Copy Number Gain of 11q13.3 Genes Associates with Pathological Stage in Hypopharyngeal Squamous Cell Carcinoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2016 Category: Cancer & Oncology Authors: Samuel B. Pattle, Natasa Utjesanovic, Athena Togo, Lucy Wells, Brendan Conn, Hannah Monaghan, Elizabeth Junor, Ingolfur Johannessen, Kate Cuschieri, Simon Talbot Tags: Research Article Source Type: research

Novel Mouse Model Recapitulates Genome and Transcriptome Alterations in Human Colorectal Carcinomas
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2016 Category: Cancer & Oncology Authors: Nicole E. McNeil, Hesed M. Padilla ‐Nash, Floryne O. Buishand, Yue Hue, Thomas Ried Tags: Research Article Source Type: research

Genomic landscape of retinoblastoma in Rb ‐/‐p130‐/‐ mice resembles human retinoblastoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2016 Category: Cancer & Oncology Authors: Irsan E. Kooi, Saskia E. van Mil, David MacPherson, Berber M. Mol, Annette C. Moll, Hanne Meijers ‐Heijboer, Gertjan J.L. Kaspers, Jacqueline Cloos, Hein te Riele, Josephine C. Dorsman Tags: Research Article Source Type: research

Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma
In conclusion, p.Q787Q is neither a suitable prognostic nor predictive biomarker for ADC patients receiving anti‐EGFR therapy in first or second line of therapy. This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 16, 2016 Category: Cancer & Oncology Authors: Jonas Leichsenring, Anna ‐Lena Volckmar, Nikolaus Magios, Cristiano Manuel Morais de Oliveira, Roland Penzel, Regine Brandt, Martina Kirchner, Farastuk Bozorgmehr, Michael Thomas, Peter Schirmacher, Arne Warth, Volker Endris, Albrecht Stenzinger Tags: Research Article Source Type: research

Table of Content Volume 55, Number 12, December 2016
(Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 12, 2016 Category: Cancer & Oncology Tags: Issue Information ‐ TOC Source Type: research

Germline BAP1 Alterations in Familial Uveal Melanoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - October 11, 2016 Category: Cancer & Oncology Authors: Karan Rai, Robert Pilarski, Getachew Boru, Muneeb Rehman, Ahmad H. Saqr, James B. Massengill, Arun Singh, Meghan J. Marino, Frederick H. Davidorf, Colleen M. Cebulla, Mohamed Abdel ‐Rahman Tags: Research Article Source Type: research

T ‐Cell Acute Lymphoblastic Leukemia in Infants Has Distinct Genetic and Epigenetic Features Compared to Childhood Cases
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 27, 2016 Category: Cancer & Oncology Authors: Mareike Doerrenberg, Andreas Kloetgen, Kebria Hezaveh, Wilhelm W össmann, Kirsten Bleckmann, Martin Stanulla, Martin Schrappe, Alice C McHardy, Arndt Borkhardt, Jessica I Hoell Tags: Research Article Source Type: research

Epigenetic Silencing of miR ‐200c in Breast Cancer Is Associated with Aggressiveness and Is Modulated by ZEB1
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 23, 2016 Category: Cancer & Oncology Authors: Valentina Damiano, Giulia Brisotto, Silvia Borgna, Alessandra di Gennaro, Michela Armellin, Tiziana Perin, Michela Guardascione, Roberta Maestro, Manuela Santarosa Tags: Research Article Source Type: research

Parental origin of the deletion del(20q) in Shwachman ‐Diamond patients and loss of the paternally derived allele of the imprinted L3MBTL1 gene
Shwachman–Diamond syndrome (SDS) (OMIM 260400) is a rare autosomal recessive disease characterized by exocrine pancreatic insufficiency, skeletal, and hematological abnormalities and bone marrow (BM) dysfunction. Mutations in the SBDS gene cause SDS. Clonal chromosome anomalies are often present in BM, i(7)(q10) and del(20q) being the most frequent ones. We collected 6 SDS cases with del(20q): a cluster of imprinted genes, including L3MBTL1 and SGK2 is present in the deleted region. Only the paternal allele is expressed for these genes. Based on these data, we made the hypothesis that the loss of this region, in relation...
Source: Genes, Chromosomes and Cancer - September 20, 2016 Category: Cancer & Oncology Authors: Lucia Nacci, Roberto Valli, Rita Maria Pinto, Marco Zecca, Marco Cipolli, Jacopo Morini, Simone Cesaro, Emanuela Boveri, Vittorio Rosti, Paola Corti, Maura Ambroni, Francesco Pasquali, Cesare Danesino, Emanuela Maserati, Antonella Minelli Tags: Research Article Source Type: research

Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 17, 2016 Category: Cancer & Oncology Authors: Noralane M. Lindor, Melissa C. Larson, Melissa S. DeRycke, Shannon K. McDonnell, Saurabh Baheti, Zachary C. Fogarty, Aung Ko Win, John D. Potter, Daniel D. Buchanan, Mark Clendenning, Polly A. Newcomb, Graham Casey, Steven Gallinger, Lo ïc Le Marchand, J Tags: Research Article Source Type: research

Familial Solitary Chondrosarcoma Resulting from Germline EXT2 Mutation
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2016 Category: Cancer & Oncology Authors: Abdelkader Heddar, Pierre Fermey, Sophie Coutant, Emilie Angot, Jean ‐Christophe Sabourin, Paul Michelin, Nathalie Parodi, Françoise Charbonnier, Myriam Vezain, Gaëlle Bougeard, Stéphanie Baert‐Desurmont, Thierry Frébourg, Isabelle Tournier Tags: Research Article Source Type: research

Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2016 Category: Cancer & Oncology Authors: Tobias Herold, Klaus H. Metzeler, Sebastian Vosberg, Luise Hartmann, Vindi Jurinovic, Sabrina Opatz, Nikola P. Konstandin, Stephanie Schneider, Evelyn Zellmeier, Bianka Ksienzyk, Alexander Graf, Stefan Krebs, Helmut Blum, Maria Cristina Sauerland, Thomas Tags: Research Article Source Type: research

Common Fragile Sites and Extremely Large are Targets for Human Papillomavirus Integrations and Chromosome Rearrangements in Oropharyngeal Squamous Cell Carcinoma
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2016 Category: Cancer & Oncology Authors: Ge Gao, Sarah H. Johnson, George Vasmatzis, Christina E. Pauley, Nicole M. Tombers, Jan L. Kasperbauer, David I. Smith Tags: Research Article Source Type: research

Multiple Biological Processes May be Associated with Tumorigenesis Under NUP88 ‐overexpressed Condition
In conclusion, our data for the first time provide a global view of biological processes that may drive tumorigenesis under NUP88 overexpressed condition, revealing a biological effect of NUP88‐MISP interaction. Furthermore, identification of NUP88‐associated proteins provides a valuable database for future studies. This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2016 Category: Cancer & Oncology Authors: Jiafeng Li, Jinsheng Zhao, Yue Li Tags: Research Article Source Type: research

Pediatric T ‐Cell Acute Lymphoblastic Leukemia
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - September 15, 2016 Category: Cancer & Oncology Authors: Kristina Karrman, Bertil Johansson Tags: Review Article Source Type: research