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Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 231-239, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 30, 2018 Category: Cancer & Oncology Source Type: research
Promoter hypermethylation inactivate tumor suppressor FAM134B and is associated with poor prognosis in colorectal cancer
Abstract
The present study aims to examine promoter methylation status of FAM134B in a large cohort of patients with colorectal adenocarcinomas. The clinical significances and correlations of FAM134B promoter methylation with its expression are also analysed. Methylation‐specific high‐resolution melt‐curve analysis followed by sequencing was used to identify FAM134B promoter methylation in colorectal adenomas (N = 32), colorectal adenocarcinomas (N = 164), matched adjacent non‐neoplastic colorectal mucosae (N = 83) and colon cancer cell lines (N = 4). FAM134B expression was studied by real‐time quantitati...
Source: Genes, Chromosomes and Cancer - January 30, 2018 Category: Cancer & Oncology Authors: Farhadul Islam, Vinod Gopalan, Suja Pillai, Cu ‐tai Lu, Kais Kasem, Alfred King‐yin Lam Tags: RESEARCH ARTICLE Source Type: research
Cancer etiology: Variation in cancer risk among tissues is poorly explained by the number of gene mutations
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 29, 2018 Category: Cancer & Oncology Authors: Miguel L ópez‐Lázaro Tags: Perspective Article Source Type: research
RREB1 –MKL2 fusion in biphenotypic “oropharyngeal” sarcoma: New entity or part of the spectrum of biphenotypic sinonasal sarcomas?
Abstract
An increasing number of sarcomas displaying a primitive, monomorphic spindle cell phenotype have been shown to harbor recurrent gene fusions, including biphenotypic sinonasal sarcoma (SNS). Occurring in the sinonasal area of middle‐aged patients, SNS is a locally aggressive tumor harboring in 90% of cases recurrent gene fusions involving the PAX3 gene, in which the chimeric transcription factor induces an aberrant dual myogenic and neural phenotype. Here, we report an unusual oropharyngeal monomorphic spindle cell sarcoma in a 53‐year‐old man that revealed a novel RREB1–MKL2 gene fusion by RNA sequencing w...
Source: Genes, Chromosomes and Cancer - January 25, 2018 Category: Cancer & Oncology Authors: Aurore Siegfried, Claire Romary, Fr éderic Escudié, Yvan Nicaise, David Grand, Philippe Rochaix, Béatrice Barres, Sébastien Vergez, Christine Chevreau, Jean‐Michel Coindre, Emmanuelle Uro‐Coste, Sophie Le Guellec Tags: RESEARCH ARTICLE Source Type: research
NKX6.1 hypermethylation predicts the outcome of stage II colorectal cancer patients undergoing chemotherapy
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 24, 2018 Category: Cancer & Oncology Authors: Sou ‐Yi Chang, Chih‐Chi Kuo, Chang‐Chieh Wu, Cheng‐Wen Hsiao, Je‐Ming Hu, Chih‐Hsiung Hsu, Yu‐Ching Chou, Yu‐Lueng Shih, Ya‐Wen Lin Tags: Research Article Source Type: research
NKX6.1 hypermethylation predicts the outcome of stage II colorectal cancer patients undergoing chemotherapy
Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 268-277, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 24, 2018 Category: Cancer & Oncology Source Type: research
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Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 268-277, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 24, 2018 Category: Cancer & Oncology Source Type: research
Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 23, 2018 Category: Cancer & Oncology Authors: Meriem Benfodda, Steven Gazal, Vincent Descamps, Nicole Basset ‐Seguin, Lydia Deschamps, Luc Thomas, Philippe Saiag, Roberto Zanetti, Lidia Sacchetto, Giovanna Chiorino, Maria Scatolini, Bernard Grandchamp, Nadem Soufir Tags: Research Article Source Type: research
DSP30 and interleukin ‐2 as a mitotic stimulant in B‐cell disorders including those with a low disease burden
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 19, 2018 Category: Cancer & Oncology Authors: Karen A Dun, Louise A Riley, Giuseppe Diano, Leanne B Adams, Eleanor Chiu, Archna Sharma Tags: Research Article Source Type: research
DSP30 and interleukin ‐2 as a mitotic stimulant in B‐cell disorders including those with a low disease burden
Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 260-267, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: research
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Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 260-267, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 19, 2018 Category: Cancer & Oncology Source Type: research
Incidence and prognostic impact of cytogenetic aberrations in patients with systemic mastocytosis
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 17, 2018 Category: Cancer & Oncology Authors: Nicole Naumann, Mohamad Jawhar, Juliana Schwaab, Sebastian Kluger, Johannes L übke, Georgia Metzgeroth, Henning D. Popp, Nada Khaled, Hans‐Peter Horny, Karl Sotlar, Peter Valent, Claudia Haferlach, Gudrun Göhring, Brigitte Schlegelberger, Manja Meggen Tags: Research Article Source Type: research
Incidence and prognostic impact of cytogenetic aberrations in patients with systemic mastocytosis
Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 252-259, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 17, 2018 Category: Cancer & Oncology Source Type: research
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Genes, Chromosomes and Cancer,Volume 57, Issue 5, Page 252-259, May 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 17, 2018 Category: Cancer & Oncology Source Type: research
Table of Content Volume 57, Number 3, March 2018
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 12, 2018 Category: Cancer & Oncology Tags: ISSUE INFORMATION ‐ TOC Source Type: research
