Egyptian Journal of Basic and Applied Sciences This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Analysis of efficiency of different antennas for microwave ablation using simulation and experimental methods
The objective of this study is to analyze the efficiency of different antennas proposed for microwave ablation therapy using numerical simulation and experimental approach. The simulation was done with COMSOL MULTIPHYSICS® software to design antenna prototypes and evaluate its reflection coefficient, power dissipation distribution, power dissipation density, specific absorption rate and temperature distribution in tissue. Antennas were fabricated from a 50 Ω RG405/U semi-rigid coaxial cable to match the geometric prototypes generated during simulation. Ex vivo bovine livers were ablated with the fabricated antennas usi...
Source: Egyptian Journal of Basic and Applied Sciences - February 6, 2018 Category: Science Source Type: research

A comparative study on larvicidal potential of selected medicinal plants over green synthesized silver nano particles
Publication date: Available online 1 February 2018 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Syed Zameer Ahmed Khader, Sidhra Syed Zameer Ahmed, Jagadeeswari Sathyan, Mohamed Rafi Mahboob, Kisore P. Venkatesh, Kishore Ramesh Larvicidal activity was assessed for alcoholic extracts of Phyllanthus amarus, Annona squamosa, Coccinia grandis and Eclipta prostrata extracted using solvents of various polarity. Third instar stage larvae of Dengue-vector, Aedes aegypti and Japanese encephalitis (JE) causing mosquito Culex tritaeniorhynchus were subjected to larvicidal bioassay at various concentrations...
Source: Egyptian Journal of Basic and Applied Sciences - February 2, 2018 Category: Science Source Type: research

Thioredoxin-1 and MMP-9 as biomarkers in breast cancer metastasis in Egyptian female patients
Publication date: Available online 12 January 2018 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Al Shaima G. Abd El Salam, Mohamed A. Ebrahim, Laila A. Eissa, Mamdouh M. El-Shishtawy (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - January 24, 2018 Category: Science Source Type: research

Molecular docking and QSAR analysis of a few Gama amino butyric acid aminotransferase inhibitors
Publication date: Available online 18 January 2018 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Usman Abdulfatai, Adamu Uzairu, Sani Uba Molecular docking and quantitative structure–activity relationship (QSAR) studies were carried out on 37 anticonvulsant compounds to develop a robust model for the prediction of anticonvulsant activities against Gama amino butyric acid aminotransferase (GABAAT) and to determine the dominant structural amino acid residues responsible for the binding affinity of the ligand-GABAAT complex. AutoDock Vina of PyRx virtual screening software was used to perform the mol...
Source: Egyptian Journal of Basic and Applied Sciences - January 24, 2018 Category: Science Source Type: research

Visfatin gene expression and oxidative stress in pregnancy induced hypertension
This study was conducted with the aim of evaluating the level of visfatin gene expression in placenta and measuring some oxidative stress parameters. Eighty Egyptian patients of newly diagnosed pregnant hypertensive disorder were selected for the study which was recruited from Mansoura University Hospital, Department of Obstetrics and Gynecology and also normotensive pregnant women were collected. The pregnant women groups were classified into four groups: gestational hypertension (n = 20), mild preeclampsia (n = 16), severe preeclampsia (n = 25), chronic hypertension with superimposed preeclampsia (n = 19)...
Source: Egyptian Journal of Basic and Applied Sciences - December 27, 2017 Category: Science Source Type: research

Cancer preventive and therapeutic effects of EGCG, the major polyphenol in green tea
Publication date: Available online 19 December 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Islam Rady, Hadir Mohamed, Mohamad Rady, Imtiaz A. Siddiqui, Hasan Mukhtar (-)-epigallocatechin-3-gallate (EGCG), the major bioactive catechin in green tea (GT) has been studied for almost past thirty years as an agent initially for its cancer chemoprevention effects and then for its cancer chemotherapeutic ability. This agent has shown considerable anti-cancer effects in a variety of preclinical cell culture and animal model systems. However, its clinical application to human patients is hampered by ...
Source: Egyptian Journal of Basic and Applied Sciences - December 19, 2017 Category: Science Source Type: research

The vasorelaxant effect of Canarium odontophyllum Miq. (Dabai) extract in rat thoracic aorta
Conclusion This study suggests that the vasorelaxant effect of aqueous extract from CO leaves was endothelium-independent and was possibly mediated through the blockade of voltage-dependent calcium channel and receptor-operated calcium channel. (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - December 6, 2017 Category: Science Source Type: research

Phytochemical screening, antioxidant, anti-inflammatory and antiangiogenic activities of Lophira procera A. Chev. (Ochnaceae) medicinal plant from Gabon
The objective of this study was to perform phytochemical screening, to determine the content of phenolic compound, to evaluate antioxidant, anti-inflammatory and antiangiogenic activities of ethanol, water-ethanol and water extracts of Lophira procera. Antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and phosphomolybdenum assay, anti-inflammatory activity by proteins denaturation inhibition and membranes stabilization test and antiangiogenic activity by chicken chorioallantoic membrane (CAM) method. The results showed that this plant is rich in saponins, polyphenols, tannins, total flavonoids, pr...
Source: Egyptian Journal of Basic and Applied Sciences - December 6, 2017 Category: Science Source Type: research

Synthesis, characterization and anticancer activity of vincristine loaded folic acid-chitosan conjugated nanoparticles on NCI-H460 non-small cell lung cancer cell line
Publication date: Available online 26 November 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Naresh Kumar, Raj Kumar Salar, Minakshi Prasad, Koushlesh Ranjan Vincristine has been used to treat different type of cancers. But unwanted side effects limit their applications in medicine. To overcome these side effects by targeted drug delivery approach, we synthesized vincristine loaded folic acid-chitosan conjugated nanoparticles by ionic gelation method. The nanoparticles were characterized using Dynamic Light Scattering (DLS), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Mic...
Source: Egyptian Journal of Basic and Applied Sciences - November 27, 2017 Category: Science Source Type: research

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of benzimidazole derivatives
Publication date: Available online 14 November 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Snehlata Yadav, Balasubramanian Narasimhan, Siong M. Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed A.A. Shah, Abhishek Mathur A series of benzimidazole derivatives (1–20) was synthesized and evaluated for its in vitro antimicrobial, antitubercular and anticancer activities. Compound 10 was found to be the most active antibacterial agent. The compounds active in in vitro evaluation against M. tuberculosis were further assessed for their in vivo activity in mice and for their capacity to inhibit the...
Source: Egyptian Journal of Basic and Applied Sciences - November 15, 2017 Category: Science Source Type: research

Polyphenon-E encapsulated into chitosan nanoparticles inhibited proliferation and growth of Ehrlich solid tumor in mice
In conclusion, encapsulation of PE into CSNPs provided a good platform for cancer chemotherapy and raised existing application of different polyphenols for nanochemotherapy/prevention. Graphical abstract (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - November 14, 2017 Category: Science Source Type: research

Attenuation of Bleomycin-induced pulmonary fibrosis in rats by flavocoxid treatment
In conclusion; flavocoxid can be proposed to be a potential therapeutic agent for management of pulmonary fibrosis. (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - November 3, 2017 Category: Science Source Type: research

Efficacy of silver nanoparticles mediated by Jania rubens and Sargassum dentifolium macroalgae; Characterization and biomedical applications
Publication date: Available online 31 October 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Hani Saber, Eman A. Alwaleed, K.A. Ebnalwaled, Asmaa Sayed, Wesam Salem Jania rubens and Sargassum dentifolium aqueous extracts were used as a reducing agent for the synthesis of silver nanoparticles (Ag-NPs). The prepared Ag-NPs have two plasmon absorption bands at 440 nm and 420 nm, with a direct band gap 2.25 eV and 2.38 eV for Ag-NPs/J. rubens and Ag-NPs/S. dentifolium respectively. From the FTIR results, the reduction has mostly been carried out by CN, hydroxyl or sulfated polysaccharides ...
Source: Egyptian Journal of Basic and Applied Sciences - November 1, 2017 Category: Science Source Type: research

Primary testicular diffuse large B-cell lymphoma: A case report
Publication date: Available online 31 October 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Muhammad Sadiq, Iftikhar Ahmad, Jamila Shuja, Zia Ullah Khan, Khushnaseeb Ahmad Primary testicular diffuse large-B cell lymphoma (DLBCL) is an uncommon and aggressive disease with predominant manifestation in the older age. Herein, we report a case of 47-year-old male patient who presented with three months history of left testis swelling. The patient underwent unilateral (left) radical orchiectomy. Histopathological examination revealed extensive involvement and replacement of testicular parenchyma by...
Source: Egyptian Journal of Basic and Applied Sciences - November 1, 2017 Category: Science Source Type: research

Synthesis and evaluation of [N-(Substituted phenyl)-2-(3-substituted) sulfamoyl) phenyl)] acetamide derivatives as anticancer agents
Publication date: Available online 23 September 2017 Source:Egyptian Journal of Basic and Applied Sciences Author(s): Chandrakant D. Pawar, Aniket P. Sarkate, Kshipra S. Karnik, Devanand B. Shinde A series of molecules containing sulfonyl and amide coupling structure were developed, synthesized and evaluated. Total 21 compounds having sulfonamide and amide groups are synthesized. The structures of the synthesized compounds were elucidated and confirmed by 1H NMR, 13C NMR, Mass spectrum and the purity was checked through HPLC analysis. All synthesized compounds (4a–4u) were tested for their in vitro anticancer activ...
Source: Egyptian Journal of Basic and Applied Sciences - October 22, 2017 Category: Science Source Type: research