Formulas for fixing serum sodium: curb your enthusiasm
A variety of formulas have been proposed to predict changes in serum sodium concentration. All are based on an experiment done over 50 years ago by Edelman, who derived a formula relating the plasma sodium concentration to isotopically measured body sodium, potassium, and water. Some of these formulas fail because they do not include urinary losses of electrolytes and water. Even those that include these essential variables are not accurate enough for clinical use because it is impractical to adjust calculations to rapid changes in urinary composition, and because the formulas do not account for changes in serum sodium cau...
Source: CKJ: Clinical Kidney Journal - July 21, 2016 Category: Urology & Nephrology Authors: Sterns, R. H. Tags: ELECTROLYTES Source Type: research
Announcements
(Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Tags: ANNOUNCEMENTS Source Type: research
Improving clinical skills to support the emotional and psychological well-being of patients with end-stage renal disease: a qualitative evaluation of two interventions
Conclusions
These qualitative study findings suggest that both interventions are feasible and acceptable and have the potential to help consultants improve emotional and psychological patient care, providing cognitive and behavioural tools to enable discussion of emotional issues during routine outpatient consultations. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Taylor, F., Combes, G., Hare, J. Tags: PSYCHOSOCIAL ISSUES Source Type: research
Caregiver word reading literacy and health outcomes among children treated in a pediatric nephrology practice
Conclusions
Low caregiver functional word reading literacy was negatively related to health outcomes of adolescents with CKD/ESKD as reflected by greater ER visits. Educational materials and teaching strategies (dialysis training protocols, patient education materials) adjusted for low literacy levels may contribute to better outcomes. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Rak, E. C., Hooper, S. R., Belsante, M. J., Burnett, O., Layton, B., Tauer, D., Mantoo, B., DeWalt, D., Ferris, M. E. Tags: PSYCHOSOCIAL ISSUES Source Type: research
Differences in emotional responses in living and deceased donor kidney transplant patients
Conclusions
Feelings of guilt and anxiety may be an important focus for interventions to improve emotional adjustment to transplantation, especially in LD recipients. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Zimmermann, T., Pabst, S., Bertram, A., Schiffer, M., de Zwaan, M. Tags: PSYCHOSOCIAL ISSUES Source Type: research
Patient's perceptions of chronic kidney disease and their association with psychosocial and clinical outcomes: a narrative review
Patients with chronic kidney disease (CKD) form organized beliefs regarding their illness and treatment. These perceptions influence the coping strategies employed by an individual to manage his/her illness and may act as a predictor for his/her willingness to engage in self-management behaviours. While illness perceptions have been identified as predictors of non-adherence, depression and mortality in dialysis patients, there is a paucity of research in CKD patients not requiring renal replacement therapy. This narrative review synthesizes the existing literature regarding the role of illness perceptions and associated cl...
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Clarke, A. L., Yates, T., Smith, A. C., Chilcot, J. Tags: PSYCHOSOCIAL ISSUES Source Type: research
Dialyzing women and men: does it matter? An observational study
Conclusions
Many parameters differ significantly between female and male dialysis patients. Considering the effects of sex on several parameters may be a valuable approach for achieving better outcomes when formulating treatment strategies in this patient population. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Artan, A. S., Kircelli, F., Ok, E., Yilmaz, M., Asci, G., Dogan, C., Oto, O., Gunestepe, K., Basci, A., Sever, M. S. Tags: DIALYSIS Source Type: research
Sevelamer carbonate reduces the risk of hypomagnesemia in hemodialysis-requiring end-stage renal disease patients
Conclusions
Hemodialysis patients receiving sevelamer show higher serum magnesium levels and a reduced risk of hypomagnesemia. This effect remains even after adjustment for PPI use. This effect could contribute to the still controversial superiority of sevelamer in preventing vascular calcifications. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Rosa-Diez, G., Negri, A. L., Crucelegui, M. S., Philippi, R., Perez-Teysseyre, H., Sarabia-Reyes, C., Loor-Navarrete, H., Heguilen, R. Tags: DIALYSIS Source Type: research
Comparison of Turkish and US haemodialysis patient mortality rates: an observational cohort study
Conclusions
The annual mortality rate of prevalent HD patients was found to be significantly lower in the studied Turkish cohort compared with that published by the US Renal Data System Annual Data Report. Differences in practice patterns may contribute to the divergence. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Asci, G., Marcelli, D., Celtik, A., Grassmann, A., Gunestepe, K., Yaprak, M., Tamer, A. F., Turan, M. N., Sever, M. S., Ok, E. Tags: DIALYSIS Source Type: research
A study to describe the health trajectory of patients with advanced renal disease who choose not to receive dialysis
Conclusions
We have shown there is a significant decline in functional status in the last 6 months before death in the CM population. Of interest, there was a significant relationship of lower serum albumin with functional decline and risk of death. We hope that with improved insight into disease trajectories we can improve our ability to identify and respond to the changes in needs of these patients, facilitate complex and sensitive end-of-life discussions and improve end-of-life care. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Kilshaw, L., Sammut, H., Asher, R., Williams, P., Saxena, R., Howse, M. Tags: END-STAGE KIDNEY DISEASE Source Type: research
Renal replacement therapy in Europe: a summary of the 2013 ERA-EDTA Registry Annual Report with a focus on diabetes mellitus
This article provides a summary of the 2013 European Renal Association–European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report (available at http://www.era-edta-reg.org), with a focus on patients with diabetes mellitus (DM) as the cause of end-stage renal disease (ESRD).
Methods
In 2015, the ERA-EDTA Registry received data on renal replacement therapy (RRT) for ESRD from 49 national or regional renal registries in 34 countries in Europe and bordering the Mediterranean Sea. Individual patient data were provided by 31 registries, while 18 registries provided aggregated data. The total population...
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Kramer, A., Pippias, M., Stel, V. S., Bonthuis, M., Abad Diez, J. M., Afentakis, N., Alonso de la Torre, R., Ambuhl, P., Bikbov, B., Bouzas Caamano, E., Bubic, I., Buturovic-Ponikvar, J., Caskey, F. J., Castro de la Nuez, P., Cernevskis, H., Collart, F., Tags: END-STAGE KIDNEY DISEASE Source Type: research
Diabetes mellitus as a cause of end-stage renal disease in Europe: signs of improvement
(Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: van den Brand, J. A. J. G. Tags: END-STAGE KIDNEY DISEASE Source Type: research
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling
Conclusions
In patients of EA with CKD (CRIC cohort), we found striking associations between uric acid and SNPs on ABCG2, a key transporter of uric acid by intestine. Compared with ABCG2, SLC2A9 played a much less significant role in this subset of patients with CKD. SNPs in other SLC (e.g. SLC22A8 or OAT3) and ABC (e.g. ABCC4 or MRP4) genes appear to make a weak gender-dependent contribution to uric acid homeostasis in CKD. As renal urate transport is affected in the setting of declining kidney function, extra-renal ABCG2 appears to play a compensatory role—a notion consistent with animal studies and the Remote Sens...
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Bhatnagar, V., Richard, E. L., Wu, W., Nievergelt, C. M., Lipkowitz, M. S., Jeff, J., Maihofer, A. X., Nigam, S. K. Tags: CHRONIC KIDNEY DISEASE Source Type: research
High prevalence of chronic kidney disease in a semi-urban population of Western India
Conclusions
The prevalence of CKD in a semi-urban apparently healthy Indian population was higher than the reported prevalence in developed countries. Significant differences between regions point to the need to evaluate and correctregion-specific risk factors. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Trivedi, H., Vanikar, A., Patel, H., Kanodia, K., Kute, V., Nigam, L., Suthar, K., Thakkar, U., Sutariya, H., Gandhi, S. Tags: CHRONIC KIDNEY DISEASE Source Type: research
Incident chronic kidney disease: trends in management and outcomes
Conclusion
In this integrated health care system, management of incident CKD over the past decade has intensified. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - May 30, 2016 Category: Urology & Nephrology Authors: Perkins, R. M., Chang, A. R., Wood, K. E., Coresh, J., Matsushita, K., Grams, M. Tags: CHRONIC KIDNEY DISEASE Source Type: research
