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(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 18, 2016 Category: Microbiology Source Type: news
Erratum
In the May 1, 2016 issue of Clinical Microbiology Newsletter, Vol. 38, No. 9, In the article “Polymyxin Susceptibility Testing: a Cold Case Reopened,” Table 2 on page 73 contained values for EUCAST intermediate breakpoints for colistin. In actuality, there are no such values; the correct Table 2 is shown below. We apologize for this error. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 18, 2016 Category: Microbiology Source Type: news
What Have We Done for You Lately? The Role of the American Society for Microbiology in Advancing Clinical Microbiology
This article outlines the breadth and scope of activities that ASM has and is working on to advance clinical microbiology. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 10, 2016 Category: Microbiology Authors: Susan E. Sharp, Lynn W. Enquist Source Type: news
Trueperella bernardiae Abscess Infection: a Case Report
Trueperella bernardiae was first characterized in 1987 by the Centers for Disease Control and Prevention (CDC) as a corynebacterium group 2 bacterium, as it was considered an uncommon pathogen, causing only opportunistic infections in compromised patients [1]. Only 15 cases of human infection have been reported since that time, which consist of urinary tract infections [2,3], joint infections [4–6], skin and soft-tissue infections [7,8], eye infection [9], necrotizing fasciitis [10], diabetic foot ulcer [11], bacteremia [7,8,12], and brain abscess [13]. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 10, 2016 Category: Microbiology Authors: Bobbie Rae F. VanGorder, Sally Sayed Ahmed, Russell A. Rawling, Paul A. Granato Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - June 10, 2016 Category: Microbiology Source Type: news
Microbiology of Middle Ear Infections: Do You Hear What I Hear?
Infectious conditions of the middle ear are a common and significant cause of morbidity and sometimes even mortality, especially in young children and elderly individuals. Pathogens and harmless commensal bacteria, viruses, and fungi co-inhabit the auditory canal and form intricate ecological networks, collectively known as a microbiome. Few studies that describe the normal flora of the middle ear have been published, and controversy exists about the roles of several possible pathogens. This review describes current literature examining otitis media and the roles various microbes play in the pathogenesis of middle ear infe...
Source: Clinical Microbiology Newsletter - May 17, 2016 Category: Microbiology Authors: Donna M. Wolk Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - May 17, 2016 Category: Microbiology Source Type: news
An Unusual Cause of Laryngotracheobronchitis
We present a case of pseudomembranous cryptococcal laryngotracheobronchitis in an 80-year-old woman with a history of intractable cough with production of long sputum strings and severe dysphonia. Her main risk factor was considered to be the use of high-dose inhaled fluticasone, given for severe mixed asthma/chronic obstructive pulmonary disease (COPD). This is an unusual presentation of pulmonary cryptococcal disease, which commonly presents as parenchymal disease. We also present a review of the published case reports of endobronchial and laryngeal cryptococcal disease. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - May 5, 2016 Category: Microbiology Authors: Vidthiya Menon, H.E. Jo, P. Corte, A.S. Lee, A.C. Wignall, H.K. Reddel Source Type: news
Polymyxin Susceptibility Testing: a Cold Case Reopened
In recent years, the emergence of multidrug-resistant Gram-negative rods and a dwindling antimicrobial armamentarium has led to renewed use of the polymyxins. With increasing use of polymyxins, there has been increase in resistance among previously susceptible populations of Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii. Unfortunately, susceptibility testing for the polymyxins is fraught with difficulties, making clinically informative interpretation of these tests challenging. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 21, 2016 Category: Microbiology Authors: Kurt H. Jerke, Mark J. Lee, Romney M. Humphries Source Type: news
Erratum
In the October 15, 2015 issue of Clinical Microbiology Newsletter (Vol. 37, No. 20), there were 2 errors in the article titled “Multiplexed Automated Digital Microscopy for Rapid Identification and Antimicrobial Susceptibility Testing of Bacteria and Yeast Directly from Clinical Samples.” In Tables 2 and 4 (pg. 166), the first line in the left-most column in both tables stated “Streptococcus aureus.” Both of these should have been “Staphylococcus aureus.” We apologize for this error. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 21, 2016 Category: Microbiology Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 21, 2016 Category: Microbiology Source Type: news
The Changing Landscape of Automation in the Practice of Diagnostic Medical Microbiology: But What about Safety?
The clinical microbiology laboratory is undergoing a transformation in diagnostic testing as result of entering the “machine” or “robotic” age with the development and availability of automation, primarily molecular-based multiplex instruments and total laboratory automation. Automation provides substantial benefits to the laboratory, administrators, clinician, and, ultimately, patient. Major benefits include faster and more accurate results, improved workflow efficiency, high-throughput testing, reduction of laboratory costs, reduction of human error, and, for the most part, saving valuable space. (Source: Clinica...
Source: Clinical Microbiology Newsletter - April 9, 2016 Category: Microbiology Authors: James W. Snyder Source Type: news
Misidentification of Brucella suis as Ochrobactrum anthropi in a Patient with Septic Arthritis
We report a case of a 24-year-old resident of North Queensland who presented to our facility with a native joint septic arthritis. A bacterial isolate recovered from an initial joint aspirate culture was misidentified as Ochrobactrum anthropi using an automated identification system. A subsequent specimen grew an isolate that was identified as Brucella sp. by the same automated system, with a single biochemical reaction (adonitol) differentiating the identities of the two organisms. Subsequent real-time PCR testing of the IS711 element of the Brucella genome confirmed both isolates as Brucella suis. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 9, 2016 Category: Microbiology Authors: Andrew Henderson, Gabriel See, Tom J. O'Donohoe, Chaw Aye, Fiona Parsonson, Cathy Engler, Robert Norton Tags: Case Report Source Type: news
Molecular Diagnosis in Resource-Limited Settings
The advantages of molecular testing for accurate diagnosis and optimal therapeutic management of patients infected with microorganisms is well established, yet many test methods are not feasible in underdeveloped or resource-limited settings. The disparity in testing methods is controversial from ethical, financial, and scientific perspectives. Over the years, philanthropic funding for early and accurate diagnosis has helped curtail the spread of disease and improved overall survival, yet infections caused by microorganisms are still the leading cause of death in the resource-limited parts of the world. (Source: Clinical M...
Source: Clinical Microbiology Newsletter - March 19, 2016 Category: Microbiology Authors: Camilla Rodrigues, Niyati Desai, Helen Fernandes Source Type: news
Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as a First-Line Diagnostic Modality in Bacterial Meningitis and Septicemia: a Report of Five Cases
The matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) technology has been shown to be a cost-effective, efficient, and reliable system for performing bacterial identifications. It has a number of potential advantages in clinical care. Here, we describe five life-threatening infections caused by either Listeria monocytogenes or Neisseria meningitidis that were diagnosed by using the MALDI-TOF MS system. The system proved particularly useful when the Gram-stained-smear results were misleading or inconclusive. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 19, 2016 Category: Microbiology Authors: Priya Nori, Wendy Szymczak, Connie Park, Philip Gialanella, Iona Munjal, Philip Chung, Yi Guo, Julie Williamson, Belinda Ostrowsky, Michael Levi Tags: Case Report Source Type: news
