CCR2 mediates Helicobacter pylori ‐induced immune tolerance and contributes to mucosal homeostasis

ConclusionsOur results indicate that CCR2 plays an essential role in H. pylori‐induced immune tolerance and shed light on a novel mechanism of CCR2‐dependent DC Treg induction, which appears to be important in maintaining mucosal homeostasis during H. pylori infection.

Source: Helicobacter - November 30, 2016 Category: Gastroenterology Authors: Xia Sun, Min Zhang, Mohamad El ‐Zaatari, Gray B. Huffnagle, John Y. Kao Tags: Original Article Source Type: research