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Reproducibility of retinal and choroidal measurements using swept-source optical coherence tomography in patients with Parkinson’s disease
Conclusions: Swept-source optical coherence tomography provides highly reproducible measurements of retinal and choroidal thickness in both the macular and peripapillary areas. The reproducibility is higher in measurements of retinal thickness versus choroidal thickness.RESUMO Objetivo: Avaliar a reprodutibilidade das medi ções da retina e da coroide nas áreas macular e peripapilar utilizando a tomografia de coerência ótica com fonte de varredura pacientes com doença de Parkinson. Métodos: Um total de 63 olhos de 63 pacientes com doença de Parkinson idiopática foram avaliados usando um protocolo 3D de tomogr afi...
Source: Arquivos Brasileiros de Oftalmologia - February 27, 2020 Category: Opthalmology Source Type: research

Impact of the type of anterior lamellar reconstruction on the success of modified Hughes procedure
Conclusion: Modified Hughes procedure is a safe and effective option for the reconstruction of small and large defects of the lower eyelid, regardless of the type of anterior lamella reconstruction (i.e., advancement flap or skin graft).RESUMO Objetivo: Determinar os resultados funcionais e cosm éticos a longo prazo de pacientes submetidos ao procedimento de Hughes modificado com diferentes tipos de reconstrução lamelar anterior para defeitos palpebrais inferiores. Métodos: Este estudo incluiu 58 pacientes que foram submetidos a um retalho de Hughes modificado para reconstrução das p álpebras inferiores após exci...
Source: Arquivos Brasileiros de Oftalmologia - February 27, 2020 Category: Opthalmology Source Type: research

Carnitine analysis in pterygium
Conclusion: That the carnitine levels in pterygium tissue were higher suggests that acceleration of cell metabolism developed secondary to chronic inflammation and the premalignant characteristics of pterygium tissue. High carnitine levels may also effectively suppress the apoptosis process. The data reported in our study indicate that further, more extensive studies of the carnitine profile could help clarify the pathogenesis of pterygium.RESUMO Objetivo: O objetivo deste estudo foi medir os n íveis de carnitina livre e acil-carnitina a nível metabolómico com espectrometria de massa em tandem no tecido do pterígio e ...
Source: Arquivos Brasileiros de Oftalmologia - February 27, 2020 Category: Opthalmology Source Type: research

Reliability of endoscopic dye transit test for prediction of functional success after diode laser and external dacryocystorhinostomy
Conclusion: The endoscopic dye transit test £60 s is a reliable tool to predict functional success and good prognosis after external or laser transcanalicular dacryocystorhinostomy.RESUMO Objetivo: Determinar a confiabilidade do teste endosc ópico do corante na predição do sucesso funcional após dacriocistorrinostomia. Métodos: Estudo transversal com 50 pacientes submetidos ao grupo de dacriocistorrinostomia externa ou grupo dacriocistorrinostomia transcanalicular e que possuíam dutos anatomicamente patentes pela irrigação, com seguimento mínimo de 6 meses. A dacriocistorrinostomia externa, definida como o tem...
Source: Arquivos Brasileiros de Oftalmologia - February 27, 2020 Category: Opthalmology Source Type: research

Public health strategy vs. golden standard for ocular cancer care in Brazil
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - February 27, 2020 Category: Opthalmology Source Type: research

Mechanisms and biomarker candidates in pterygium development
ABSTRACT Pterygium pathogenesis has been mainly asso ciated with UV light exposure; however, this association remains quite controversial. The complete mechanism of pterygium also remains to be clarified. Factors such as inflammation, viral infection, oxidative stress, DNA methylation, inflammatory mediators, extracellular matrix modulators, apoptotic and oncogenic proteins, loss of heterozygosity, microsatellite instability, lymphangiogenesis, epithelial-mesenchymal cell transition, and alterations in cholesterol metabolism have been identified as causes. Several studies aimed to clarify the molecular mechanisms underlyin...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Spontaneous outer retinal layer recovery in a case of hypertensive choroidopathy secondary to pre-eclampsia: a multimodal evaluation
ABSTRACT A 26-year-old woman presented at 28 weeks gestation with hypertensive choroidopathy associated with pre-eclampsia. Fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography (SD-OCT), fluorescein angiography, and indocyanine green angiography were performed in both eyes in the immediate postoperative period. SD-OCT images were obtained before delivery and during a 3-month follow-up. Fundus autofluorescence exhibited patchy hyper- and hypoautofluorescent lesions; fluorescein and indocyanine green angiography revealed areas of choroidal ischemia; and SD-OCT showed disorganization of th...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Ultrastructural changes detected using swept-source optical coherence tomography in severe vitreopapillary traction: a case report
In conclusion, swept-source optical coherence tomography aids in understanding the mechanism underlying visual loss in vitreopapillary traction. Moreover, posterior vitrectomy can effectively promote anatomical and visual improvements in these cases.RESUMO A tra ção vitreopapilar é uma condição incomum caracterizada por forte adesão e tração da hialoide posterior no disco óptico e retina peripapilar, levando à elevação do disco óptico e à perda visual. Um homem de 85 anos apresentou uma história de 6 meses de perda visual lenta e progressiva no olho esquerdo, juntamente com edema do disco óptico. A tomograf...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Primary multifocal anaplastic large cell lymphoma with eyelid involvement: a case report
We report the case of a 73-year-old woman with a relapsing primary cutaneous anaplastic large cell lymphoma on her eyelid. A systemic extension study excluded extracutaneous involvement. Systemic chemotherapy resulted in an optimal response, with complete regression of the cutaneous lesions. There has been no recurrence during the 2 years of follow-up.RESUMO O acometimento ocular adicional nos dist úrbios linfoproliferativos CD30+ é raro. Relatamos o caso de uma mulher de 73 anos com linfoma de grandes células anaplásicas primárias recidivantes em sua pálpebra. A avaliação sistêmica excluiu envolvimento extracutâ...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Visual loss following cosmetic facial filler injection
ABSTRACT Facial filler injection for soft-tissue augmentation, wrinkle reduction, and rejuvenation has recently become increasingly popular. This procedure is well accepted and widely performed because of its safety and excellent outcomes. However, complications may occur even in the most skilled hands. A 36-year-old female presented with immediate loss of vision in her right eye following the periocular injection of cosmetic hyaluronic acid facial filler into the glabellar region. The visual loss was accompanied by weakness of her left arm. Blindness may complicate cosmetic facial filler injection. The treating physician ...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Anterior chamber characteristics assessed by rotating Scheimpflug imaging in patients with retinitis pigmentosa
Conclusions: The results of the present study demonstrated that patients with retinitis pigmentosa have different anterior segment parameters and corneal aberrations compared to healthy controls. These results should be supported by further studies.RESUMO Objetivo: Este estudo visou avaliar par âmetros do segmento anterior e aberrações corneanas em pacientes com retinite pigmentosa através de imagens de Scheimpflug e comparar os achados com os de controles saudáveis. Métodos: Este foi um estudo caso-controle unicêntrico que incluiu pacientes com o diagnóstico de retinite pigmentos a em acompanhamento no Departame...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

The association between genetic polymorphism of glutathione peroxidase 1 (rs1050450) and keratoconus in a Turkish population
Conclusions: This study evaluated possible relationships between rs1050450, rs1001179, and rs4880 polymorphisms and keratoconus susceptibility. We found a possible association between glutathione peroxidase 1 rs1050450 polymorphism and an increased risk of keratoconus. However, the genotype and allele frequencies were identical in the catalase rs1001179 and superoxide dismutase 2 rs4880 polymorphisms. Further studies are needed to analyze the effect of such variations in identifying keratoconus susceptibility.RESUMO Objetivo: Investigar as poss íveis associações entre o ceratocone e os polimorfismos rs1001179 da cata...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Prevalence of cataract complications in patients with pseudoexfoliation syndrome in Northwestern Spain
Conclusion: Zonular dialysis and intraoperative miosis were intraoperative complications in cataract surgery patients with pseudoexfoliation syndrome when compared to controls.RESUMO Objetivo: Avaliar a rela ção entre a síndrome de pseudoexfoliação e a prevalência de complicações e fatores clínicos relacionados em pacientes submetidos à cirurgia de catarata. Métodos: Foi realizado um estudo retrospectivo de coorte de 503 de 551 pacientes que se submeteram à cirurgia de facoemulsificação d urante 2 anos em um distrito de saúde no noroeste da Espanha. No total, 120 dos 681 olhos submetidos ao procedimento ap...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

Refractive and visual outcomes after Ferrara corneal ring segment implantation at a 60% depth in keratoconic eyes: case series
Conclusions: Ferrara intrastromal corneal ring segment insertions at a depth of 60% yield satisfactory visual, refractive, and keratometric results in keratoconic eyes.RESUMO Objetivos: Este estudo aborda os resultados refrativos, topogr áficos, acuidade visual e tomografia de coerência óptica, 12 meses após a inserção do segmento de Anel de Ferrara em túnel corneano a 60% de profundidade com o laser de femtosegundo, em pacientes com ceratocone. Métodos: Série de casos não comparativos, prospectivos e intervencionistas. R ealizamos a inserção do Anel de Ferrara através de incisão com o laser de femtosegundo...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research

New perspectives on macular hole surgery at three years of follow-up
Conclusion: Combined surgery including vitreous base removal and internal limiting membrane peeling after staining with Brilliant Blue G (0.5 mg/mL) for the management of idiopathic macular holes resulted in adequate staining, best-corrected visual acuity improvement, and macular hole closure with no signs of ocular toxicity at the three-year follow-up examination.RESUMO Objetivo: Determinar, ap ós 3 anos de seguimento, as taxas de sucesso funcional e anatômico e a segurança da cirurgia combinada sem sutura, incluindo remoção da base vítrea e da membrana limitante interna após coloração com azul brilhante (0,5 m...
Source: Arquivos Brasileiros de Oftalmologia - October 24, 2019 Category: Opthalmology Source Type: research