A neglected issue in dialysis practice: haemodialysate
In conclusion, learning about the art and the science of fashioning haemodialysates is one of the best ways to further the understanding of the pathophysiologic processes underlying myriad acid–base, fluid, electrolyte as well as blood pressure abnormalities of the uraemic patient on maintenance haemodialysis. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Basile, C., Lomonte, C. Tags: HAEMODIALYSIS Source Type: research
Kinetics of serum 25-hydroxyvitamin D in haemodialysis patients treated with monthly oral cholecalciferol
Conclusion
The oral administration of 100 000 IU CCF once a month maintains a normal serum level in 90% of HD patients. Serum 25-D level reaches a plateau level after 12 weeks of therapy. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Jean, G., Souberbielle, J.-C., Lechevallier, S., Chazot, C. Tags: HAEMODIALYSIS Source Type: research
Usefulness and feasibility of measuring ionized calcium in haemodialysis patients
Conclusion
In the present study, we report that (1) delayed ICa measure is feasible in dialysis patients using a freezing technique, (2) hypocalcaemia is highly prevalent in HD patients and poorly predicted by Alb-Ca level, (3) the main factor associated with ICa level is sex of the individual and (4) calcaemia is not associated with survival rate using any of the three methods. (Source: CKJ: Clinical Kidney Journal)
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Jean, G., Granjon, S., Zaoui, E., Deleaval, P., Hurot, J.-M., Lorriaux, C., Mayor, B., Chazot, C. Tags: HAEMODIALYSIS Source Type: research
Lactate clearance and metabolic aspects of continuous high-volume hemofiltration
We report a 28-year-old Caucasian male with a history of hemophagocytic lymphohistiocytosis who presented with septic shock, severe lactic acidosis and multiple organ failure. Metabolic acidosis was corrected after bicarbonate therapy and CRRT with a hemofiltration rate of 7 L/h (58 mL/kg/h). Lactate clearance was calculated to be 79 mL/min. Compared with reported rates of lactate overproduction in septic shock, the rate of lactate clearance is quite small. Our case suggests that CRRT with high-volume hemofiltration is not effective for severe lactic acidosis. Lactic acidosis alone should not be considered as a nonrenal in...
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Cheungpasitporn, W., Zand, L., Dillon, J. J., Qian, Q., Leung, N. Tags: HAEMODIALYSIS Source Type: research
High convection volume in online post-dilution haemodiafiltration: relevance, safety and costs
Increasing evidence suggests that treatment with online post-dilution haemodiafiltration (HDF) improves clinical outcome in patients with end-stage kidney disease, if compared with haemodialysis (HD). Although the primary analyses of three large randomized controlled trials (RCTs) showed inconclusive results, post hoc analyses of these and previous observational studies comparing online post-dilution HDF with HD showed that the risk of overall and cardiovascular mortality is lowest in patients who are treated with high-volume HDF. As such, the magnitude of the convection volume seems crucial and can be considered as the &l...
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Mostovaya, I. M., Grooteman, M. P. C., Basile, C., Davenport, A., de Roij van Zuijdewijn, C. L. M., Wanner, C., Nube, M. J., Blankestijn, P. J., on behalf of the EuDial group Tags: HAEMODIALYSIS Source Type: research
Aneurysms and pseudoaneurysms in dialysis access
Aneurysms are a common and often difficult complication seen with arteriovenous vascular access for haemodialysis. The purpose of this narrative review is to define and describe the scale of the problem and suggested therapeutic strategies. A narrative review of the published literature illustrated by individual cases is presented with the aim of summarising the relevant literature. The definitions of aneurysm are inconsistent throughout the literature and therefore systematic review is impossible. They vary from qualitative descriptions to quantitative definitions using absolute size, relative size and also size plus char...
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Mudoni, A., Cornacchiari, M., Gallieni, M., Guastoni, C., McGrogan, D., Logias, F., Ferramosca, E., Mereghetti, M., Inston, N. Tags: HAEMODIALYSIS Source Type: research
Uraemic toxins and new methods to control their accumulation: game changers for the concept of dialysis adequacy
The current concept of an adequate dialysis based only on the dialysis process itself is rather limited. We now have considerable knowledge of uraemic toxicity and improved tools for limiting uraemic toxin accumulation. It is time to make use of these. A broader concept of adequacy that focusses on uraemic toxicity is required. As discussed in the present review, adequacy could be achieved by many different methods in combination with, or instead of, dialysis. These include preservation of renal function, dietary intake, reducing uraemic toxin generation rate and intestinal absorption, isolated ultrafiltration and extracor...
Source: CKJ: Clinical Kidney Journal - July 27, 2015 Category: Urology & Nephrology Authors: Glorieux, G., Tattersall, J. Tags: HAEMODIALYSIS Source Type: research
