Biochemical composition of Predatory carp (Chanodichthys erythropterus) from Lake Dianshan, Shanghai, China
This study is focused on providing nutrient contents information of the wild east Asian native species Predatory carp (Chanodichthys erythropterus). The specimens were collected from Lake Dianshan, Shanghai-China. The body muscles of randomly selected fish species were dried at 105 °C in an oven and used for biochemical analysis. Protein, carbohydrate, ash, and moisture contents found in the experimental fish and their proportions were 48.7%, 14.1%, 5.1%, and 9.4%, respectively. Methionine is the major essential acid determined whiles Alanine was also the abundant for non-essential amino acids although ten of the most e...
Source: Egyptian Journal of Basic and Applied Sciences - October 22, 2017 Category: Science Source Type: research

Ariadne merione ecdysone receptor (AmEcR) protein: An in silico approach for comparison of agonist and antagonist compounds
Publication date: Available online 18 October 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Chandran Sundaravadivelan, Easwaran Murugesh, Mathew Preethy, Prabu Sivaprasath Ecdysteroid signal transduction plays a major role in insect metamorphosis, 20-hydroxyecdysone (20E) binds to the nuclear receptor composed of the ecdysone receptor ligand binding domine (EcR-LBD) and triggers the developmental transitions. Ariadne merione ecdysone receptor (AmEcR) cDNA was amplified and partially sequenced of about 553 bp, which encodes a polypeptide of 184 amino acids (aa). The theoretical molecular weig...
Source: Egyptian Journal of Basic and Applied Sciences - October 22, 2017 Category: Science Source Type: research

Preventive and curative effects of Cocculus hirsutus (Linn.) Diels leaves extract on CCl4 provoked hepatic injury in rats
In conclusion, extract from C. hirsutus could protect the liver from CCl4-induced oxidative damage, by scavenging the free radicals generated during the metabolism of CCl4. Graphical abstract (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - October 22, 2017 Category: Science Source Type: research

Design, synthesis, spectroscopic characterization and anti-psychotic investigation of some novel Azo dye/Schiff base/Chalcone derivatives
Publication date: Available online 22 October 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Chandravadivelu Gopi, Vedula Girija Sastry, Magharla Dasaratha Dhanaraju The purpose of the study is to design, synthesise and assess the antipsychotic activity of a set of the novel (5-(10-(3-N, N-Dimethylamino) propyl)-10H-phenothiazine-3-yl)-1,3,4-thiadiazo-2-yl) Azodye/Schiff base/Chalcone derivatives. The newly synthesised compound structure was characterised by FT-IR, 1H NMR, Mass spectroscopy and elemental analysis. Each compound has been shown an excellent anti-psychotic activity in a haloperidol...
Source: Egyptian Journal of Basic and Applied Sciences - October 22, 2017 Category: Science Source Type: research

Synthesis, antibacterial and molecular docking studies of new benzimidazole derivatives
Publication date: Available online 28 September 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Kumaraswamy Gullapelli, G. Brahmeshwari, M. Ravichander, Uma Kusuma The new analogs of benzimidazole fused heterocyclic compounds such as triazinane and oxadiazinanes were synthesised by classical amino methylation with different aryl-N,N′ unsymmetrical thioureas. The antibacterial activity of triazinane and oxadiazinane compounds have been assessed with zone of inhibition by well diffusion method using a panel of selected gram positive and gram negative bacterial strains and which have showed good ...
Source: Egyptian Journal of Basic and Applied Sciences - September 28, 2017 Category: Science Source Type: research

Synthesis and evaluation of N-(Substituted phenyl)-2-(3-substituted) sulfamoyl) phenyl) acetamide derivatives as anticancer agents
Publication date: Available online 23 September 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Chandrakant D. Pawar, Aniket P. Sarkate, Kshipra S. Karnik, Devanand B. Shinde A series of molecules containing sulfonyl and amide coupling structure were developed, synthesized and evaluated. Total 21 compounds having sulfonamide and amide groups are synthesized. The structures of the synthesized compounds were elucidated and confirmed by 1H NMR, 13C NMR, Mass spectrum and the purity was checked through HPLC analysis. All synthesized compounds (4a–4u) were tested for their in vitro anticancer activ...
Source: Egyptian Journal of Basic and Applied Sciences - September 24, 2017 Category: Science Source Type: research

Central neurocytoma of the third ventricle: Case report and treatment review
Publication date: Available online 8 August 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Mehjabeen Marri, Iftikhar Ahmad, Khushnaseeb Ahmad, Zoonish Ashfaq Central neurocytoma is a rare tumor of neuronal differentiation which is typically seen in young adults. Here, we report a case of a 25years old female patient who presented with central neurocytoma of the third ventricle. Sub-total resection of the tumor was carried out via left parieto-occipital craniotomy. Afterwards, the patient received conventional radiotherapy (i.e., 54Gy/27 fractions). We observed marked improvement in terms of tum...
Source: Egyptian Journal of Basic and Applied Sciences - August 9, 2017 Category: Science Source Type: research

Azoreductase kinetics and gene expression in the synthetic dyes-degrading Pseudomonas
In this study, two 16S rRNA identified Pseudomonas aeruginosa bacterial isolates (ASU3 and ASU6) have been screened to enzymatically degrade both Disperse Blue 64 (DB64) and Acid Yellow 17 (AY17) which resembles 2 of the synthetic dyes that causes aquatic environmental pollution. The expression of the azoR1 gene has been detected in the strains, the degradation percentage of DB64 and AY17 by stain ASU6 was found to exceed the ASU3. This returned to the differences in the expression levels of azoR1 between the ASU6 and the ASU3 which was confirmed by RT-PCR. In addition, the specific activity (U/mg protein) of azoreductase ...
Source: Egyptian Journal of Basic and Applied Sciences - August 1, 2017 Category: Science Source Type: research

Anti-cancer potential of a mix of natural extracts of turmeric, ginger and garlic: A cell-based study
This study was designed to investigate the aqueous natural extracts mixture (NE mix) prepared from common spices turmeric, ginger and garlic for its free radical scavenging potential and anti-cancer property against human breast cancer cell lines (MCF-7, ZR-75 and MDA-MB 231). Qualitative analysis of their bioactive constituents from turmeric, ginger and garlic were done using liquid chromatography-ESI- mass spectrometry (LC-ESI-MS/MS). To the best of our knowledge, NE mix with and without Tamoxifen has not been tested for its anti-cancer potential. We observed that the NE mix induced apoptosis in all the breast cancer cel...
Source: Egyptian Journal of Basic and Applied Sciences - July 29, 2017 Category: Science Source Type: research

Effect of celecoxib and cisplatin combination on apoptosis and cell proliferation in a mouse model of chemically-induced colonic aberrant crypt foci
This study investigates a possible synergistic function for celecoxib in cisplatin-based chemotherapy against chemically-induced colon carcinogenesis in mice. Mice received fifteen injections of 1,2-dimethylhydrazine dihydrochloride (DMH; 20mg/kg/week), s.c. to induce colon carcinogenesis and the normal control group received equal volumes of normal saline. Mice were randomly divided into five groups, (I) normal control group, (II) DMH control group (III) DMH+cisplatin (4mg/kg/week, i.p.) group, (IV) DMH+celecoxib (10mg/kg/day by gavage) group and (V) DMH+cisplatin+celecoxib group. Drugs were administered starting from wee...
Source: Egyptian Journal of Basic and Applied Sciences - July 28, 2017 Category: Science Source Type: research

The success story of the implementation of the national food safety agency in Ivory Coast
Publication date: Available online 22 July 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Montet Didier, Akaki David, Moretti Christine, Brabet Catherine, Manizan Ama Lethicia, Elleingand Eric, Baud Guillaume, Mens Frédéric, Yao Benjamin, Michel Thomas, Assidjo Emmanuel, Aw Sadat, Akmel Clément, Hubert Assin, Durand Noel, Alter Pascaline, Berthiot Laurent, Métayer Isabelle, Tape Thierry The 3C Ivoire EuropeAid project (2011–2015), set up a coordination committee in Ivory Coast to evaluate the effectiveness of sanitary controls, prevent sanitary risks and coordinate nationwi...
Source: Egyptian Journal of Basic and Applied Sciences - July 23, 2017 Category: Science Source Type: research

Antioxidant and anti-inflammatory effects of dimethyl fumarate in hypercholesterolemic rabbits
In conclusion, this study suggests that DMF has the ability to improve HCD-induced vascular irregularities, possibly via its anti-inflammatory and antioxidant effect. (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - July 16, 2017 Category: Science Source Type: research

New, simple, sensitive and validated spectrophotometric method for the determination of salicylhydroxamic acid in capsules and raw material according to the ICH guidelines
Publication date: Available online 14 July 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Khaldun Mohammad Al Azzam, Wafaa El Kassed This work was aimed to develop a rapid, simple, selective, and precise spectrophotometric method for the estimation of salicylhydroxamic acid found in both capsules and raw materials. Spectrophotometric detection was conducted at maximum absorption of 294nm with the aids of methanol: water (1:99, v/v) as solvent. The figures of merit of the newly developed method were validated for linearity, specificity, accuracy, precision, robustness, ruggedness, limit of detecti...
Source: Egyptian Journal of Basic and Applied Sciences - July 15, 2017 Category: Science Source Type: research

The role of thymoquinone as a potent antioxidant in ameliorating the neurotoxic effect of sodium arsenate in female rat
In conclusion, TQ ameliorated the neurotoxic effect of arsenate and suppressed the oxidative stress induced in the nervous system through its antioxidant mechanism. (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - July 15, 2017 Category: Science Source Type: research

Uptake of Cu2+ and Zn2+ from simulated wastewater using muskmelon peel biochar: Isotherm and kinetic studies
Publication date: Available online 28 June 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Tabrez Alam Khan, Amer Arif Mukhlif, Equbal Ahmad Khan The muskmelon peel, an abundant common food waste material, has been gainfully utilized for the production of biochar. The biosorptive characteristics of muskmelon peel biochar towards copper(II) and zinc(II) from water are investigated. The biochar is characterized by infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) studies. The various process parameters for the removal of copper(II) and zinc(II) usin...
Source: Egyptian Journal of Basic and Applied Sciences - June 29, 2017 Category: Science Source Type: research