Predicting Return Visits to the Emergency Department for Pediatric Patients: Applying Supervised Learning Techniques to the Taiwan National Health Insurance Research Database
The emergency department (ED) is a critical medical resource in delivering emergency services. Clinicians must make rapid decisions to ensure patients are treated promptly. Medical errors are thus inevitable because of the complex processes and busy work environments within EDs [1,2]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 25, 2017 Category: Bioinformatics Authors: Ya-Han Hu, Chun-Tien Tai, Solomon Chih-Cheng Chen, Hai-Wei Lee, Sheng-Feng Sung Source Type: research

A Novel Method for Planning Liver Resections Using Deformable B ézier Surfaces and Distance Maps
Background and Objective: For more than a decade, computer-assisted surgical systems have been helping surgeons to plan liver resections. The most widespread strategies to plan liver resections are: drawing traces in individual 2D slices, and using a 3D deformable plane. In this work, we propose a novel method which requires low level of user interaction while keeping high flexibility to specify resections. Methods: Our method is based on the use of B ézier surfaces, which can be deformed using a grid of control points, and distance maps as a base to compute and visualize resection margins (indicators of safety) in real-t...
Source: Computer Methods and Programs in Biomedicine - March 24, 2017 Category: Bioinformatics Authors: Rafael Palomar, Faouzi A. Cheikh, Bj ørn Edwin, Åsmund Fretland, Azeddine Beghdadi, Ole J. Elle Source Type: research

A two-step Convolutional Neural Network based Computer-aided detection scheme for automatically segmenting adipose tissue volume depicting on CT images
Abdominal obesity is one of the most prevalent public health problems and over one third of adults were obese in the United States in recent years [1]. Obesity is strongly associated with many different diseases such as heart diseases, metabolic disorders, type 2 diabetes and certain types of cancers [1 –3]. Inside a human body, there are subcutaneous fat areas (SFA) and visceral fat areas (VFA), which both contribute to the abdominal obesity. Studies have shown that in the clinical practice separate measurement or quantification of subtypes of adipose tissue in SFA and VFA is crucial for obesity assessment since viscera...
Source: Computer Methods and Programs in Biomedicine - March 21, 2017 Category: Bioinformatics Authors: Yunzhi Wang, Yuchen Qiu, Theresa Thai, Kathleen Moore, Hong Liu, Bin Zheng Source Type: research

Modeling and control of operator functional state in a unified framework of fuzzy inference petri nets
Adaptive Automation (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 20, 2017 Category: Bioinformatics Authors: Jian-Hua Zhang, Jia-Jun Xia, Jonathan M. Garibaldi, Petros P. Groumpos, Ru-Bin Wang Source Type: research

Fuzzy Modeling and Control of Operator Functional State in a Unified Framework of Fuzzy Inference Petri Nets
Adaptive Automation (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 19, 2017 Category: Bioinformatics Authors: Jian-Hua Zhang, Jia-Jun Xia, Jonathan M. Garibaldi, Petros P. Groumpos, Ru-Bin Wang Source Type: research

A Fully Automatic Approach for Multimodal PET and MR Image Segmentation in Gamma Knife Treatment Planning
Leksell Gamma Knife ® (Elekta, Stockholm, Sweden) is a stereotactic radiosurgical device to treat different brain disorders that are often inaccessible for conventional surgery, such as benign or malignant tumors, arteriovenous malformations and trigeminal neuralgia [1,2]. Stereotactic radiosurgery allows an accurate external irradiation (with a single, high dose and steep dose gradient) to minimize doses given to adjacent critical brain structures. The gamma rays (generated by Cobalt-60 [60Co] radioactive sources) are focused on the target through a metal helmet. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 18, 2017 Category: Bioinformatics Authors: Leonardo Rundo, Alessandro Stefano, Carmelo Militello, Giorgio Russo, Maria Gabriella Sabini, Corrado D'Arrigo, Francesco Marletta, Massimo Ippolito, Giancarlo Mauri, Salvatore Vitabile, Maria Carla Gilardi Source Type: research

E-Health Internationalization Requirements for Audit Purposes
E-health is a process that provides health care information via electronic means and connects patients, physicians, care providers, health care delivery systems, citizens, governments and regulatory bodies through the use of information and telecommunication technologies, particularly over the Internet. The Internet has the scope, the infrastructure, and the acceptance to achieve widespread change and to drive the development and adoption of e-health applications [1]. e-health programs provide the potential for: enhanced reach at a relatively low cost; scalability; time efficiency; and the capacity to provide individual pa...
Source: Computer Methods and Programs in Biomedicine - March 17, 2017 Category: Bioinformatics Authors: Sofia Ouhbi, Jos é Luis Fernández-Alemán, Juan Manuel Carrillo-de-Gea, Ambrosio Toval, Ali Idri Source Type: research

Optimized PID control of depth of hypnosis in anesthesia
The application of feedback control to drug dosing problems has been largely investigated in the last years (see, for example, [1]) because of the inherent socio-economic benefits. In particular, closing the loop in general anesthesia proved to be highly beneficial in reducing costs for both patient and society at large. In fact, the use of an automatic control system might provide significant benefits such as a reduction of the workload of the anesthesiologist (who has in any case to be present with a supervisory role), a reduction of the amount of drug used (which implies a faster and better recovery time of the patient ...
Source: Computer Methods and Programs in Biomedicine - March 17, 2017 Category: Bioinformatics Authors: Fabrizio Padula, Clara Ionescu, Nicola Latronico, Massimiliano Paltenghi, Antonio Visioli, Giulio Vivacqua Source Type: research

A Lightweight QRS Detector for Single Lead ECG Signals using a Max-Min Difference Algorithm
Electrocardiogram (ECG) represents the myocardial electrical activities of the heart. ECG signals play a significant role in the diagnosis of cardiovascular diseases, such as cardiac arrhythmias, hypertension or ischaemic heart diseases. ECG recordings used to be a time consuming process, and require the examination by on-site cardiologists to detect and diagnose various heart conditions. Nowadays, mobile ECG sensors, such as the Shimmer or Alivecor ® sensors [1], are available. These sensors not only are easy to use, but also are affordable and efficient in acquiring ECG readings. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 17, 2017 Category: Bioinformatics Authors: Diptangshu Pandit, Li Zhang, Chengyu Liu, Samiran Chattopadhyay, Nauman Aslam, Chee Peng Lim Source Type: research

Developing a Ubiquitous Health Management System with Healthy Diet Control for Metabolic Syndrome Healthcare in Taiwan
“An ounce of prevention is worth a pound of cure – by Benjamin Franklin.” Many prior studies for healthcare encouraged the self-health management programs of chronic diseases to improve health status of patients and reduce financial cost of hospitalization [1–3]. Those programs educated the patients in prevention knowledge and healthcare skills of perceived illness for diet control, medication care, behavior measurement, risk assessment, etc. [4]. They achieved the ubiquitous health management system (UHMS), which involves electronic, internet, or mobile interface in a computerized arc hitecture, for the patients t...
Source: Computer Methods and Programs in Biomedicine - March 17, 2017 Category: Bioinformatics Authors: Yao-Chiang Kan, Kai-Hong Chen, Hsueh-Chun Lin Source Type: research

Robust Activation Detection Methods for Real-Time and Offline fMRI Analysis
Magnetic resonance imaging (MRI) is a widely used technique for high resolution views of three dimensional structural images of living tissues. Functional MRI (fMRI), on the other hand, is a mode of MR imaging where the focus is on the oxygen levels in the blood, called Blood Oxygen Level Dependent (BOLD) contrast [20]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 17, 2017 Category: Bioinformatics Authors: Kaya Oguz, Muhammed G. Cinsdikici, Ali Saffet Gonul Source Type: research

Multiple model predictive control for optimal drug administration of mixed immunotherapy and chemotherapy of tumours
Since cancer is the second cause of death worldwide, many researchers mainly focus on the modelling and treatment of cancer. Currently, some crucial clinical practices have been performed to determine abnormal conditions, especially tumours and cancers [1]. Also, pathologists are used to distinguish between structure and function in tissues, and, thus, they describe a general approach of how to derive biological functions from structures [2]. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 14, 2017 Category: Bioinformatics Authors: N. Sharifi, S. Ozgoli, A. Ramezani Source Type: research

AntibiogramJ: a Tool for Analysing Images from Disk Diffusion Tests
Determining the antimicrobial susceptibility of microorganisms is of great importance in clinical microbiology not only to guide therapeutic decisions in infectious diseases, but also to investigate the evolution and epidemiology of resistance  [1] — which is essential for implementing hospital prevention programs. Antimicrobial susceptibility tests are used to examine the in vitro activity of different antimicrobial agents against a specific microorganism. There are a variety of methods for determining antimicrobial susceptibility, in cluding disk diffusion, agar dilution or broth microdilution. (Source: Computer Metho...
Source: Computer Methods and Programs in Biomedicine - March 11, 2017 Category: Bioinformatics Authors: C.A. Alonso, C. Dom ínguez, J. Heras, E. Mata, V. Pascual, C. Torres, M. Zarazaga Source Type: research

A comparison between swallowing sounds and vibrations in patients with dysphagia
Cervical auscultation (CA), the observation of swallowing sounds or vibrations during deglutition, has been used in the screening of swallowing disorders [1 –10]. The acoustic information observed during swallowing has not yet been clearly delineated to represent specific physiologic events occurring during swallowing because the signals are so complex, and numerous events are taking place simultaneously during a single swallow. In CA, a stethoscope o r an electronic acoustic/vibratory detector, such as a microphone or an accelerometer, is placed on the patient’s anterior neck on the skin in the region of the larynx to...
Source: Computer Methods and Programs in Biomedicine - March 9, 2017 Category: Bioinformatics Authors: Faezeh Movahedi, Atsuko Kurosu, James L. Coyle, Subashan Perera, Ervin Sejdi ć Source Type: research

A PC-based shutter glasses controller for visual stimulation using multithreading in LabWindows/CVI
In newborn children, the nerves and brain function that control eye movement and image processing are still developing. If sufficient binocular function is not achieved in the first several months of life, the eyes can drift out of alignment, most commonly crossing inward. This eye misalignment prevents the brain from receiving the aligned images needed for binocular depth perception. Another abnormality, namely different refractive error between the two eyes, causes blurred vision in one eye because human eyes cannot focus independently. (Source: Computer Methods and Programs in Biomedicine)
Source: Computer Methods and Programs in Biomedicine - March 9, 2017 Category: Bioinformatics Authors: Ivan Gramatikov, Kurt Simons, David Guyton, Boris Gramatikov Source Type: research