Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - March 10, 2017 Category: Cancer & Oncology Authors: Zheng Chen, Mohammed Soutto, Bushra Rahman, Muhammad W Fazili, DunFa Peng, Maria Blanca Piazuelo, Heidi Chen, M. Kay Washington, Yu Shyr, Wael El ‐Rifai Tags: Research Article Source Type: research

ETV Transcriptional Upregulation is More Reliable Than RNA Sequencing Algorithms and FISH in Diagnosing Round Cell Sarcomas with CIC Gene Rearrangements
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 24, 2017 Category: Cancer & Oncology Authors: Yu ‐Chien Kao, Yun‐Shao Sung, Chun‐Liang Chen, Lei Zhang, Brendan C Dickson, David Swanson, Sumathi Vaiyapuri, Farida Latif, Abdullah Alholle, Shih‐Chiang Huang, Jason L Hornick, Cristina R Antonescu Tags: Research Article Source Type: research

Promotion of Invasion by Mutant RAS is Dependent on Activation of the WASF3 Metastasis Promoter Gene
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 23, 2017 Category: Cancer & Oncology Authors: Yong Teng, Lambert Ngoka, John K Cowell Tags: Research Article Source Type: research

Table of Content Volume 56, Number 4, April 2017
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 15, 2017 Category: Cancer & Oncology Tags: Issue Information ‐ TOC Source Type: research

Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 15, 2017 Category: Cancer & Oncology Authors: Liat Goldberg, Sheryl M Gough, Fan Lee, Christine Dang, Robert L. Walker, Yeulin J. Zhu, Sven Bilke, Marbin Pineda, Masahiro Onozawa, Yang Jo Chung, Paul S. Meltzer, Peter D. Aplan Tags: Research Article Source Type: research

Comprehensive Genomic and Phenotypic Characterization of Germline FH Deletion in Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC)
This study evaluated the prevalence and clinical phenotype of FH deletions in HLRCC patients. Patients with phenotypic manifestations consistent with HLRCC who lacked detectable germline FH intragenic mutations were investigated for FH deletion. A series of 28 patients from 13 families were evaluated using a combination of a comparative genomic hybridization (CGH) array and/or CLIA‐approved FH deletion/duplication analyses. Thirteen distinct germline deletions were identified in the 13 UOB families, including 11 complete FH gene deletions and two partial FH gene deletions. The size of eight evaluated complete FH deletion...
Source: Genes, Chromosomes and Cancer - February 13, 2017 Category: Cancer & Oncology Authors: Cathy D. Vocke, Christopher J. Ricketts, Maria J. Merino, Ramaprasad Srinivasan, Adam R. Metwalli, Lindsay A. Middelton, James Peterson, Youfeng Yang, W. Marston Linehan Tags: Research Article Source Type: research

TMEM16A/ANO1 Suppression Improves Response to Antibody Mediated Targeted Therapy of EGFR and HER2/ERBB2
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 9, 2017 Category: Cancer & Oncology Authors: Sucheta Kulkarni, Anke Bill, Neal R. Godse, Nayel I. Khan, Jason I. Kass, Kevin Steehler, Carolyn Kemp, Kara Davis, Carol A. Bertrand, Avani R. Vyas, Douglas E. Holt, Jennifer R. Grandis, L Alex Gaither, Umamaheswar Duvvuri Tags: Research Article Source Type: research

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 6, 2017 Category: Cancer & Oncology Authors: I. Gladek, J. Ferdin, S. Horvat, G.A. Calin, T. Kunej Tags: Review Article Source Type: research

Candidate susceptibility variants for esophageal squamous cell carcinoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - February 5, 2017 Category: Cancer & Oncology Authors: Iikki Donner, Riku Katainen, Tomas Tanskanen, Eevi Kaasinen, Mervi Aavikko, Kristian Ovaska, Miia Artama, Eero Pukkala, Lauri A. Aaltonen Tags: Research Article Source Type: research

Confirmation of mutation landscape of NF1 ‐associated malignant peripheral nerve sheath tumors
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 26, 2017 Category: Cancer & Oncology Authors: Pierre Sohier, Armelle Luscan, Angharad Lloyd, Kevin Ashelford, Ingrid Laurendeau, Audrey Briand ‐Suleau, Dominique Vidaud, Nicolas Ortonne, Eric Pasmant, Meena Upadhyaya Tags: Research Article Source Type: research

BRCA1 Alterations with Additional Defects in DNA Damage Response Genes May Confer Chemoresistance to BRCA ‐like Breast Cancers Treated with Neoadjuvant Chemotherapy
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 24, 2017 Category: Cancer & Oncology Authors: Mamoru Takada, Shigenori Nagai, Masayuki Haruta, Ryuichi P. Sugino, Katsunori Tozuka, Hiroyuki Takei, Fumie Ohkubo, Kenichi Inoue, Masafumi Kurosumi, Masaru Miyazaki, Aiko Sato ‐Otsubo, Yusuke Sato, Seishi Ogawa, Yasuhiko Kaneko Tags: Research Article Source Type: research

Table of Content Volume 56, Number 3, March 2017
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 13, 2017 Category: Cancer & Oncology Tags: Issue Information ‐ TOC Source Type: research

Comparable Clinical Outcomes in Patients with HER2 ‐mutant and EGFR‐mutant Lung Adenocarcinomas
In conclusion, lung ADC harboring HER2 mutations showed distinct characteristics from other driver mutations, including increased chemosensitivity with in advanced stage disease. This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 7, 2017 Category: Cancer & Oncology Authors: Chien ‐Hung Gow, Hou‐Tai Chang, Chor‐Kuan Lim, Chao‐Yu Liu, Jin‐Shing Chen, Jin‐Yuan Shih Tags: Research Article Source Type: research

Cross ‐Species Analysis of the Canine and Human Bladder Cancer Transcriptome and Exome
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - January 4, 2017 Category: Cancer & Oncology Authors: Stephen A. Ramsey, Tanjin Xu, Cheri Goodall, Adelaide C. Rhodes, Amita Kashyap, Jun He, Shay Bracha Tags: Research Article Source Type: research

BCOR upregulation in a poorly differentiated synovial sarcoma with SS18L1 ‐SSX1 fusion—A pathologic and molecular pitfall
The diagnosis of poorly differentiated synovial sarcoma (PD‐SS) may be challenging due to overlapping morphologic features with other undifferentiated round cell sarcomas (URCS). Particularly relevant is the histologic overlap and shared BCOR overexpression between a subset of SS and URCS with various BCOR genetic abnormalities. Here, we report a case of PD‐SS lacking the canonical SS18‐SSX gene fusion, but showing strong BCOR immunoreactivity and BCOR gene abnormalities by FISH, which were misinterpreted as a URCS with BCOR gene rearrangements. The tumor had an unusual clinical presentation arising as an intraneural...
Source: Genes, Chromosomes and Cancer - January 3, 2017 Category: Cancer & Oncology Authors: Yu ‐Chien Kao, Yun‐Shao Sung, Lei Zhang, Samuel Kenan, Samuel Singer, William D. Tap, David Swanson, Brendan C. Dickson, Cristina R. Antonescu Tags: Research Article Source Type: research