Species Other than
Most clinicians and microbiologists are familiar with Bordetella pertussis, its associated clinical syndromes and treatment with antimicrobials, and both biochemical and molecular methods for identification. Many of the other Bordetella species are much less well known, though they do cause clinical disease in humans. Some, like Bordetella parapertussis and Bordetella holmesii, are common causes of respiratory disease (albeit mild) in individuals with no significant comorbidities; others, such as Bordetella trematum and Bordetella ansorpii, have been noted to cause disease only rarely, and always in immunocompromised hosts...
Source: Clinical Microbiology Newsletter - April 7, 2015 Category: Microbiology Authors: Jocelyn A. Srigley, David M. Goldfarb, Jeffrey M. Pernica Source Type: news
Acute Post-Cataract Endophthalmitis Caused by
Acute post-cataract surgery endophthalmitis is almost always caused by bacteria, although less commonly, fungi and mycobacteria have also been reported as agents of the infection. With an estimated incidence of 0.06 to 0.3%, endophthalmitis is the most serious complication of intraocular surgery, because it may result in a severe decrease of visual acuity or even blindness in the involved eye (1–5). In Western countries, coagulase-negative staphylococci are responsible for 70% of post-cataract endophthalmitis, followed by Staphylococcus aureus, viridans group streptococci, and other gram-positive bacteria. (Source: Clini...
Source: Clinical Microbiology Newsletter - April 7, 2015 Category: Microbiology Authors: Charlotte Trouvé, Rudolf Reyniers, Patrick Descheemaeker, Eric Nulens Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 7, 2015 Category: Microbiology Source Type: news
Blood Cultures: the Importance of Meeting Pre-Analytical Requirements in Reducing Contamination, Optimizing Sensitivity of Detection, and Clinical Relevance
The primary goal of the clinical microbiology laboratory is to provide reliable, timely, and clinically relevant diagnostic test results. Blood cultures are one of the most important specimens managed by the clinical microbiology laboratory and are the primary and most sensitive method for diagnosing blood stream infections (bacteremia, fungemia, and sepsis), in addition to influencing appropriate antimicrobial therapy. Of the three phases of laboratory testing, pre-analytical, analytical, and post-analytical, the former is the most challenging for the clinical microbiology laboratory to control. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 24, 2015 Category: Microbiology Authors: James W. Snyder Source Type: news
Left-Sided MRSA Endocarditis Successfully Treated with a Combination of Daptomycin and Ceftaroline
Vancomycin is the recommended drug for treating endocarditis caused by methicillin-resistant Staphylococcus aureus (MRSA). Daptomycin is not inferior to vancomycin for treating MRSA bacteremia and right-sided endocarditis. There is synergistic activity between daptomycin and ceftaroline. Fifty percent of all cases of bacterial endocarditis are caused by S. aureus, half of which are caused by methicillin-resistant strains (1). A retrospective review of 133 cases of S. aureus endocarditis indicated an overall mortality rate of 38% for left-sided endocarditis in comparison to 17% for right-sided endocarditis (2). (Source: Cli...
Source: Clinical Microbiology Newsletter - March 24, 2015 Category: Microbiology Authors: Claudia D. Jarrin Tejada, Richard P. Wenzel Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 24, 2015 Category: Microbiology Source Type: news
Infectious Meningitis
Infectious meningitis is a large public health concern, especially in children and immunocompromised patients. Although the epidemiology of meningitis has shown significant decline in past decades, partly due to the introduction of vaccines, outbreaks are still reported worldwide. Diagnosis of meningitis is of critical importance, and it is considered to be one of the most urgent of the microbiological medical emergencies. In order to improve the treatment strategy, various diagnostic methods have been developed to detect the presence of infectious agents that cause meningitis, as well as their antibiotic resistance patter...
Source: Clinical Microbiology Newsletter - March 7, 2015 Category: Microbiology Authors: AbdelRahman M. Zueter, Amani Zaiter Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 7, 2015 Category: Microbiology Source Type: news
and Pulmonary Infection in a Patient on Long-Term Steroid Treatment: Case Report and Literature Review
This article describes a very rare case of Aspergillus and Nocardia co-infection in a patient on long-term steroid therapy and reviews the clinical and epidemiologic characteristics associated with both opportunistic pathogens. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 17, 2015 Category: Microbiology Authors: Guldeep Uppal, Raghava Potula, Allan L. Truant Source Type: news
A Case of Endocarditis
We describe a rare case of vancomycin-resistant E. casseliflavus native-valve infective endocarditis. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 17, 2015 Category: Microbiology Authors: Scott W. Aesif, Mark Delman, John F. Keiser Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 17, 2015 Category: Microbiology Source Type: news
Current Status of Taxonomy and Recommended Identification Methods
The genus Nocardia has had a long and complex history with an equally complex taxonomy. Recent advances in molecular identification methods have vastly expanded the number of recognized Nocardia species, further complicating the taxonomy of the genus. Because of the increasing number of clinically relevant species, biochemical identification methods are no longer adequate to allow discrimination among species. Molecular methodologies, specifically gene sequencing, has now become the gold standard for nocardial identification. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 3, 2015 Category: Microbiology Authors: Barbara A. Brown-Elliott, Patricia Conville, Richard J. Wallace Source Type: news
ScienceDirect
(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 3, 2015 Category: Microbiology Source Type: news
A special invitation to Authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 3, 2015 Category: Microbiology Source Type: news
Affordable Health Care and the Business of Clinical Microbiology: It's All in the Delivery
In today's health care environment, laboratories are increasingly being asked to justify the acquisition of new technology. Justification is often done through a formal business case analysis. One important component of the business case is being able to show outcomes and impacts on patient care. Patient outcomes are becoming a focus of investigation following implementation of new technology and a key component to building a strong business case for that technology. Given that new technology is often more expensive than an add-on test to traditional work-ups, its true value is not fully appreciated unless it is evaluated ...
Source: Clinical Microbiology Newsletter - January 20, 2015 Category: Microbiology Authors: Elizabeth M. Marlowe, Susan M. Novak, Mark LaRocco Source Type: news
