Functions of the multi ‐interacting protein KIDINS220/ARMS in cancer and other pathologies
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 27, 2017 Category: Cancer & Oncology Authors: Muhammad ‐Zawwad Raza, Simone Allegrini, Charles Dumontet, Lars Petter Jordheim Tags: Review Article Source Type: research
Table of Content Volume 57, Number 1, January 2018
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 15, 2017 Category: Cancer & Oncology Tags: ISSUE INFORMATION ‐ TOC Source Type: research
Comprehensive study of three novel cases of TFEB ‐amplified renal cell carcinoma and review of the literature: evidence for a specific entity with poor outcome
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 11, 2017 Category: Cancer & Oncology Authors: Lionel Mendel, Damien Ambrosetti, Yohan Bodokh, M élanie Ngo‐Mai, Matthieu Durand, Cécile Simbsler‐Michel, Mickael Delhorbe, Jean Amiel, Florence Pedeutour Tags: Perspective Article Source Type: research
Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery
In conclusion, we show that several CRC risk SNPs detect subpopulations of rectal cancer patients with poor prognosis, and that rs6983267 probably affects prognosis through interfering with the resistance of cancer cells to CRT. This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 9, 2017 Category: Cancer & Oncology Authors: Yue Hu, Jochen Gaedcke, Georg Emons, Tim Beissbarth, Marian Grade, Peter Jo, Meredith Yeager, Stephen J. Chanock, Hendrik Wolff, Jordi Camps, B. Michael Ghadimi, Thomas Ried Tags: Research Article Source Type: research
High Sensitivity of FISH Analysis in Detecting Homozygous SMARCB1 Deletions in Poorly Differentiated Chordoma: A Clinicopathologic and Molecular Study of 9 Cases
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 9, 2017 Category: Cancer & Oncology Authors: Adepitan A. Owosho, Lei Zhang, Marc K Rosenblum, Cristina R. Antonescu Tags: Research Article Source Type: research
Trichostatin A preferentially reverses the upregulation of gene ‐expression levels induced by gain of chromosome 7 in colorectal cancer cell lines
Epithelial cancers are defined by a tumor‐specific distribution of chromosomal aneuploidies that are maintained when cells metastasize and are conserved in cell lines derived from primary tumors. Correlations between genomic copy number and gene expression have been observed for different tumors including, colorectal (CRC), breast, and pancreatic cancer. These ploidy‐driven transcriptional deregulations are characterized by low‐level expression changes of most genes on the affected chromosomes. The emergence of these aberrations at an early stage of tumorigenesis and the strong selection for the maintenance of these ...
Source: Genes, Chromosomes and Cancer - October 30, 2017 Category: Cancer & Oncology Authors: Floryne O. Buishand, Eric Cardin, Yue Hu, Thomas Ried Tags: RESEARCH ARTICLE Source Type: research
Clinical features and biological implications of different U2AF1 mutation types in myelodysplastic syndromes
In conclusion, our study indicates that U2AF1MT is one of the earliest genetic events in MDS patients and that different types of U2AF1MT have distinct clinical and biological characteristics. This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 23, 2017 Category: Cancer & Oncology Authors: Bing Li, Jinqin Liu, Yujiao Jia, Jingya Wang, Zefeng Xu, Tiejun Qin, Zhongxun Shi, Zhen Song, Shuailing Peng, Huijun Huang, Liwei Fang, Hongli Zhang, Lijuan Pan, Naibo Hu, Shiqiang Qu, Yue Zhang, Jian Wu, Na Liu, Kun Ru, Gang Huang, Zhijian Xiao Tags: Research Article Source Type: research
Bleomycin ‐induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 20, 2017 Category: Cancer & Oncology Authors: Michal Kroupa, Zdenka Polivkova, Sivaramakrishna Rachakonda, Michaela Schneiderova, Sona Vodenkova, Tomas Buchler, Katerina Jiraskova, Marketa Urbanova, Ludmila Vodickova, Kari Hemminki, Rajiv Kumar, Pavel Vodicka Tags: Research Article Source Type: research
Identification of somatic genetic alterations in ovarian clear cell carcinoma with next generation sequencing
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 17, 2017 Category: Cancer & Oncology Authors: Yusuke Shibuya, Hideki Tokunaga, Sakae Saito, Kazurou Shimokawa, Fumiki Katsuoka, Bin Li, Kaname Kojima, Masao Nagasaki, Masayuki Yamamoto, Nobuo Yaegashi, Jun Yasuda Tags: Research Article Source Type: research
Targeted Deep Sequencing of Effusion Cytology Samples is Feasible, informs Spatiotemporal Tumor Evolution, and has Clinical and Diagnostic Utility
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2017 Category: Cancer & Oncology Authors: Jonas Leichsenring, Anna ‐Lena Volckmar, Martina Kirchner, Daniel Kazdal, Mark Kriegsmann, Fabian Stögbauer, Teresa Bockmayr, Frederick Klauschen, Felix J.F. Herth, Roland Penzel, Arne Warth, Peter Schirmacher, Volker Endris, Albrecht Stenzinger Tags: Research Article Source Type: research
Table of Content Volume 56, Number 12, December 2017
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2017 Category: Cancer & Oncology Tags: ISSUE INFORMATION ‐ TOC Source Type: research
Loss of Heterozygosity and Uniparental Disomy of Chromosome Region 10q23.3 –26.3 in Glioblastoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 27, 2017 Category: Cancer & Oncology Authors: Ekaterina A Alekseeva, Ekaterina B Kuznetsova, Alexander S Tanas, Evgeny V Prozorenko, Anton M Zaytsev, Mikhail I Kurzhupov, Olga N Kirsanova, Viktoria V Rudenko, Vladimir V Strelnikov, Dmitry V Zaletaev Tags: Research Article Source Type: research
Transcription factors —Intricate players of the bone morphogenetic protein signaling pathway
Abstract
Bone morphogenetic proteins (BMPs) are a family of growth factors, some of which are known by the name growth and differentiation factor (GDF). BMPs were discovered in the 1960s in an attempt to find factors capable of inducing bone formation. By the end of 1980s, several different BMPs had been found and to date, around 20 members are known. Together with TGFβ, nodal, and activins, they comprise the TGFβ superfamily. BMPs are known to regulate cell fate both in development and adult tissues, and as such they are also involved in many disease states. Understanding the impact of BMPs in these processes requires i...
Source: Genes, Chromosomes and Cancer - September 27, 2017 Category: Cancer & Oncology Authors: M. Ampuja, Anne Kallioniemi Tags: REVIEW ARTICLE Source Type: research
Trichostatin A preferentially reverses the upregulation of gene expression levels induced by gain of chromosome 7 in colorectal cancer cell lines
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 23, 2017 Category: Cancer & Oncology Authors: Floryne O. Buishand, Eric Cardin, Yue Hu, Thomas Ried Tags: Research Article Source Type: research
Extreme Chromosome 17 Copy Number Instability is a Prognostic Factor in Patients with Gastroesophageal Adenocarcinoma: A Retrospective Cohort Study
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2017 Category: Cancer & Oncology Authors: Jacqueline E. Birkness, Neal G. Spada, Caitlyn Miller, James D. Luketich, Katie S. Nason, Weijing Sun, Jon M. Davison Tags: Research Article Source Type: research
