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Validation of ROPScore to predict retinopathy of prematurity among very low birth weight preterm infants in a southern Brazilian population
Conclusions: The ROPScore was useful to identify preterm babies at risk for retinopathy of prematu rity. In this population, the ROPScore detected all patients at risk for any stage retinopathy of prematurity and severe retinopathy of prematurity. The ROPScore values in this study were similar to those previously described, thereby successfully validating the ROPScore for early detection of retin opathy of prematurity in very low birth weight preterm infants.RESUMO Objetivos: Avaliar a sensibilidade, especificidade e os valores de pontos de corte do ROPScore, um escore baseado em fatores de risco cumulativos capaz de prev...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

A three-dimensional printed photopolymer resin implant for orbital rehabilitation for evisceration
Conclusion: To the best of our knowledge, this is the first phase-1 clinical study to certify the biocompatibility of the Fullcure resin for orbital implants in humans. The 3D printing technology permits fast and accurate production of implants for this purpose.RESUMO Objetivos: Avaliar a biocompatibilidade das esferas produzidas por impressora tridimensional em eviscera ção. Pacientes e métodos: Evisceração por olho cego doloroso foi realizada em 10 pacientes consecutivos (8 mulheres, idade média: 46.8 ± 14.2 anos). Os implantes esféricos foram produzidos pelo sistema de prototipagem rápida utilizando dados tri...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Factors associated with vision-related quality of life in Brazilian patients with glaucoma
Conclusion: The standard automated perimetry mean deviation and the visual acuity of the better and worse eyes were associated with lower quality of life in Brazilian patients with glaucoma. Quality of life was mostly highly associated with the standard automated perimetry mean deviation of the worse eye.RESUMO Objetivo: Avaliar o impacto da acuidade visual, danos no campo visual e outros fatores na qualidade de vida em pacientes brasileiros com glaucoma. M étodos: Este foi um estudo transversal prospectivo incluindo 49 pacientes com glaucoma selecionados com base na presença de defeitos por perimetria automatizada p...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

In-the-bag toric intraocular lens implantation in the case of an anterior capsule tear: a case series
Conclusion: Placement of toric intraocular lens in the presence of an anterior capsule tear may be safe, at least in cases with a 30° angle between the anterior capsule tear and the intraocular lens haptic.RESUMO Objetivo: Analisar os resultados do implante de lentes intraoculares t óricas para rupturas capsulares anteriores durante a facoemulsificação. Métodos: A coorte desta série retrospectiva, consecutiva e intervencional de casos que inclui 8 pacientes. Um paciente foi excluído quando a lágrima foi usada para aumentar a rexe. O astigmatismo pré-operatório mé dio foi de -1,67 D (± 0,98) e a média da ...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Whole-exome sequencing in familial keratoconus: the challenges of a genetically complex disorder
Conclusion: Our findings show that a complete genotype-phenotype correlation could not be identified, suggesting that keratoconus is a genetically heterogeneous disease. In addition, we believe that whole-exome sequencing-based segregation analysis is probably not the best strategy for identifying variants in families with isolated keratoconus.RESUMO Objetivos: As causas gen éticas subjacentes do ceratocone são essencialmente desconhecidas. Aqui, realizamos o sequenciamento de todo exoma de duas famílias brasileiras com ceratocone. Métodos: O sequenciamento total do exoma foi realizado em 6 indivíduos com ceratocone...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Clinical implications of biopsy for posterior uveal melanoma
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Effects of antibiotics and antiseptics on conjunctival bacterial flora in patients undergoing intravitreal injections
ABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENTRAL) from inception to April 2018; references from included papers were also searched. The following keywords were used: lubricants OR artificial tears OR artificial tears, lubricants AND dry eye OR dry eye syndrome OR syndromes, dry eye OR dry eyes. Among the 2028 electronic search results, 29 full papers were retrieved and fou...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes: a systematic review
ABSTRACT This systematic review aimed to assess the effectiveness of using preservative-free artificial tears versus preserved lubricants for the treatment of dry eyes in Universidade Federal de Alagoas (PROSPERO 2018 CRD42018089933). Online databases were searched (LILACS, EMBASE, MEDLINE, and CENTRAL) from inception to April 2018; references from included papers were also searched. The following keywords were used: lubricants OR artificial tears OR artificial tears, lubricants AND dry eye OR dry eye syndrome OR syndromes, dry eye OR dry eyes. Among the 2028 electronic search results, 29 full papers were retrieved and fou...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Unilateral acute posterior multifocal placoid pigment epitheliopathy in a patient with a strongly positive purified protein derivative test
ABSTRACT A 27-year-old man presented with a complaint of decreased visual acuity in the right eye. Best-corrected visual acuity was 20/60 in the right eye and 20/20 in the left eye. Right eye fundoscopy revealed mild vitritis, multifocal yellowish lesions, and macular serous retinal detachment. Left eye evaluation was normal. Acute posterior multifocal placoid pigment epitheliopathy was diagnosed in the right eye. Complementary exams revealed a strong reaction to the Mycobacterium tuberculosis purified protein derivative test, thus treatment for tuberculosis was initiated. Baseline fluorescein angiography of the right eye ...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Extensive bulbar conjunctival Kaposi’s sarcoma as initial symptom of human immunodeficiency virus
ABSTRACT Here, we present a case in which extensive bulbar conjunctival Kaposi ’ s sarcoma was the initial presentation of human immunodeficiency virus in a 36-year-old man. The patient had a 3-month history of recurrent self-limited inferior conjunctiva hyperemia in the right eye, and presented with a painless bullous lesion in the right inferior bulbar conjunctiva persisting for 15 days. Surgical incision biopsy was performed at five locations and revealed a pattern compatible with Kaposi ’ s sarcoma. Serologic testing was positive for human immunodeficiency virus; however, the patient had no other symptoms, or knowl...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Phacoemulsification and 1% atropine eye drops for treatment of antimetropic congenital microcoria associated with cataracts
ABSTRACT A rare case of bilateral congenital microcoria associated with antimetropia in a 47-year-old man is here described. The patient presented with a chief complaint of progressive vision loss in his right eye over the past five years. A slit-lamp examination and ultrasound biomicroscopy confirmed congenital microcoria and cataracts. Phacoemulsification was performed using an iris expansion device and the anterior capsule was stained using the “ trypan down under ” technique. Preoperative considerations, the surgical approach, and postoperative management are discussed.RESUMO Um caso raro de microcoria cong ênita...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Bilateral metastases to the extraocular muscles from small cell lung carcinoma
We report a case of bilateral extraocular muscle metastases from a small cell lung carcinoma and provide a review of the relevant literature. A 56-year-old smoker presented with proptosis, motility changes, and a relative afferent pupillary defect of the left eye, with a previous history of a small cell lung carcinoma. An orbital computerized tomography scan revealed a mass restricted to the left medial rectus. An incisional biopsy confirmed metastasis. Visual acuity of the left eye decreased rapidly, and right globe proptosis became evident. Orbital magnetic resonance imaging at two months follow-up showed marked left orb...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Evaluation of three superior oblique surgical weakening procedures for A-pattern strabismus
Conclusion: All three superior oblique weakening procedures were effective for correcting A-pattern strabismus and fundus intorsion.RESUMO Objetivo: Avaliar tr ês procedimentos de debilitamento dos músculos oblíquos superiores para a correção de estrabismo com padrão em A: tenectomia, sutura em rédea (hang-back recession) e o uso de espaçadores de sutura oblíqua superior. Métodos: Os critérios de inclusão foram estrabismo padrão em A ≥ 10 Δ e desvio horizontal ≥ 10 Δ , sem outras anormalidades oculares e tempo de acompanhamento ≥ 6 meses. Os 24 pacientes (m édia de idade de 16,3 ± 8,1 anos; média...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Evaluation of fundus autofluorescence ımaging of diabetic patients without retinopathy
Conclusion: Fundus autofluorescence imaging analysis revealed that diabetic patients without retinopathy have significant fluorescence alterations. Therefore, a noninvasive imaging technique, such as fundus autofluorescence, may be valuable for evaluation of the retina of diabetic patients without retinopathy.RESUMO Objetivo: Avaliar a utilidade da autofluoresc ência do fundo de olho de pacientes diabéticos sem retinopatia para investigar lesões precoces na retina. Métodos: Imagens de autofluorescência do fundo de olho de pacientes com diabetes mellitus do tipo 2 sem retinopatia (grupo diabético) e indivíduos saud...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research

Expression of specificity protein 1 and collagen I in primary pterygial tissues
Conclusion: Specificity protein 1 and collagen I are expressed in normal conjunctival and pterygial tissues, but expression is significantly greater in the latter. Specificity protein 1 and collagen I may be involved in the regulation of the development of primary pterygium.RESUMO Objetivo: Determinar os perfis de express ão do fator de transcrição da proteína de especificidade 1 e do colágeno I em tecidos pterigiais primários e conjuntivais normais, e explorar o papel da proteína de especificidade 1 e colágeno I no desenvolvimento pterigial. Métodos: Foram coletados os tecidos pterigiais de 20 pacientes su bmet...
Source: Arquivos Brasileiros de Oftalmologia - September 9, 2019 Category: Opthalmology Source Type: research