Helicobacter pylori infection is an independent risk factor of early and advanced colorectal neoplasm
ConclusionsIn a large‐scale study, carefully controlled for confounding factors, involving asymptomatic participants without a history of colonoscopy, H. pylori infection was significantly associated with the risk of any colorectal adenoma and advanced colorectal neoplasm. Prospective studies are necessary to determine whether H. pylori eradication can reduce this risk. (Source: Helicobacter)
Source: Helicobacter - January 25, 2017 Category: Gastroenterology Authors: Tae Jun Kim, Eun Ran Kim, Dong Kyung Chang, Young ‐Ho Kim, Sun‐Young Baek, Kyunga Kim, Sung Noh Hong Tags: ORIGINAL ARTICLE Source Type: research
Autophagy ‐related genes in Helicobacter pylori infection
ConclusionsAutophagy‐related gene expression profiling using high‐throughput microarray analysis indicated that downregulation of core autophagy machinery genes may depress autophagy functions and possibly provide a better intracellular habit for H. pylori in gastric epithelial cells. (Source: Helicobacter)
Source: Helicobacter - January 23, 2017 Category: Gastroenterology Authors: Shingo Tanaka, Hiroyuki Nagashima, Takahiro Uotani, David Y. Graham, Yoshio Yamaoka Tags: ORIGINAL ARTICLE Source Type: research
Vonoprazan improves the efficacy of Helicobacter pylori eradication therapy with a regimen consisting of clarithromycin and metronidazole in patients allergic to penicillin
ConclusionFor first eradication in patients allergic to penicillin, a 7‐day triple therapy consisting of clarithromycin, metronidazole and vonoprazan could be a candidate eradication regimen. (Source: Helicobacter)
Source: Helicobacter - January 18, 2017 Category: Gastroenterology Authors: Shoko Ono, Mototsugu Kato, Soichi Nakagawa, Katsuhiro Mabe, Naoya Sakamoto Tags: ORIGINAL ARTICLE Source Type: research
Contemporary migration patterns in the prevalence of Helicobacter pylori infection: A systematic review
ConclusionsOur study findings are consistent with what would be expected based on the prevalence of H. pylori worldwide. The results of this review show that migrants are particularly at risk of infection and help to identify gaps in the knowledge of migrants' prevalence of infection globally. (Source: Helicobacter)
Source: Helicobacter - January 17, 2017 Category: Gastroenterology Authors: Samantha Morais, Ana Rute Costa, Ana Ferro, Nuno Lunet, B árbara Peleteiro Tags: REVIEW ARTICLE Source Type: research
Antibiotic resistance of Helicobacter pylori in Chinese children: A multicenter retrospective study over 7 years
ConclusionsThe resistance rates of H. pylori in children from southeast coastal region of China were very high to metronidazole, moderate to clarithromycin and levofloxacin, and low to amoxicillin and furazolidone. It is important to continue monitoring the resistance profiles of H. pylori isolated in this region. (Source: Helicobacter)
Source: Helicobacter - January 17, 2017 Category: Gastroenterology Authors: Lan Li, Yini Ke, Chaohui Yu, Guogang Li, Ningmin Yang, Jianzhong Zhang, Youming Li Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Helicobacter)
Source: Helicobacter - January 9, 2017 Category: Gastroenterology Tags: Issue Information Source Type: research
The influence of Helicobacter pylori on the ethnic distribution of esophageal eosinophilia
ConclusionEsophageal eosinophilia prevalence markedly varies by patient ethnicity. As there is a strong inverse correlation between H. pylori and esophageal eosinophilia, H. pylori infection may be in part responsible for the observed ethnic distribution of esophageal eosinophilia. (Source: Helicobacter)
Source: Helicobacter - December 27, 2016 Category: Gastroenterology Authors: Amnon Sonnenberg, Evan S. Dellon, Kevin O. Turner, Robert M. Genta Tags: ORIGINAL ARTICLE Source Type: research
Consensus on the clinical management, screening ‐to‐treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale
ConclusionsThis consensus statement has updated recommendations for improving the clinical management of H. pylori infection in areas such as Taiwan, which have high prevalence of H. pylori infection and gastric cancer. (Source: Helicobacter)
Source: Helicobacter - November 30, 2016 Category: Gastroenterology Authors: Bor ‐Shyang Sheu, Ming‐Shiang Wu, Cheng‐Tang Chiu, Jing‐Chuan Lo, Deng‐Chyang Wu, Jyh‐Ming Liou, Chun‐Ying Wu, Hsiu‐Chi Cheng, Yi‐Chia Lee, Ping‐I Hsu, Chun‐Chao Chang, Wei‐Lun Chang, Jaw‐Town Lin Tags: ORIGINAL ARTICLE Source Type: research
A novel isolation protocol and probe ‐based RT‐PCR for diagnosis of gastric infections with the zoonotic pathogen Helicobacter suis
ConclusionThe methods described above can be implemented for detection or isolation of H. suis from human gastric biopsies. (Source: Helicobacter)
Source: Helicobacter - November 30, 2016 Category: Gastroenterology Authors: Caroline Blaecher, Eva Bauwens, Alfred Tay, Fanny Peters, Sylvia Dobbs, John Dobbs, Andr é Charlett, Richard Ducatelle, Freddy Haesebrouck, Annemieke Smet Tags: Original Article Source Type: research
The importance of TH22 and TC22 cells in the pathogenesis of Helicobacter pylori ‐associated gastric diseases
ConclusionIncreased Th22, Tc22, and Tc22/17 cells and IL‐22 levels appear to be influential in progression and severity of H. pylori infection. Th22/17 can be an interesting therapeutic target for chronic H. pylori infections where eradication is more difficult. (Source: Helicobacter)
Source: Helicobacter - November 30, 2016 Category: Gastroenterology Authors: Seyedeh Azra Shamsdin, Abdolvahab Alborzi, Manoochehr Rasouli, Abbas Ghaderi, Kamran B. Lankrani, Seyed Mohsen Dehghani, Gholam reza Pouladfar Tags: Original Article Source Type: research
CCR2 mediates Helicobacter pylori ‐induced immune tolerance and contributes to mucosal homeostasis
ConclusionsOur results indicate that CCR2 plays an essential role in H. pylori‐induced immune tolerance and shed light on a novel mechanism of CCR2‐dependent DC Treg induction, which appears to be important in maintaining mucosal homeostasis during H. pylori infection. (Source: Helicobacter)
Source: Helicobacter - November 30, 2016 Category: Gastroenterology Authors: Xia Sun, Min Zhang, Mohamad El ‐Zaatari, Gray B. Huffnagle, John Y. Kao Tags: Original Article Source Type: research
High antibiotic resistance of Helicobacter pylori and its effect on tailored and empiric eradication of the organism in Lower Silesia, Poland
ConclusionsAntibiotic resistance is notably high in Poland currently, but both tailored and empiric therapies can achieve acceptable cure rates equal to or higher than 90%. (Source: Helicobacter)
Source: Helicobacter - November 23, 2016 Category: Gastroenterology Authors: Stanis ław Ferenc, Jan Gnus, Magdalena Kościelna, Małgorzata Kinda, Andriy Yarka, Luke Stewart, Wojciech Witkiewicz Tags: Original Article Source Type: research
Issue Information
(Source: Helicobacter)
Source: Helicobacter - November 14, 2016 Category: Gastroenterology Tags: Issue Information Source Type: research
Helicobacter pylori colonization and pregnancies complicated by preeclampsia, spontaneous prematurity, and small for gestational age birth
ConclusionsOur data suggest that H. pylori colonization may be a risk factor for PE and SGA. If these associations are confirmed by future studies and shown to be causal, H. pylori eradication may reduce related perinatal morbidity and mortality. (Source: Helicobacter)
Source: Helicobacter - September 30, 2016 Category: Gastroenterology Authors: Wouter J. Hollander, Sarah Schalekamp ‐Timmermans, I. Lisanne Holster, Vincent W. Jaddoe, Albert Hofman, Henriëtte A. Moll, Guillermo I. Perez‐Perez, Martin J. Blaser, Eric A. P. Steegers, Ernst J. Kuipers Tags: Original Article Source Type: research
Helicobacter pylori infection and its related factors in junior high school students in Nagano Prefecture, Japan
ConclusionsThe prevalence of H. pylori infection is as low as 3% among junior high school students aged 12‐15 years in Japan. The disappearance of H. pylori is accelerating in Japanese children. (Source: Helicobacter)
Source: Helicobacter - September 30, 2016 Category: Gastroenterology Authors: Yoshiko Nakayama, Yingsong Lin, Minoru Hongo, Hiroya Hidaka, Shogo Kikuchi Tags: Original Article Source Type: research
