Computer Methods and Programs in Biomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The effect of medication therapy management service combined with a national PharmaCloud system for polypharmacy patients
Polypharmacy over-burdens medical finances, increases inappropriate prescriptions, reduces patient medication adherence, and increases drug interactions [1 –5]. It is especially common in elderly patients, where the prevalence rate ranges 5%–78% depending on variations in countries, races, and study design [2,6,7]. The rates of taking more than 5 and 10 medications among Taiwanese elderly are 81% and 38%, respectively [8]. According to Taiwan's Nat ional Health Insurance Administration (NHIA) statistics, the medical expenditures for duplicate medications have exceeded US$1.2 million [9]. (Source: Computer Methods and P...
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Chang-Ming Chen, Li-Na Kuo, Kuei-Ju Cheng, Wan-Chen Shen, Kuan-Jen Bai, Chih-Chi Wang, Yi-Chun Chiang, Hsiang-Yin Chen Source Type: research

Computer-aided design, structural dynamics analysis, and in vitro susceptibility test of antibacterial peptides incorporating unnatural amino acids against microbial infections
Infectious diseases caused by new or previously unrecognized microorganisms are a major problem worldwide. Although the term became part of the journalist's lexicon in the 1990s, emerging infectious diseases have long been recognized as an important outcome of host –pathogen evolution. Because infections may have severe public health consequences, they are a focus of both the popular press and the scientific research [1]. In the past 70 years, antibiotics have been essential in the fight against infectious diseases and have been a contributing factor in the rise in life expectancy. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Yan Wang, Yong-Jian Yang, Ya-Na Chen, Hong-Yu Zhao, Shuai Zhang Source Type: research

Empirical search for factors affecting mean particle size of PLGA microspheres containing macromolecular drugs
Poly(lactic-co-glycolic acid) (PLGA) is one of the most attractive polymers used to manufacture many drug formulations, mainly due to its satisfactory safety profile and its ability to modify the drug dissolution profile for controlled-release formulations [1]. As an FDA-approved polymer, PLGA has been studied as a delivery vehicle for unstable active pharmaceutical ingredients (API) such as proteins, peptides, RNA, and DNA [2,3,4]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Jakub Szl ęk, Adam Pacławski, Raymond Lau, Renata Jachowicz, Pezhman Kazemi, Aleksander Mendyk Source Type: research

A robust image registration method based on total variation regularization under complex illumination changes
Image registration is the process of aligning two or more images of the same scene which may be taken at different times, from different viewpoints or by different sensors. Lots of novel approaches have been developed for this purpose. They can be classified into two categories: feature-based and area-based methods [1 –4]. The feature-based approaches consist of 3 steps: (1) extracting features from each image, (2) finding the correspondences between the extracted features using a similarity metric, and (3) estimating the transform parameters according to the locations of the corresponding points. (Source: Computer Metho...
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Khadijeh Aghajani, Mohammad T. Manzuri, Rohollah Yousefpour Source Type: research

A methodology based on openEHR archetypes and software agents for developing e-health applications reusing legacy systems
In most countries, the conventional healthcare model will soon become inadequate, due to the increasing healthcare costs for the growing population of elderly people, the rapid increase in chronic disease, the growing demand for new treatments and technologies, and the decrease in the number of health professionals relative to the population increase [1]. Recently, the United States Census Bureau estimated that the expected number of inhabitants in the United States older than 65 will be approximately 70 million in 2030, twice that in 2000 [2]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Jo ão Luís Cardoso de Moraes, Wanderley Lopes de Souza, Luís Ferreira Pires, Antonio Francisco do Prado Source Type: research