Arquivos Brasileiros de Oftalmologia Arquivos Brasileiros de Oftalmologia RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Using Big Data in eye research to answer important scientific questions
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - May 16, 2019 Category: Opthalmology Source Type: research

An eye on hepatitis C: a review
ABSTRACT This review aims to caution ophthalmologists about the ocular consequences leading to the diagnosis of hepatitis C virus infection. In addition, in this context, the effects of old and new drugs are discussed in the ophthalmological setting. The importance of early diagnosis and the curative treatment of the disease has been reported in the national and international literature, demonstrating that its progression has important implications for daily clinical and surgical ophthalmological practice. Despite the scarcity of studies on new direct-acting antiviral drugs, fewer side effects of these drugs have been show...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Retinal dystrophies and variants in PRPH2
This report presents three patients diagnosed with macular dystrophies with variants in PRPH2. Peripherin-2, the protein of this gene, is important in the morphogenesis and stabilization of the photoreceptor outer segment. Peripherin-2 deficiencies cause cellular apoptosis. Moreover, pathogenic variants in PRPH2 are associated with various diseases, such as pattern, butterfly-shaped pattern, central areolar, adult-onset vitelliform macular, and cone-rod dystrophies as well as retinitis pigmentosa, retinitis punctata albescens, Leber congenital amaurosis, fundus flavimaculatus, and Stargardt disease.RESUMO | Este relato apr...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?
ABSTRACT | Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Fluorescein angiography indicated anteri...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole
We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Laboratory tests revealed Paecilomyces lilacinus as the infectious agent. The patient was then maintained with oral voriconazole and eye drops for three months, after which the...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

A case of late-onset capsular block syndrome and its surgical treatment
ABSTRACT | Capsular block syndrome is a rare complication of phacoemulsification surgery with continuous curvilinear capsulorhexis and intraocular lens implantation. Here, we report a case of very late-onset capsular block syndrome that developed 13 years after cataract extraction and present the surgical approach used for its successful treatment.RESUMO | S índrome do bloqueio capsular é uma complicação incomum da cirurgia de facoemulsificação com capsulorrexis curvilínea contínua e implante de lente intraocular. Nós relatamos um caso de síndrome de bloqueio capsular de início tardio que se desenvolveu após 13...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Evaluation of nutritional status in children with amblyopia
Conclusion: Amblyopic children are significantly deficient in some inorganic elements. Inorganic elements, vitamin B12, and folate may play an important role in the visual development of amblyopic children.RESUMO Objetivo: Nosso objetivo foi comparar o índice de massa corporal e o nível de vitaminas e minerais de crianças com e sem ambliopia. Métodos: Crianças amblióticas com idades entre 5 e 18 anos (n=46) e crianças controle pareadas por idade (n=32) foram avaliadas quanto a parâmetros antropométricos, incluindo altura, peso, índice d e massa corporal e características demográficas. A vitamina B12 e o folat...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Correlation of the aqueous humor total antioxidant capacity, total oxidant status, and levels of IL-6 and VEGF with diabetic retinopathy status
This study analyzed 86 pairs of eyes of 86 patients. All groups were statistically simi lar in age and sex, but the total antioxidant capacity was lowest in patients with proliferative diabetic retinopathy. Moreover, the total oxidant status and levels of vascular endothelial growth factor and interleukin-6 were found to slightly increase according to the retinopathy status. Conclusio n: Oxidative stress, interleukin-6, and vascular endothelial growth factor in the aqueous humor seem to play important roles in the pathogenesis of diabetic retinopathy, especially in the proliferative type.RESUMO Objetivo: Procurou-se comp...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Effect of contact lenses on ocular biometric measurements based on swept-source optical coherence tomography
Conclusions: Sept-source optical coherence tomography based lens thickness measurements while wearing soft contact lenses are comparable to those of the naked eye. However, the thickness and the optical design of the soft contact lens may lead to significant differences in the axial lengh, central corneal thickness, anterior chamber deph, and keratometric measurements.RESUMO Objetivo: Determinar a confiabilidade da tomografia de coer ência óptica de varredura em casos especiais em que lentes de contato gelatinosas não podem ser removidas ao realizar medições biométricas. Métodos: Oito indivíduos foram incluídos ...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Comparison of choroidal thickness in patients with active and stable thyroid eye disease
Conclusions: Subfoveal choroidal thickness was significantly higher in patients with thyroid eye disease in the active phase than in those with stable phase disease.RESUMO Objetivo: Comparar a espessura da coroide nas fases ativa e est ável da doença ocular tireoidiana. Métodos: Quarenta e sete olhos, de 47 pacientes com doença ocular tireoidiana foram estudados prospectivamente. Os pacientes foram avaliados com base em seus escores de atividade clínica, com escore de 33 definidos como doença ativa. As medidas subfoveais, m aculares temporais, maculares nasais, peripapilares temporais e da espessura da coroide peri...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Long-term use of topical tacrolimus ointment: a safe and effective option for the treatment of vernal keratoconjunctivitis
ABSTRACT Purpose: To assess the compliance, efficacy, and safety of the long-term use of topical tacrolimus for the clinical management of vernal keratoconjunctivitis. Methods: The medical records of patients with vernal keratoconjunctivitis undergoing long-term treatment with 0.03% topical tacrolimus were retrospectively reviewed. The duration of tacrolimus use and the causes for drug discontinuation were used to assess treatment compliance. To assess drug efficacy, the need for and the number of times that topical corticosteroids were used to control symptoms were registered. Side effects related to tacrolimus use were...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Efficacy of preoperative nonsteroidal anti-inflammatory drug and the re-dilation technique in minimizing miosis after femtosecond laser in cataract surgery
Conclusion: Preoperative administration of nonsteroidal anti-inflammatory drug and the re-dilation technique resulted in no significant pupil size variation in eyes that were pretreated with the femtosecond laser, when comparing the measurements made before the laser application and at the beginning of phacoemulsification. This approach can avoid the need to proceed with cataract extraction with a constricted pupil.RESUMO Objetivo: Avaliar a efic ácia do uso de anti-inflamatório não-esteróide no pré-operatório e aplicação da técnica de re-dilatação quando necessária para minimizar a variação do tamanho pupil...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

The Amazon Ocular Oncology Center: The first three years
ABSTRACT Purpose: To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil. Methods: Here, we report patient information including patients ’ age, gender, diagnosis, treatment, and city of origin. Results: Two hundred and twenty-one patients were included on this study: 160 (72%) patients came from the city of Manaus, 52 (24%) from other cities in Amazonas, and 9 (4%) from other states. Of the 221 patients, 150 (68%) were afflicted with benign lesions and the remaining 71 (32%) had malignant lesions. Benign diagnosis included pterygium, chalazium, c...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis
Conclusion: This study suggests a beneficial effect of accelerated collagen cross-linking in cases of Acanthamoeba keratitis with corneal melting. Thus, collagen cross-linking may be considered as adjuvant treatment for Acanthamoeba keratitis.RESUMO Objetivo: Relatar nossa experi ência inicial no tra tamento da ceratite por Acanthamoeba com reticulação acelerada de colágeno corneano. Métodos: Revisão retrospectiva de prontuários de pacientes diagnosticados com ceratite por Acanthamoeba, com deformação progressiva da córnea, tratados com reticulação acelerada de colágeno. Resultados: Seis olhos (5 pacientes)...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research

Intermittent exotropia evaluation using the propedeutics proposed by Kushner: a 25-year study
Conclusion: The results show the importance of complete propedeutics, since there is a higher rate of late undercorrection in cases with outdoor sensitivity and increased deviation after occlusion.RESUMO Objetivo: Avaliar os impactos cl ínico e cirúrgico dos fenômenos que podem ocorrer na exotropia intermitente. Métodos: Os prontuários de casos de exotropia intermitente de 1991 a 2014 foram revisados retrospectivamente. Todos os pacientes foram submetidos a uma serie de medidas incluindo o protocolo com oclusão monocular com base na propedêutica proposta por Kushner. Resultados: Outdoor sensitivity foi observada...
Source: Arquivos Brasileiros de Oftalmologia - February 5, 2019 Category: Opthalmology Source Type: research