Grading the lesion according to Wagner ’s classification helps to plan the management. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

In memoriam
(Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Novel therapeutic protocol in the research of breast cancer treatment - Targeting the border
AbstractThe complex signaling pathways and interactions inside and among cells which are responsible for the appearance and evolving of malignancy have a distinct and well separated border, the translation process, where the signals of a mutant and dysregulating genome are becoming specific proteins evolving to the malignant phenotype. We selected as translation target the Fragile X –Mental Retardation Protein (FMRP) of the breast cancer cell, a protein of whose role in translation has not clearly elucidated yet. Triple negative breast cancer cell lines (BCCL)-(BT20, MDA-MB-231, Hs578 T) were transfected by plasmid with ...
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

A huge retroperitoneal liposarcoma
ConclusionThe management of retroperitoneal sarcomas consists of complete resection of the tumour, followed by adjuvant radiotherapy, reduces local recurrence but does not affect overall survival, and, combined with surveillance for early detection of recurrence or metastases, in our case.therapeutic embolization, proved to be useful preoperatively, allowing tumour shrinkage, and reduced blood loss during resection. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Comparative study of wound healing in primary versus delayed primary closure in contaminated abdominal surgery
ConclusionDelayed primary closure is better strategy for management of contaminated abdominal wound.it reduces the wound infection rate and length of hospital stay. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Case report of a young female with early presentation of spontaneous splenic rupture in infectious mononucleosis
AbstractSpontaneous splenic rupture is a well known, yet very rare complication of infectious mononucleosis with an estimated incidence of 0.06% to 0.5%. It primarily affects teenagers and young adults and is the leading cause of death in infectious mononucleosis. There is a 9% mortality rate associated with spontaneous splenic ruptures; in all lethal cases a rupture occurs within the first 10 days of symptoms onset from infectious mononucleosis. The present case report concerns a young female, who presented with abdominal pain, vomiting and positive Kehr ’s sign two days after the onset of infectious mononucleosis sympt...
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Gangrenous toes
(Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

In memoriam
(Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Unusual organ in chest cavity
(Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - August 31, 2016 Category: Surgery Source Type: research

Aromatase inhibitors: A comprehensive review in mechanisms of action, side effects and treatment in postmenopausal early breast cancer patients
AbstractThe best adjuvant treatment for hormone receptor-positive breast cancer, especially in the postmenopausal population, is not an unexceptionable decision and depends on several and many times unequal parameters. Apart from the mechanisms of action which are more or less the same among different agents, the two major factors for consideration are the potential side effects and treatment benefits of the selected drug. The last fifteen years have clearly shown that aromatase inhibitors (AIs) are significantly more effective than tamoxifen in preventing recurrence in this group of patients, but they seem to have no bene...
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research

Rectourethral fistula: A challenging management problem
ConclusionRectourethral fistula represents a complex management problem for any surgeon. Surgical treatment of RUF is technically demanding and requires collaboration with rectal surgeons. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research

Evaluation of intracorporeal knotting and endoloop closure in laparoscopic appendicectomy
ConclusionIn our study, both the intracorporeal knotting and endoloop closure technique were safe, successful and feasible. We concluded that if the patient cannot afford the harmonic-like material, silk could be used for the base of the appendix. Hence, in rural locations or where instruments are not affordable to the surgeon, or in financially compromised patients, silk can be used without any complication. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research

Gastric outlet and duodenal/ileal obstruction due to gastric phytobezoar
AbstractWe herein present the case of an 83-year-old man, ASA status III, with a fragmented gastric phytobezoar causing obstruction in different parts of the gastrointestinal tract. The initial mass was obviously in the stomach, and due to continuing coughing and vomiting the bezoar was fragmented. The apex of the bezoar moved through the deformed pyloric channel, temporarily occluding first the duodenojejunal flexure and afterwards the ileus, while the larger remnants repeatedly sealed off causing gastric outlet obstruction. At emergent laparotomy, a gastrojejunostomy was created through which both bezoars were extracted,...
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research

Pancreaticoduodenectomy in advanced cholangiocarcinoma
We present the case report of a 42-year-old woman with advanced perihilar carcinoma. She was admitted with obstructive jaundice and high bilirubin levels. A pancreaticoduodenectomy was performed. Given that a tumour at advanced stage requires duodenal and common bile duct resection, pancreaticoduodenectomy seemed to be the optimal solution. We believe that pancreaticoduodenectomy not only offers the necessary anastomoses but also the radicality. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research

A typical case of a widespread metastatic breast carcinoma
We present herein a case of carcinoma breast in a 55-year-old female presenting initially with skin lesions on the chest wall. Further evaluation identified a bilateral breast mass with axillary metastasis and multiple nodules over the trunk and right thigh. There was also evidence of metastasis to the lungs, bilateral adrenals and mesenteric lymph nodes. FNAC of all the nodules revealed infiltrating duct carcinoma of the breast which was confirmed by excision biopsy. (Source: Hellenic Journal of Surgery)
Source: Hellenic Journal of Surgery - June 30, 2016 Category: Surgery Source Type: research