The role of ω‐subunit of Escherichia coli RNA polymerase in stress response
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - March 15, 2018 Category: Genetics & Stem Cells Source Type: research

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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - March 15, 2018 Category: Genetics & Stem Cells Source Type: research

The role of ω‐subunit of Escherichia coli RNA polymerase in stress response
In this study, we have performed UV cross‐linking experiments using 32P azido‐labeled ppGpp to probe its association with RNAP in the absence and presence of ω, and observed weaker binding of ppGpp to the RNAP without ω. Furthermore, we followed the binding kinetics of ppGpp to RNAP with and without ω by isothermal titration calorimetry and found it to be concurrent with the cross‐linking results. Native ω is intrinsically disordered, and we have used a previously characterized structured mutant of ω, which affects the plasticity of the active site of RNAP. Results show that the flexibility conferred by the unst...
Source: Genes to Cells - March 15, 2018 Category: Genetics & Stem Cells Authors: Neerupma Bhardwaj, Kirtimaan Syal, Dipankar Chatterji Tags: ORIGINAL ARTICLE Source Type: research

Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo
This study demonstrates that appropriate control of Nrf2 activity by Keap1 is essential for maintaining bone homeostasis. (Source: Genes to Cells)
Source: Genes to Cells - March 15, 2018 Category: Genetics & Stem Cells Authors: Eiki Yoshida, Takafumi Suzuki, Masanobu Morita, Keiko Taguchi, Kohei Tsuchida, Hozumi Motohashi, Minoru Doita, Masayuki Yamamoto Tags: BRIEF REPORT Source Type: research

Issue Information
Genes to Cells,Volume 23, Issue 3, Page 117-121, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Source Type: research

Announcement
Genes to Cells,Volume 23, Issue 3, Page 248-248, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Source Type: research

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Genes to Cells,Volume 23, Issue 3, Page 117-121, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Source Type: research

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Genes to Cells,Volume 23, Issue 3, Page 248-248, March 2018. (Source: Genes to Cells)
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Source Type: research

Announcement
(Source: Genes to Cells)
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Authors: Mitsuhiro Yanagida Tags: ANNOUNCEMENT Source Type: research

Issue Information
Front cover: Researchers measured the concentration of various metabolites in plasma or red blood cells taken from volunteers, and found metabolites whose concentration was specifi cally higher or lower in elderly individuals. In this picture, two researchers are spreading these compound structure formulae beside them, and discussing correlations of concentration between two metabolites by plotting scatter charts using a lattice of a shoji door. A bamboo fence that is likened to a clustered heatmap of metabolites can be seen over there. For drawing this image, we referred to a research paper by Chaleckis et al. (2016) Proc...
Source: Genes to Cells - March 13, 2018 Category: Genetics & Stem Cells Tags: ISSUE INFORMATION Source Type: research

Atomic force microscopy analysis of SasA ‐KaiC complex formation involved in information transfer from the KaiABC clock machinery to the output pathway in cyanobacteria
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - March 12, 2018 Category: Genetics & Stem Cells Source Type: research

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Genes to Cells, Ahead of Print. (Source: Genes to Cells)
Source: Genes to Cells - March 12, 2018 Category: Genetics & Stem Cells Source Type: research

Dullard deficiency causes hemorrhage in the adult ovarian follicles
Genes to Cells, EarlyView. (Source: Genes to Cells)
Source: Genes to Cells - March 9, 2018 Category: Genetics & Stem Cells Source Type: research