Biological evaluation of rare earth complexes bearing 1H ‐imidazo[4,5‐f]‐1,10‐phenanthroline moiety as promising anticancer chemotherapeutics
Six lanthanide(III) complexes with the 2 ‐(naphthalen‐1‐yl)‐1H‐imidazo[4,5‐f]‐1,10‐phenanthroline ligand have been synthesized and characterized. Low IC50 values of these complexes were measured with three human cancer cell lines. Complex5 could induce BEL ‐7404 cancer cell apoptosis via the extrinsic pathway with high expression of caspase‐8, resulting in caspase‐3 activation. Furthermore, complex5 could significantly suppress BEL ‐7404 cell proliferation via induced apoptosis with G2/M phase cell cycle. Six lanthanide(III) complexes with the 2 ‐(naphthalen‐1‐yl)‐1H‐imidazo[4,5‐f]‐1,1...
Source: Applied Organometallic Chemistry - October 24, 2018 Category: Chemistry Authors: Yue Liu,
Xue ‐Quan Zhou,
Jing Lu,
Si‐Tong Li,
Yan Nie,
Jin‐Lei Tian,
Xin Liu,
Shi‐Ping Yan Tags: FULL PAPER Source Type: research
Facile fabrication of BUC ‐21/g‐C3N4 composites and their enhanced photocatalytic Cr(VI) reduction performances under simulated sunlight
A series of enhanced photocatalytically active BUC ‐21/g‐C3N4 composites have been prepared via ball ‐milling. The optimal B100G100 exhibited excellent photocatalytic activities for Cr(VI) reduction under the simulated sunlight and real sunlight irradiation, which is obviously superior to pure BUC‐21 and g‐C3N4. Also, the corresponding mechanism was proposed and clarified. A series of BUC ‐21/g‐C3N4 composites were facilely fabricated from two ‐dimensional metal–organic framework BUC‐21 and two‐dimensional metal‐free polymer semiconductor graphitic carbon nitride (g‐C3N4) through ball ‐milling, ...
Source: Applied Organometallic Chemistry - October 24, 2018 Category: Chemistry Authors: Xiao ‐Hong Yi,
Fu‐Xue Wang,
Xue‐Dong Du,
Peng Wang,
Chong‐Chen Wang Tags: FULL PAPER Source Type: research
Biological evaluation of rare earth complexes bearing 1H ‐imidazo[4,5‐f]‐1,10‐phenanthroline moiety as promising anticancer chemotherapeutics
Applied Organometallic Chemistry, EarlyView. (Source: Applied Organometallic Chemistry)
Source: Applied Organometallic Chemistry - October 24, 2018 Category: Chemistry Authors: Yue Liu,
Xue ‐Quan Zhou,
Jing Lu,
Si‐Tong Li,
Yan Nie,
Jin‐Lei Tian,
Xin Liu,
Shi‐Ping Yan Source Type: research
Desulfinative and denitrogenative palladium ‐catalyzed cross‐coupling of arylsulfonyl hydrazides with aryl diazonium salts
Arylsulfonyl hydrazides and aryl diazonium salts can be used as coupling participants in PdCl2/Dcypm ‐catalyzed cross‐coupling reactions. Various substrates were smoothly converted to form corresponding biaryl products in good to excellent yields. Advantages of this reaction include good functional group tolerance, high reactivity, relatively mild conditions and easy access to the coupling part ners. Terphenyls were effectively transformed in the reaction, and the reaction could be scalable with good efficiency. Palladium ‐catalyzed cross‐coupling of arylsulfonyl hydrazides with aryl diazonium salts to provide biar...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Yonghui Shang Tags: COMMUNICATION Source Type: research
Issue Information
No abstract is available for this article. (Source: Applied Organometallic Chemistry)
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Tags: ISSUE INFORMATION Source Type: research
Cover Image
The cover image is based on the Full PaperEffects of addition mode on Zn –Co double metal cyanide catalyst for synthesis of oligo(propylene‐carbonate) diols by Na An et al.,https://doi.org/10.1002/aoc.4509. (Source: Applied Organometallic Chemistry)
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Na An,
Qifeng Li,
Ning Yin,
Maoqing Kang,
Junwei Wang Tags: COVER IMAGE Source Type: research
Co(III), V(IV) and Cu(II) complexes of bidentate N,O ‐donor Schiff base ligands: Characterization, anticancer activities and metal oxide nanoparticles preparation via solid state thermal decomposition
Three new Schiff base complexes were synthesized and fully characterized. The complexes were used as solid precursor to produce pure ‐phase nanoparticles by solid state thermal decomposition. In vitro anticancer activity of compounds was evaluated against the MKN‐45 cancer cells. Results showed promising anticancer activities of prepared complexes. Three new mononuclear Schiff base complexes [Co(L1)3 (1), VO(L1)2 (2) and Cu(L2)2 (3)] were synthesized, characterized and used as a precursor for preparation of metal oxide nanoparticles. The crystal structure of compounds was determined using single crystal X ‐ray diffra...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Zeinab Abbasi,
Mehdi Salehi,
Ali Khaleghian,
Maciej Kubicki Tags: FULL PAPER Source Type: research
MIL ‐101(Fe) hexagonal microspindle as a highly efficient, reusable and versatile catalyst for benzo‐fused heterocyclic nucleus synthesis
MIL ‐101(Fe) hexagonal microspindle was prepared in one step and used as a novel heterogeneous catalyst for benzo‐fused heterocyclic nucleus synthesis. The heterogeneous catalyst was characterized. High efficiency, mild reaction conditions, easy work‐up and use of MOF‐based catalyst are importan t benefits of this methodology. A highly reusable, efficient and versatile MIL ‐101(Fe) catalyst was prepared and characterized using various techniques including Fourier transform infrared spectroscopy, X‐ray diffraction, field emission scanning electron microscopy and energy‐dispersive X‐ray spectroscopy. This het...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Ramin Karimian,
Seyed Javad Davarpanah Tags: FULL PAPER Source Type: research
A series of new lanthanide complexes with 2 ‐bromo‐5‐methoxybenzoic acid and 5,5′‐dimethyl‐2,2′‐bipyridine: Crystal structures, thermal behavior, luminescent and magnetic properties
Complexes1–3 are isostructural and each metal center is nine ‐coordinated, while complex4 is eight ‐coordinated exhibiting a different structure. All binuclear units are assembled into 1D, 2D and 3D supramolecular structures via π–π stacking and hydrogen bonding interactions. The luminescent properties were studied, and the lifetime of complex2 is 0.693 ms. Four new binuclear lanthanide complexes [Ln(2 ‐Br‐5‐MOBA)3(5,5 ′‐DM‐2,2′‐bipy)]2 (Ln = Gd(1), Tb(2), Dy(3), Er(4); 2 ‐Br‐5‐MOBA = 2‐bromo‐5‐methoxybenzoate; 5,5′‐DM‐2,2′‐bipy = 5,5′‐dimethyl‐2,2′‐bipyridin...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Wu Xiao ‐Hui,
Ren Ning,
Zhang Jian‐Jun Tags: FULL PAPER Source Type: research
Synthesis, characterization and in vitro anticancer, DNA binding and cleavage studies of Mn (II), Co (II), Ni (II) and Cu (II) complexes of Schiff base ligand 3 ‐(2‐(1‐(1H‐benzimidazol‐2‐yl)ethylidene)hydrazinyl)quinoxalin‐2(1H)‐one and crystal structure of the ligand
Schiff base ligand 3 ‐(2‐(1‐(1H‐benzimidazol‐2‐yl)ethylidene)hydrazinyl)quinoxalin‐2(1H) ‐one and its Mn (II), Co (II), Ni (II) and Cu (II) complexes were synthesized and characterized. DNA binding studies were conducted, DNA cleavage using pBR322 DNA was studied andin vitro anticancer activities were investigated using HeLa, B16 ‐F10, SKOV3 and MCF7 cell lines. A Schiff base ligand, 3 ‐(2‐(1‐(1H‐benzimidazol‐2‐yl)ethylidene)hydrazinyl)quinoxalin‐2(1H) ‐one (BZHQO), has been synthesized by the condensation of 3‐hydrazinylquinoxalin‐2(1H) ‐one and 1‐(1H‐benzoimidazol‐2‐yl) eth...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Panaganti Sukanya,
Chittireddy Venkata Ramana Reddy Tags: FULL PAPER Source Type: research
Synthesis, characterization and biological applications of some substituted pyrazoline based palladium (II) compounds
Synthesis and characterization of pyrazoline ‐based Pd (II) complexes have been carried out as an alternative to platinum‐based drugs. The complexes have been evaluated for diverse biological activities like DNA binding, nucleolytic, antibacterial and antituberculosis activities and cytotoxicity with appropriate methods along with kinetic and thermodynamic parameters. Palladium (II) complexes of the type [PdLCl2] (where L = substituted pyrazoline ligands) have been synthesized. The metal complexes (5a‐5f) have been characterized by various spectroscopic and analytical techniques like1H ‐NMR,13C ‐NMR, LC–MS, ...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Khyati P. Thakor,
Miral V. Lunagariya,
Bhupesh S. Bhatt,
Mohan N. Patel Tags: FULL PAPER Source Type: research
Ferrocene ‐appended donor–π–acceptor Schiff base: Structural, nonlinear optical, aggregation‐induced emission and density functional theory studies
New donor –π‐acceptor ferrocenyl Schiff bases were synthesized and their nonlinear optical properties investigated. Frontier molecular orbital (HOMO–LUMO) energies were calculated. Aggregation‐induced emission studies revealed that the Schiff bases show strong dark yellow fluorescence emissions. New ferrocenyl Schiff bases [Fc ─C(H)═N─C6H3(OH)(R)] (R = H (1), NO2 (2)) have been synthesized and characterized using various techniques. Compound2 was further confirmed using single ‐crystal X‐ray diffraction analysis. Solvatochromism studies of2 showed redshift from nonpolar to polar solvents. In addition,...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Ezhumalai David,
Krishnan Thirumoorthy,
Nallasamy Palanisami Tags: FULL PAPER Source Type: research
Preparation and characterization of magnetically separable MgFe2O4/Mg(OH)2 nanocomposite as an efficient heterogeneous catalyst for regioselective one ‐pot synthesis of β‐chloroacetates from epoxides
Magnetically separable MgFe2O4/Mg(OH)2 nanoparticles were fabricated and characterized. These nanoparticles were used as a catalyst for regioselective one ‐pot synthesis of β‐chloroacetates from epoxides in EtOH at room temperature giving high to excellent yields. The nanocatalyst was easily separated and reused several times without any significant loss of efficiency or magnetic property. Magnetically separable MgFe2O4/Mg(OH)2 nanoparticles were fabricated and characterized using various techniques. These nanoparticles were used as a new catalyst for regioselective one ‐pot synthesis of β‐chloroacetates from epo...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Shadi Hassanzadeh,
Ronak Eisavi,
Mojtaba Abbasian Tags: FULL PAPER Source Type: research
Effects of addition mode on Zn –Co double metal cyanide catalyst for synthesis of oligo(propylene‐carbonate) diols
Effects of dropping mode on Zn –Co double metal cyanide (DMC) catalyst are investigated using three different dropping methods. The factors that affect crystalline state are summarized and a flower‐like morphology is observed which endows the DMC catalyst with a large surface area. In copolymerization reaction, appropriate O/ Zn value is beneficial to suppress the formation of by‐product. And a catalyst with excellent catalytic performance is prepared by an improved parallel‐flow dropping method. Zn –Co double metal cyanide (DMC) complexes are promising catalytic systems for copolymerization of epoxide and CO2. I...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Na An,
Qifeng Li,
Ning Yin,
Maoqing Kang,
Junwei Wang Tags: FULL PAPER Source Type: research
Experimental and computational studies of novel ferrocene –pyranylidene dyads: Synthesis, characterization and electrochemical and linear optical properties
Ferrocene based D ‐π‐A analogs were synthesized aiming to use them in optical applications.
Electrochemical, and photochemical properties of these compounds were studied.
Quantum chemistry study was performed on synthesized compounds with the DFT approach. A series of mono ‐condensed ferrocene–pyranylidene dyads in the form of donor–spacer–acceptor hybrid have been synthesized and characterized using1H NMR,13C NMR, Fourier transform infrared and mass spectroscopies and CHN analysis. The electrochemical and photochemical properties of these compounds were studied using UV –visible spectroscopy and cyclic volt...
Source: Applied Organometallic Chemistry - October 23, 2018 Category: Chemistry Authors: Reza Teimuri ‐Mofrad,
Keshvar Rahimpour Tags: FULL PAPER Source Type: research
