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Mask_explorer: A tool for exploring brain masks in fMRI group analysis
Functional magnetic resonance imaging (fMRI) is widely used in neuroscience research. The increasing number of papers related to fMRI proves that this technique remains a subject of interest. Many types of fMRI experiments and analyses can be used to infer knowledge about the brain in health or disease. Single-subject statistics is a method of obtaining subject-specific information; this is the first step for other type of analyses. However, testing hypotheses related to a population of subjects (second-level or group-level statistics) is typically the goal of most neuroscience studies. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Martin Gajdo š, Michal Mikl, Radek Mareček Source Type: research

Prediction of G-protein coupled receptors and their subfamilies by incorporating various sequence features into Chou's general PseAAC
G-protein coupled receptors (GPCRs) are seven-transmembrane domain receptors that sense molecules outside the cell and activate inside signal transduction pathways for cellular responses. These are called seven-transmembrane receptors because they pass through the cell membrane seven times. G-protein coupled receptors can be grouped into six classes based on sequence homology and functional similarity; these are Class A (Rhodopsin-like), Class B (Secretin like), Class C (Metabotropic glutamate), Class D (cyclic AMP), Class E (Taste), and Class F (Vomeronasal) receptors. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Arvind Kumar Tiwari Source Type: research

Prediction of nocturnal hypoglycemia by an aggregation of previously known prediction approaches: proof of concept for clinical application
According to a report of a Workgroup of the American Diabetes Association and the Endocrine Society [1] hypoglycemia is defined as blood glucose (BG) level less than 70  mg/dL. Nocturnal hypoglycemia (NH) is the most feared type of hypoglycemia in patients with diabetes treated by insulin. Due to its time of occurrence, it is usually asymptomatic [2,3] but has negative impact on patients' health. NH problem is less worrisome for patients equipped with Continuous Glucose Monitors (CGM), especially when they are combined with other sensors that can be used for detecting NH, such as electrocardiogram (ECG) sensors [4] or el...
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Pavlo Tkachenko, Galyna Kriukova, Marharyta Aleksandrova, Oleg Chertov, Eric Renard, Sergei V. Pereverzyev Source Type: research

A new thresholding technique based on fuzzy set as an application to leukocyte nucleus segmentation
Segmentation is crucial in the field of computer vision. Various algorithms are available in literature for segmentation of micro array images [1], breast images [2,3] and skin images [4] and so on. Immune system protects the body from harmful bacteria, viruses and other pathogens by finding and eliminating them. Leukocytes are the primary constituent in the immune system and play a vital role in identifying and destroying while there is a pathogenic intrusion into the body. These cells are originated from a multi-potent cell in bone marrow. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: V.P. Ananthi, P. Balasubramaniam Source Type: research

Computerized breast cancer analysis system using three stage semi-supervised learning method
• The abundance of available unlabeled data can be used in this scheme.• We developed data weighing module and redesigned similarity function.• We designed and combined local features and global features together.• Our system has acceptable sensitivity even at a low false positive rate. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Wenqing Sun, Tzu-Liang (Bill) Tseng, Jianying Zhang, Wei Qian Source Type: research

Effect of infusion tests on the dynamical properties of intracranial pressure in hydrocephalus
• Wavelet turbulence and entropy revealed changes in the ICP signals during ITs.• Changes in similarity, irregularity and variability of ICP signals were found.• Significant differences in B2 can be related to ICP pulse waves.• Only slight differences were found in B1, associated with ICP respiratory waves. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: María García Gadañón, Jesús Poza, Alejandro Bachiller, David Santamarta, Roberto Hornero Source Type: research

An immune-inspired semi-supervised algorithm for breast cancer diagnosis
• In this paper, we seamlessly integrate the state-of-the-art in life science and artificial intelligence, and investigate a semi-supervised learning algorithm to reduce the need for labeled data. In the proposed algorithm, the Kent chaotic helps to search the best solution in the whole antibody cells feature vector space. Considering that the value of k is sensitive to the experiment results, we use the weighted k nearest neighbor algorithm to diagnose the breast cancer.• We used two well-known benchmark breast cancer datasets in our study, which were acquired from the UCI machine learning repository. (Source: Compute...
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Lingxi Peng, Wenbin Chen, Wubai Zhou, Fufang Li, Jin Yang, Jiandong Zhang Source Type: research

Five Multiresolution-based Calcium Volume Measurement Techniques from Coronary IVUS Videos: A Comparative Approach
Fast intravascular ultrasound (IVUS) video processing is required for calcium volume computation during the planning phase of percutaneous coronary interventional (PCI) procedures. Nonlinear multiresolution techniques are generally applied to improve the processing time by down-sampling the video frames. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Sumit K. Banchhor, Tadashi Araki, Narendra D. Londhe, Nobutaka Ikeda, Petia Radeva, Ayman Elbaz, Luca Saba, Andrew Nicolaides, Shoaib Shafique, John R. Laird, Jasjit S. Suri Source Type: research

Mask_explorer: a tool for exploring brain masks in fMRI group analysis
• We found, that interface for exploration of optimal volumes of interest is missing.• We developed tool the mask_explorer, freely available with graphical user interface.• Tool for quick validation of the group fMRI analysis space is described.• Practical examples with crucial role of the mask_explorer are shown.• Usage of mask_explorer before group fMRI analysis is recommended. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Martin Gajdoš, Michal Mikl, Radek Mareček Source Type: research

MirrARbilitation: a clinically-related gesture recognition interactive tool for an AR rehabilitation system.
• Biomechanics techniques brings high applicability and therapist familiarity• Interaction using specific therapeutic movements improves therapeutic efficacy• Gesture recognition enables guidance and instruction to correct movements• Biomechanical standards to recognize movements is valuable in guiding users• MirrARbilitation improves exercise engagement and performance quality (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Alana Elza Fontes Da Gama, Pasca Fallavollita, Thiago Menezes Chaves, Lucas Silva Figueiredo, Adriana Baltar, Ma Meng, Nassir Navab, Veronica Teichrieb Source Type: research

Prediction of G-protein coupled receptors and their subfamilies by incorporating various sequence features into chou's general pseaac
• In this paper the protein samples are represented by eight sequence derived properties• In this paper the amino acid composition, dipeptide composition, correlation features, composition, transition, distribution, sequence order descriptors and pseudo amino acid composition with total 1497 number of sequence derived features are used• Here a weighted k –nearest neighbor classifier are proposed to use with UNION of best 50 features selected by Fisher score based feature selection, ReliefF, fast correlation based filter, minimum redundancy maximum relevancy and support vector machine based recursive feature elimina...
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Arvind Kumar Tiwari Source Type: research

Prediction of nocturnal hypoglycemia by an aggregation of previously known prediction approaches: proof of concept for clinical application
• We propose a method of combining several predictors into a new one that will perform at the level of the best involved one, or even outperform all individual candidates.• Portability of the method. This feature of the method allows its simple implementation in the form of a diabetic Smartphone app.• The potential for everyday use by any patient who performs self-monitoring of blood glucose.• The idea is based on the linear functional strategy for regularized ranking. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: Pavlo Tkachenko, Galyna Kriukova, Marharyta Aleksandrova, Oleg Chertov, Eric Renard, Sergei V. Pereverzyev Source Type: research

A new thresholding technique based on fuzzy set as an application to leukocyte nucleus segmentation
• A new fuzzy method is introduced to segment leukocytes in blood smear images.• Interval-valued intuitionistic fuzzy set is generated by minimizing ultrafuzziness.• Similarity between ideally thresholded and the segmented images are computed.• Best threshold is obtained by maximizing similarity.• Experimentally proven that the proposed method is better than other fuzzy methods. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: V.P. Ananthi, P. Balasubramaniam Source Type: research

Effects of slip and convective conditions on the peristaltic flow of couple stress fluid in an asymmetric channel through porous medium
• The peristaltic flow of couple stress fluid in an asymmetric channel through porous medium with heat transfer is studied.• The effects of slip and convective conditions are also considered.• Six types of different wave forms are considered for the analysis.• The effects of different flow parameters are discussed through graphs.• The comparison is made for Newtonian fluid and couple stress fluid models. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 7, 2016 Category: Bioinformatics Authors: K. Ramesh Source Type: research

Sector mapping method for 3D detached retina visualization
The main surgical repair options for retinal detachment include pneumatic retinopexy, scleral buckling, pars plana vitrectomy, and combined pars plana vitrectomy and scleral buckle [1 –3]. The suitability of a repair option and the effectiveness of an operation highly depend on the accurate location of the retinal detachment. However, it is hard to clearly observe the whole retina because it is attached to the inside of the eyeball, and doctors commonly observe a part of the re tina through the pupil using an ophthalmoscope or other medical instrument. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - July 5, 2016 Category: Bioinformatics Authors: Yi-Ran Zhai, Yong Zhao, Jie Zhong, Ke Li, Cui-xin Lu, Bing Zhang Source Type: research