Automated characterization and counting of ki-67 protein for breast cancer prognosis: a quantitative immunohistochemistry approach

• Hybrid clustering using fuzzy C-means and k-means to segment Ki-67 nuclei.• Characterization of Ki-67 protein for assessing proliferation index.• Validation of methodology from the ground truth information.• Qualitative assessment of the proposed methodology using F-measure.

Source: Computer Methods and Programs in Biomedicine - November 7, 2016 Category: Bioinformatics Authors: Tushar Mungle, Suman Tewary, Indu Arun, Bijan Basak, Sanjit Agarwal, Rosina Ahmed, Sanjoy Chatterjee, Asok Kumar Maity, Chandan Chakraborty Source Type: research