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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - March 9, 2018 Category: Genetics & Stem Cells Source Type: research
Phosphorylation of N ‐terminal regions of REV‐ERBs regulates their intracellular localization
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - March 6, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - March 6, 2018 Category: Genetics & Stem Cells Source Type: research
The force ‐sensing device region of α‐catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Mechanotransduction by α‐catenin facilitates the force‐dependent development of adherens junctions (AJs) by recruiting vinculin to reinforce actin anchoring of AJs. The α‐catenin mechanotransducing action is facilitated by its force‐sensing device region that autoinhibits the vinculin‐binding site 1 (VBS1). Here, we report the high‐resolution structure of the force‐sensing device region of α‐catenin, which shows the autoinhibited form comprised of helix bundles E, F and G. The cryptic VBS1 is embedded into helix bundle E stabilized by direct interactions with the autoinhibitory region forming helix bundl...
Source: Genes to Cells - March 1, 2018 Category: Genetics & Stem Cells Authors: Yoshinori Hirano, Yu Amano, Shigenobu Yonemura, Toshio Hakoshima Tags: ORIGINAL ARTICLE Source Type: research
The periplasmic disordered domain of RodZ promotes its self ‐interaction in Escherichia coli
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - February 26, 2018 Category: Genetics & Stem Cells Source Type: research
Transgenic mouse lines expressing the 3xFLAG ‐dCas9 protein for enChIP analysis
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - February 26, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - February 26, 2018 Category: Genetics & Stem Cells Source Type: research
Transgenic mouse lines expressing the 3xFLAG ‐dCas9 protein for enChIP analysis
In this study, we generated transgenic mice expressing 3xFLAG‐tagged Streptococcus pyogenes dCas9 (3xFLAG‐dCas9) and retrovirally transduced gRNA into primary CD4+ T cells from these mice for enChIP. Using this approach, we achieved high yields of enChIP at the targeted genomic region. Our novel transgenic mouse lines provide a valuable tool for enChIP analysis in primary mouse cells.
In this study, we generated transgenic mice expressing 3xFLAG‐tagged Streptococcus pyogenes dCas9 (3xFLAG‐dCas9) and retrovirally transduced gRNA into primary CD4+ T cells from these mice for enChIP. Using this approach, we achieved ...
Source: Genes to Cells - February 26, 2018 Category: Genetics & Stem Cells Authors: Toshitsugu Fujita, Fusako Kitaura, Asami Oji, Naoki Tanigawa, Miyuki Yuno, Masahito Ikawa, Ichiro Taniuchi, Hodaka Fujii Tags: BRIEF REPORT Source Type: research
Transposable elements shape the human proteome landscape via formation of cis ‐acting upstream open reading frames
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - February 15, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - February 15, 2018 Category: Genetics & Stem Cells Source Type: research
Aggregatibacter actinomycetemcomitans infection causes DNA double ‐strand breaks in host cells
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - February 14, 2018 Category: Genetics & Stem Cells Source Type: research
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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - February 14, 2018 Category: Genetics & Stem Cells Source Type: research
Wingless signaling regulates winner/loser status in Minute cell competition
Genes to Cells,Volume 23, Issue 3, Page 234-240, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - February 12, 2018 Category: Genetics & Stem Cells Source Type: research
Requirement of the F ‐actin‐binding activity of l‐afadin for enhancing the formation of adherens and tight junctions
Genes to Cells,Volume 23, Issue 3, Page 185-199, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - February 12, 2018 Category: Genetics & Stem Cells Source Type: research
