Computer Methods and Programs in Biomedicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Determinants and development of a web-based child mortality prediction model in resource-limited settings: A data mining approach
Child mortality is a core indicator for child health and well-being. In 2000, world leaders agreed on the Millennium Development Goals (MDGs) and called for reducing the Child mortality rate by two thirds between 1990 and 2015. This particular goal is known as the MDG 4 [1]. It refers to the death of infants and children under the age of five or between the ages of one month to four years. The global Child mortality rate dropped 53(50, 55) percent, from 91 (89, 92) deaths per 1,000 live births in 1990 to 43 (41, 46) in 2015. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 27, 2016 Category: Bioinformatics Authors: Brook Tesfaye, Suleman Atique, Noah Elias, Legesse Dibaba, Syed-Abdul Shabbir, Mihiretu Kebede Source Type: research

PCA Based Clustering for Brain Tumor Segmentation of T1w MRI Images
Brain tumor is a mass or a growth of abnormal cells in brain tissue. There are two types of tumors, cancerous and non-cancerous. Researches show that over a third of brain tumors are cancerous, and brain tumors rank among the top of cancer related deaths. Therefore, early diagnosis and treatment are crucial for survival [1]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 23, 2016 Category: Bioinformatics Authors: Irem Ers öz Kaya, Ayça Çakmak Pehlivanli, Emine Gezmez Sekizkardeş, Turgay Ibrikçi Source Type: research

Towards localization of malignant sites of asymmetry across bilateral mammograms
Mammography is the most cost-effective and accessible screening test available to diagnose breast cancer disease [1]. Bilateral asymmetry is defined as one of the four signs of breast cancer detectable by mammography by the American College of Radiography (ACR). Analysis of the asymmetry between the left and right mammograms may suggest the occurrence of tumorigenic changes at an early stage, when more evident signs of cancer are not yet present [2,3]. The transformation of a normal tissue into a malignant tumor, in fact, is a complex and multistage process, that typically requires a progression through a pre-cancerous les...
Source: Computer Methods and Programs in Biomedicine - November 22, 2016 Category: Bioinformatics Authors: P. Casti, A. Mencattini, M. Salmeri, A. Ancona, M. Lorusso, M.L. Pepe, C. Di Natale, E. Martinelli Source Type: research

Detecting Negation and Scope in Chinese Clinical Notes using Character and Word Embedding
An increasing amount of computerized clinical data is becoming available with the adoption of electronic medical records (EMR). Natural language processing (NLP) and information extraction (IE) techniques have been critical parts of the pipeline to automate the EMR data mining and knowledge discovery, and have become an active research field in biomedical informatics. For example, researchers have made significant progress on clinical named entity recognition (NER), which is to detect the boundaries and identify the categories of clinical entities, and map them to concepts in standardized terminologies [2-4]. (Source: Comp...
Source: Computer Methods and Programs in Biomedicine - November 22, 2016 Category: Bioinformatics Authors: Tian Kang, Shaodian Zhang, Nanfang Xu, Dong Wen, Xingting Zhang, Jianbo Lei Source Type: research

The OCarePlatform: A context-aware system to support independent living
There are many challenges involved in caring for the increasing number of elderly individuals and those with chronic illness in independent living facilities ( “residents”) [1]. One of these challenges is a shortage of skilled caregivers to provide help for residents [2] and a wide range of caregivers, some being formal (such as home nurses) and others being informal (such as neighbors). (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 17, 2016 Category: Bioinformatics Authors: F. De Backere, P. Bonte, S. Verstichel, F. Ongenae, F. De Turck Source Type: research

The OCarePlatform: A Context-aware Platform to support independent living
With an increasing number of elderly in our society and the shift from acute to chronic illness, the primary care systems in many countries are being overloaded. With this, many new challenges are placed in the forefront  [1]. One of the major challenges is the need for assistance in the home. Especially, with the reducing number of people able to provide care for their elderly or disabled relatives [2] and the wide range of different caregivers and organizations offering help to these people. Relatives, neighbors and acquaintances offering help will be further referred to as informal caregivers, while for example home n...
Source: Computer Methods and Programs in Biomedicine - November 17, 2016 Category: Bioinformatics Authors: F. De Backere, P. Bonte, S. Verstichel, F. Ongenae, F. De Turck Source Type: research

biomechZoo: An open-source toolbox for the processing, analysis, and visualization of biomechanical movement data
The field of movement science has a long history  [2], with the advent of the modern computer arguably providing the latest impetus for advances in our understanding of movement. Today, commercial motion capture data collection systems abound and are often packaged with software capable of computing standard biomechanical variables such as joint kinematics and kinetics. Popular examples are the Vicon (Vicon Motion Systems Ltd., Oxford, UK), Qualisys (Qualisys AB, Gotebörg, Sweden), and Motion Analysis (Motion Analysis Corp., Santa Rose, USA) systems. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 17, 2016 Category: Bioinformatics Authors: Philippe C. Dixon, Jonathan J. Loh, Yannick Michaud-Paquette, David J. Pearsall Source Type: research

Biopharmaceutics Data Management System for Anonymised Data Sharing and Curation: First Application with OrBiTo IMI Project
Over the last decade, drug development cost has increased exponentially [1], which led to the pharmaceutical industry together with academia and drug regulatory agencies, increasing efforts on “pre-competitive” research collaborations in various areas [2-4]. This research involves some lever of data sharing, but the disclosure of novel therapeutically active molecules’ attributes in an open database is in direct opposition to what gives the competitive advantages to the innovator de veloper. Some of the difficulties associated with full information disclosure are previously highlighted in other journal articles [5]. ...
Source: Computer Methods and Programs in Biomedicine - November 17, 2016 Category: Bioinformatics Authors: Kristin Lacy-Jones, Philip Hayward, Steve Andrews, Ian Gledhill, Mark McAllister, Bertil Abrahamsson, Amin Rostami-Hodjegan, Xavier Pepin Source Type: research

Evaluation of a smartphone-based assessment system in subjects with chronic ankle instability
• The smartphone-based assessment system can be used to provide quantitative determination of differences in postural control performance.• The smartphone-based assessment system can be used to discriminate the different postural control performance between sound leg and injured leg, and also be tween eyes-open and eyes-closed conditions.• Smartphone may have the potential to be a convenient, easy-used and valid tool for assessment of postural control ability on subjects with chronic ankle instability. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 10, 2016 Category: Bioinformatics Authors: Ya-Lan Chiu, Yi-Ju Tsai, Chueh-Ho Lin, You-Ruei Hou, Wen-Hsu Sung Source Type: research

Quantification of the first-order high-pass filter's influence on the automatic measurements of the electrocardiogram
This study shows a correlation relationship between the QRS integral (the main ECG signal part) and the ST-segment deviation (used for interpretation of acute myocardial infarction). We show significant differences between AC- and DC-coupled ECG recorded signals. As the work is based on clinical digital ECG records stored in raw format, the impact of this study for clinicians interpreting the ECG as well as technicians programming signal processing algorithms and expert systems performing the current automatic measurement and interpretation software is not negligible as believed today. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 9, 2016 Category: Bioinformatics Authors: Jonas Isaksen, Remo Leber, Ramun Schmid, Hans-Jakob Schmid, Gianluca Generali, Roger Ab ächerli Source Type: research

GIFT-Cloud: A data sharing and collaboration platform for medical imaging research
• A platform for sharing medical imaging data between clinicians and researchers• Extensible system connects three hospitals and two universities• Simple for end users with low impact on hospital IT systems• Automated anonymisation of pixel data and metadata at the clinical site• Maintains subject data groupings while preserving anonymity (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 9, 2016 Category: Bioinformatics Authors: Tom Doel, Dzhoshkun I. Shakir, Rosalind Pratt, Michael Aertsen, James Moggridge, Erwin Bellon, Anna L. David, Jan Deprest, Tom Vercauteren, S ébastien Ourselin Source Type: research

Automated characterization and counting of ki-67 protein for breast cancer prognosis: a quantitative immunohistochemistry approach
• Hybrid clustering using fuzzy C-means and k-means to segment Ki-67 nuclei.• Characterization of Ki-67 protein for assessing proliferation index.• Validation of methodology from the ground truth information.• Qualitative assessment of the proposed methodology using F-measure. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 7, 2016 Category: Bioinformatics Authors: Tushar Mungle, Suman Tewary, Indu Arun, Bijan Basak, Sanjit Agarwal, Rosina Ahmed, Sanjoy Chatterjee, Asok Kumar Maity, Chandan Chakraborty Source Type: research

Enhancement of lung sounds based on empirical mode decomposition and fourier transform algorithm
• A new lung sound enhancement technique is proposed based on EMD framework and prediction algorithm.• Heart sound locations in the lung sound signal are detected using Hilbert Heron Algorithm (HHA).• The missing values of lung sound signal are estimated using Fast Fourier Transform (FFT) base d prediction algorithm.• The proposed method gives a superior performance than the baseline method. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 3, 2016 Category: Bioinformatics Authors: Ashok Mondal, Poulami Banerjee, Ajay Somkuwar Source Type: research

An anomaly detection approach for the identification of DME patients using spectral domain optical coherence tomography images
• A method to detect abnormal B-scans in SD-OCT volumes• An anomaly detection approach for classification of SD-OCT volumes• High sensitivity and specificity compared to other supervised classification methods (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - November 3, 2016 Category: Bioinformatics Authors: D ésiré Sidibé, Shrinivasan Sankar, Guillaume Lemaître, Mojdeh Rastgoo, Joan Massich, Carol. Y. Cheung, Gavin S.W. Tan, Dan Milea, Ecosse Lamoureux, Tien Y. Wong, Fabrice Mériaudeau Source Type: research

Bio-mathematical analysis for the peristaltic flow of single wall carbon nanotubes under the impact of variable viscosity and wall properties
• Exact solution is calculated for the temperature and for the velocity profile.• Temperature profile decreases when we add nanoparticles in our base fluid basically, higher thermal conductivity of the nano particle plays a key role for the quick dissipation this justifies that the use of single wall carbon nanotube in different type as coolant• Increase in stiffness and Grashof number in the channel contributes to decrease in fluid velocity.• Symmetry of the curved channel destroys due to the curvedness for velocity, temperature and for contour plots. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - October 31, 2016 Category: Bioinformatics Authors: Iqra Shahzadi, Hina Sadaf, Sohail Nadeem, Anber Saleem Source Type: research