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Immune modulator therapy compared with vitrectomy for management of complicated intermediate uveitis: a prospective, randomized clinical study
Conclusions: Pars plana vitrectomy and immune modulator therapy resulted in significant improvement in visual function in patients with persistent inflammation secondary to chronic intermediate uveitis. Despite this success, there remains a need for the determination of optimal indications for the use of each modality. Immune modulator therapy was successful for the treatment of diffuse macular edema associated with chronic intermediate uveitis, whereas pars plana vitrectomy was not.RESUMO Objetivo: Comparar os benef ícios e efeitos co laterais da vitrectomia via pars plana com os da terapia imunomo duladora sistêmica e...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Three versus five intravitreal aflibercept injections as the initial loading phase in the treatment of diabetic macular edema: one-year results
Conclusion: The 3+PRN and 5+PRN regimens showed similar 12-month visual and anatomical outcomes following treatment with intravitreal aflibercept injections in patients with macular edema.RESUMO Objetivo: Comparar a efic ácia de três injeções intravítreas mensais iniciais de aflibercept, seguidas de dosagem de pro re nata (3+PRN) versus cinco injeções mensais iniciais intravítreas de aflibercept, seguidas de doses de pro re nata (5 + PRN) em pacientes com edema macular diabético. Métodos: Foram analisados neste estudo retrospectivo e comparativo 60 pacientes que não receberam tratamento prévio com edema macu...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Ganglion cell layer thinning in diabetic patients without retinopathy: related or unrelated to total macular thickness?
Conclusions: Mean ganglion cell layer thickness was not lower in diabetic patients without retinopathy than in non-diabetic patients. Moreover, it exhibited a substantial correlation with total macular thickness. Parafoveal vessel density decreased before ganglion cell layer thinning was observed.RESUMO Objetivo: Pode ocorrer redu ção da espessura da camada de células ganglionares em pacientes diabéticos sem retinopatia. As relações desse achado pré-clínico com a espessura da retina ou a densidade reduzida de vasos parafoveais não foram estabelecidas. Este estudo investigou as relações da espessura da camada de...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Inner retinal thickness and optic disc measurements in obese children and adolescents
Conclusion: Compared to healthy children, obese children had greater binocular retinal nerve fiber layer thickness asymmetry and thinner retinal nerve fiber and ganglion cell-inner plexiform layers in several sectors. Blood lipid levels were not associated with retinal thickness or optic disc parameters in obese children.RESUMO Objetivo: O objetivo deste estudo foi avaliar os par âmetros da cabeça do nervo óptico e a espessura da camada interna da retina em crianças e adolescentes obesos. Métodos: Quarenta e um olhos de 41 participantes pediátricos obesos e 41 olhos de 41 controles saudáveis pareados por idade e s...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Aqueous humor heat-shock protein 70, periostin, and irisin levels in patients with pseudoexfoliation syndrome
Conclusions: Heat shock protein 70, periostin, and irisin levels increase in the aqueous humor of patients with pseudoexfoliation without glaucoma.RESUMO Objetivo: Comparar os n íveis de proteína de choque térmico 70, de periostina e de irisina no humor aquoso de pacientes com pseudoexfoliação com catarata sem glaucoma e compará-los com pacientes com catarata sem pseudoexfoliação. Métodos: Trinta e um olhos de 31 pacientes com pseudoexfoliação com catarata sem g laucoma e 30 olhos de 30 indivíduos com catarata foram incluídos neste estudo. Amostras de humor aquoso foram coletadas de todos os pacientes no mom...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Changes in the ganglion cell complex thickness after anti-VEGF treatment for diabetic macular edema
Conclusion: Our study showed that the ganglion cell complex thickness in patients with diabetic macular edema decreased after the anti-VEGF injections. We cannot ascertain whether the ganglion cell complex thickness decreases were due to effects of the anti-VEGF agents or to the natural disease course.RESUMO Objetivo: Avaliar as altera ções do complexo tomográfico das células ganglionares em pacientes com edema macular diabético tratados com injeções intravítreas do fator de crescimento endotelial anti-vascular (anti-VEGF). Métodos: Analisamos dados de 35 olhos de 35 pacientes previamente não tratados nos quais...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

A theoretical model for graft punch size calculations to prevent Descemet’s membrane folds following deep anterior lamellar keratoplasty
Conclusion: Adjustment of donor graft size based on the calculated arc diameter of the recipient bed reduced the development of Descemet ’ s membrane folds after deep anterior lamellar keratoplasty in steep corneas.RESUMO Objetivo: O comprimento da membrana de Descemet e o tamanho do enxerto doador na ceratoplastia lamelar anterior profunda n ão coincidem em córneas muito íngremes, o que pode levar às dobras da membrana de Descemet. O objetivo deste estudo é estabelecer um modelo teórico para cálculo do tamanho do enxerto para ceratoplastia lamelar anterior profunda e avaliar a sua eficácia na prevenção de dob...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Surgical results regarding the correction of macular hole with and without face-down posturing using 25% SF6 gas: a retrospective case series
Conclusion: Our results suggest that macular hole surgery with the use of short duration gas (SF6) is safe and effective and that maintaining a postural orientation of nonface-down posturing is also safe. However, these recommendations should be assessed further in a prospective and randomized study to comprehensively delineate the associated benefits and risks.RESUMO Objetivos: Comparar as taxas de sucesso anat ômico da vitrectomia e tamponamento de gás SF6 na cirurgia de buraco macular com e sem a postura pronada pós-operatória. Métodos: Foi realizado um estudo observacional, longitudinal e retrospectivo de série...
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

2020 and now: what has been accomplished in blindness prevention and what is next?
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - October 16, 2020 Category: Opthalmology Source Type: research

Biomechanics in DALK: Big bubble vs Manual lamellar dissection
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopia ou hipermetropia iso...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Missed opportunities on retinopathy of prematurity: the urgency of doing more
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopia ou hipermetropia iso...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

A warning against associating doxycycline with isotretinoin
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopia ou hipermetropia iso...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Bilateral Pseudomonas endophthalmitis after immediately sequential bilateral cataract surgery: primum non nocere
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopia ou hipermetropia iso...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Prescription for astigmatic ametropia revisited
ABSTRACT The approach to any refractive condition of the eye with regular astigmatism is more complicated than that for myopia or hyperopia alone. It requires familiarity with the complex images collectively identified as Sturm ’ s conoid. Fortunately, only three of those play a critical role in the interpretation of ametropia with astigmatism. This manuscript discusses a prescription strategy for ametropias associated with regular astigmatism evolved from those three key images.RESUMO A abordagem de qualquer condi ção refrativa do olho com astigmatismo regular é mais complicada do que a da miopia ou hipermetropia iso...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research

Morning glory disc anomaly associated with large facial infantile hemangioma as the presenting signs of PHACE syndrome
ABSTRACT Infantile hemangioma, the most common benign tumor in infancy, is usually an isolated condition occurring in many different locations in the body. However, large infantile hemangioma may be associated with other systemic malformations, including central nervous system, cerebrovascular, cardiac, and ophthalmology abnormalities, a condition termed PHACE syndrome. In this paper, we describe a case of PHACE syndrome that was presented with the unique association of a large facial infantile hemangioma and morning glory anomaly.RESUMO O hemangioma infantil é a causa mais comum de tumor benigno na infância e usualmente...
Source: Arquivos Brasileiros de Oftalmologia - July 30, 2020 Category: Opthalmology Source Type: research