Investigating the effect of intracameral cefuroxime on oxidative stress and apoptosis in the rat cornea
CONCLUSION: Immunohistochemical examination revealed that intracameral cefuroxime increased apoptosis when compared to the sham and balanced salt solution groups. Moreover, intracameral cefuroxime increased oxidative stress in the cornea and simultaneously induced apoptosis.RESUMO OBJETIVO: Examinamos o efeito da administra ção intracameral da cefuroxima sobre o estresse oxidativo e a apoptose endotelial no tecido corneano de ratos. MÉTODOS: No total, 30 ratos foram divididos em 3 grupos de 10 ratos cada (administração intracameral de cefuroxima 0,1 mg/0,01 mL (grupo cefuroxima), administração intracameral de s ol...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Ultrasonographic characteristics of active ocular toxoplasmosis
Conclusion: Ultrasonography is helpful for detecting important intraocular findings of acute ocular toxoplasmosis that can be hindered by medial opacity or posterior synechiae.RESUMO Objetivo: Avaliar os achados da ultrassonografia na toxoplasmose ocular ativa. M étodos: Quarenta e sete olhos com toxoplasmose ocular ativa em 47 pacientes foram submetidos à ultrassonografia ocular pela técnica transpalpebral (transdutor de 10 MHz) e fundo de olho. Os prontuários médicos foram revistos retrospectivamente. Resultados: A ultrassonografia ocular revelou vit reíte, descolamento vítreo posterior, espessamento da parede ...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Effects of benzalkonium chloride and cyclosporine applied topically to rabbit conjunctiva: a histomorphometric study
Conclusion: This study demonstrated the magnitude of conjunctival injury caused by chronic instillation of benzalkonium chloride. Although cyclosporine did not mitigate the effects on goblet cells, its addition minimized inflammatory angiogenesis induced by benzalkonium chloride.RESUMO Objetivo: A instila ção crônica de cloreto de benzal­cônio, um conservante, tem efeitos inflamatórios na superfície ocular. No entanto, a adição do agente anti-inflamatório ciclosporina a um protocolo terapêutico pode atenuar esses efeitos. Este estudo comparou os efeitos tóxicos de uma solução de cloreto de benzalcônio a 0,...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Optic nerve involvement in ocular toxoplasmosis: 12 year data from a tertiary referral center in Turkey
Conclusions: Optic nerve involvement was common in patients with ocular toxoplasmosis. The main type of optic nerve involvement was caused by activation of an old juxtapapillary lesion. Treatment was quickly effective, but the best-corrected visual acuity was dependent on the presence of a scar in the papillomacular bundle.RESUMO Objetivos: Avaliar a preval ência, características clínicas e tipos de acometimento do nervo óptico em pacientes com toxoplasmose ocular. Métodos: Para este estudo retrospectivo transversal, examinamos todos os pacientes com toxoplasmose ocular ativa encaminhados ao nosso Setor de Uveíte n...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

The effect of panretinal photocoagulation on confocal laser scanning ophthalmoscopy and stereo photographic parameters of optic disk topography in patients with diabetic retinopathy
Conclusion: Our results suggest that panretinal photocoagulation does not cause morphological optic disk changes in patients with diabetic proliferative retinopathy after 1 year of follow-up.RESUMO Objetivo: Determinar o efeito da panfotocoagula ção retiniana nos parâmetros topográficos do disco óptico em pacientes não glaucomatosos com retinopatia diabética proliferativa. Métodos: Este é um estudo observacional pros­pectivo e unicêntrico. Trinta e oito olhos de 26 pacientes dia­béticos foram submetidos à panfotocoagulação retiniana para retinopatia diabética proliferativa. As estereofotografias e os par...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Complications in the first 10 phacoemulsification cataract surgeries with and without prior simulator training
Conclusions: The training with the Eyesi® cataract surgery sim ulator significantly reduced the total number of intraoperative complications in the first 10 phacoemulsification cataract surgeries performed by ophthalmology residents.RESUMO Objetivo: Avaliar se o treinamento de residentes m édicos com o simulador de cirurgia de catarata Eyesi® reduz a ocorrência de complicações intraoperatórias. Métodos: Estudo retrospectivo em que foram avaliadas as primeiras 10 cirurgias de facoemulsificação realizadas por dois grupos de residentes de Oftalmologia do segundo ano, no períod o de 2014 a 2015. O primeiro Grupo f...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Ocular surface evaluation in pediatric Hashimoto's thyroiditis without thyroid-associated ophthalmopathy
Conclusions: The study demonstrates several ocular surface changes in children with Hashimoto's thyroiditis. These findings may indicate a tendency for dry eye in pediatric Hashimoto's thyroiditis patien ts without clinical evidence of thyroid-associated ophthalmopathy.RESUMO Objetivo: Avaliar as caracter ísticas da superfície ocular em crianças com tireoidite de Hashimoto sem oftalmopatia associada à tireoide e comparar os resultados com aqueles de crianças saudáveis. Métodos: Vinte e duas crianças com tireoidite de Hashimoto (Grupo 1) e 20 crianças saudáveis sem qualquer distúrbio ocula r e/ou sistêmico (Gr...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Intravitreal neurodegenerative and inflammatory mediators in proliferative diabetic retinopathy
Conclusions: Cellular mediators involved in neurodegeneration and inflammation demonstrated increased levels in the vitreous humor of patients with proliferative diabetic retinopathy and may be part of the pathogenesis of diabetic retinopathy.RESUMO Objetivo: Comparar as concentra ções intravítreas de mediadores celulares envolvidos na neurodegeneração, inflamação e angiogênese em pacientes com retinopatia diabética proliferativa e outras doenças vítreo-retinianas. Métodos: Um ensaio imunomagnético foi utilizado para medir os níveis vítreos do fator derivado d o epitélio pigmentar, amilóide P sérico, pr...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Evaluation of corneal layers and anterior sclera in patients with primary Sjögren's syndrome
Conclusions: Pre-ocular tear film, as measured by anterior segment optical coherence tomography, was thinner in patients with primary Sj ögren's syndrome than in the healthy controls. The thicknesses of corneal layers and anterior sclera were similar between the groups.RESUMO Prop ósito: Nosso objetivo foi comparar a espessura da esclera anterior, camadas da córnea e do filme lacrimal pré-ocular entre pacientes com síndrome de Sjögren primária e indivíduos saudáveis. Métodos: Cinquenta e um pacientes com síndrome de Sjögren primária e 41 controles saudáveis fora m recrutados neste estudo comparativo e trans...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Relationship between erythrocyte sedimentation rate and choroidal and retinal thickness in Behçet's disease
ABSTRACT Purpose: To compare retinal and choroidal thickness in patients with Beh çet's disease with and without ocular involvement as well as to evaluate the correlation between erythrocyte sedimentation rate and choroidal thickness among patients with Behçet's disease. Methods: This was a prospective interventional study investigating erythrocyte sedimentation as well as cho roidal and retinal thickness among patients with Behçet's disease. Patients who were diagnosed based on The International Criteria for Behçet's Disease with (Group A) or without (Group B) ocular involvement and a matched control group (Group C)...
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Medical acumen and scientific approach meet the FINER method
(Source: Arquivos Brasileiros de Oftalmologia)
Source: Arquivos Brasileiros de Oftalmologia - August 19, 2019 Category: Opthalmology Source Type: research

Myriad applications of dental pulp stem cells
ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. In this review, we summarize recent work from clinical studies investigating how glaucoma can affect driving performance. Patients with glaucoma are more likely to be involved in motor vehicle collisions when compared to h...
Source: Arquivos Brasileiros de Oftalmologia - May 16, 2019 Category: Opthalmology Source Type: research

Effects of accelerated corneal crosslinking on the topographic parameters of patients with progressive keratoconus
ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. In this review, we summarize recent work from clinical studies investigating how glaucoma can affect driving performance. Patients with glaucoma are more likely to be involved in motor vehicle collisions when compared to h...
Source: Arquivos Brasileiros de Oftalmologia - May 16, 2019 Category: Opthalmology Source Type: research

Long-term outcomes with Boston type I keratoprosthesis in ocular burns
ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. In this review, we summarize recent work from clinical studies investigating how glaucoma can affect driving performance. Patients with glaucoma are more likely to be involved in motor vehicle collisions when compared to h...
Source: Arquivos Brasileiros de Oftalmologia - May 16, 2019 Category: Opthalmology Source Type: research

Retinal venous occlusive disease requiring multifunctional drug therapy
ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. In this review, we summarize recent work from clinical studies investigating how glaucoma can affect driving performance. Patients with glaucoma are more likely to be involved in motor vehicle collisions when compared to h...
Source: Arquivos Brasileiros de Oftalmologia - May 16, 2019 Category: Opthalmology Source Type: research