Biochemical and hematological changes among anemic and non-anemic pregnant women attending antenatal clinic at the Bolgatanga regional hospital, Ghana
ConclusionAnemic pregnant women are associated with a significant derangement in hematological and iron indices that implicate iron deficiency. This was influenced by hemoglobinopathies and parasitic infections. (Source: BMC Hematology)
Source: BMC Hematology - September 17, 2018 Category: Hematology Source Type: research

The clinical presentation, utilization, and outcome of individuals with sickle cell anaemia presenting to urban emergency department of a tertiary hospital in Tanzania
ConclusionsWe described the clinical presentation, management, and outcomes of patients with SCA presenting to the largest public ED in Tanzania, as well as information on resource utilization. This information can inform development of treatment guidelines, clinical staff education, and clinical research aimed at optimizing care for SCA patients. (Source: BMC Hematology)
Source: BMC Hematology - September 17, 2018 Category: Hematology Source Type: research

Seroprevalence and trends of transfusion transmitted infections at Harar blood bank in Harari regional state, Eastern Ethiopia: eight years retrospective study
ConclusionsThe magnitude of transfusion transmitted infections was lower than the previous studies conducted in Ethiopia. However, the decline in trends of transfusion transmitted infections has not been significant for some pathogens. Therefore, strict adherence with the criteria of preliminary blood donor selection should be implemented to reduce the amount of blood being withdrawn from transfusion after collection and screening. (Source: BMC Hematology)
Source: BMC Hematology - September 15, 2018 Category: Hematology Source Type: research

Albumin, copper, manganese and cobalt levels in children suffering from sickle cell anemia at Kasumbalesa, in Democratic Republic of Congo
ConclusionIn our study, albumin, manganese, cobalt and copper values did not differ between SCA children in steady state and Hb-AA children. The lack of differences in plasma elemental concentrations between the two groups in context of increased demands in the SCA group, may represent adequate compensatory intake or elemental dyshomeostasis in the SCA group. (Source: BMC Hematology)
Source: BMC Hematology - September 6, 2018 Category: Hematology Source Type: research

Evaluation and characterization of tumor lysis syndrome before and after chemotherapy among pediatric oncology patients in Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia
ConclusionThere was high incidence of TLS irrespective of socio-demographic variation among study participants, suggesting that children with cancer are at risk of developing TLS. As TLS is a life-threatening complication of malignancies, early identification of patients at risk and reducing morbidity and mortality is crucially important. (Source: BMC Hematology)
Source: BMC Hematology - September 4, 2018 Category: Hematology Source Type: research

A new adult AML case with an extremely complex karyotype, remission and relapse combined with high hyperdiploidy of a normal chromosome set in secondary AML
ConclusionsTo the best of our knowledge, a comparable adult AML associated with such a CK, coexistence of 3q rearrangements with loss ofTP53 at diagnosis, and HH in secondary AML were not previously reported. Thus, the combination of the here seen chromosomal aberrations in adult primary AML seems to indicate for an adverse prognosis. (Source: BMC Hematology)
Source: BMC Hematology - August 31, 2018 Category: Hematology Source Type: research

Useful clinical features and hematological parameters for the diagnosis of dengue infection in patients with acute febrile illness: a retrospective study
ConclusionWe identified important clinical features and CBC parameters to differentiate dengue patients from other patients who had acute febrile illness from other causes. This identification could be done in local hospitals to give an accurate diagnosis, enabling further investigation to be tailored and treatment commenced earlier. (Source: BMC Hematology)
Source: BMC Hematology - August 29, 2018 Category: Hematology Source Type: research

Rapid access clinic for unexplained lymphadenopathy and suspected malignancy: prospective analysis of 1000 patients
ConclusionsIn conclusion, we demonstrate that Oncologist-led rapid access clinics are successful concepts to assess patients with unexplained lymphadenopathy. Our data suggest that a routine use of FNA should be reconsidered in this setting. (Source: BMC Hematology)
Source: BMC Hematology - August 14, 2018 Category: Hematology Source Type: research

Rare and unusual case of anti-factor XI antibodies in patient with plasma cell leukemia
ConclusionBoth PCL and anti-factor XI inhibitors are two very rare entities. To the best of our knowledge, this is the first reported case of a factor XI inhibitor arising in the setting of PCL. Factor inhibitors should be suspected in patients whose monoclonal gammopathies are accompanied by bleeding manifestations. (Source: BMC Hematology)
Source: BMC Hematology - August 10, 2018 Category: Hematology Source Type: research