A Case of Cholera Imported From Haiti
Cholera, caused by Vibrio cholerae, is an acute and sudden-onset diarrheal disease that can result in profound dehydration because of excessive loss of water and electrolytes. Severe infections, if untreated, can lead to hypovolemic shock and death within 18 to 24 h. The virulence of V. cholerae is due to the production of cholera toxin that binds to enterocytes and eventually leads to the activation of the CFTR (cystic fibrosis transmembrane conductance regulator) gene, resulting in the massive efflux of water and electrolytes into the small bowel. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 20, 2015 Category: Microbiology Authors: Eric M. Sachinwalla, Carolyn Fernandes, Raghava Potula, Ming Zhang, Byungse Suh, Allan L. Truant Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 20, 2015 Category: Microbiology Source Type: news
“Orange” You Glad You Checked the Buffy Coat?
The incidence of tick-borne human infectious syndromes has dramatically risen in the last 2 decades, leading to significant morbidity and mortality. The importance of a rapid and accurate diagnosis to distinguish anaplasmosis from other febrile illnesses is paramount for the prompt administration of appropriate antibiotics and is imperative for the successful treatment of the tick-borne infections. We summarize the current literature describing the biology, clinical presentation, and epidemiology of human granulocytic anaplasmosis. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 14, 2015 Category: Microbiology Authors: Joseph D. Cooper, Dan Dometita, Anjum Hasan, Patrick Dorion, Donna M. Wolk, Raquel M. Martinez Source Type: news
A Case of Lemierre's Syndrome Caused by Initially Identified as Group C Streptococcus
We report a rare case of Lemierre's syndrome in a previously healthy 21-year-old male caused by Streptococcus anginosus, initially identified as a group C Streptococcus. The only other case of Lemierre's syndrome caused by group C Streptococcus may have been misidentified (1). (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 14, 2015 Category: Microbiology Authors: Diana Otero, Martin Gnoni, James W. Snyder, Forest W. Arnold Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 14, 2015 Category: Microbiology Source Type: news
: Revisitation of an Enduring Human Pathogen
Yersinia enterocolitica remains a charismatic microorganism. The research findings outlined in this article have uncovered new virulence factors, such as type III secretion systems, and have advanced our understanding of the pathogenesis of gastrointestinal infections caused by Y. enterocolitica. Furthermore, a clarification of the potential capability of biovar 1A strains, long regarded as avirulent, has now proven that they cause symptomatic infections in appropriate patient settings, such as immunosuppression or hemochromatosis. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - December 23, 2014 Category: Microbiology Authors: Edward J. Bottone Source Type: news
Serologic Testing for Syphilis: Benefits and Challenges of a Reverse Algorithm
Syphilis is a human infection of global importance. Its diagnosis can be challenging, requiring construction of a serologic profile based on the results of at least two types of antibody tests: treponemal and nontreponemal. The traditional approach to the serodiagnosis of syphilis has been the use of a nontreponemal screening assay followed by the performance of a treponemal confirmatory test if the initial nontreponemal screening test was reactive. With the increasing availability of automated, easier-to-perform, and rapid treponemal assays, an increasing number of laboratory testing sites are adopting reverse sequence sc...
Source: Clinical Microbiology Newsletter - December 7, 2014 Category: Microbiology Authors: Katherine Soreng, Roma Levy, Yetunde Fakile Source Type: news
Index to CMN Volume 36, 2014
(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - December 7, 2014 Category: Microbiology Source Type: news
Cost Avoidance and Outcome Improvement by Implementing a Test Utilization Strategy for Molecular Microbiology Tests
Test utilization is an essential strategy in the clinical laboratory, especially with increasing numbers of tests and health care costs. We designed a triage system for molecular microbiology tests ordered from 2007 through 2010 to assess their appropriateness before they were sent out to a reference laboratory for testing. The number of tests ordered and approved and the number with positive results were calculated during the study period. Cost avoidance was subsequently calculated. A total of 13,839 tests were ordered, averaging 3,335 tests/year. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 21, 2014 Category: Microbiology Authors: Jessica Ricaldi, Lori Racsa, Tobias Pusch, Rita M. Gander, Paul Southern, Dominick Cavuoti, Linda Byrd, Adnan Alatoom Source Type: news
A Special Invitation to Authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 21, 2014 Category: Microbiology Source Type: news
New Kids on the Block Causing Gastroenteritis: Bugs You Need To Look For
Currently, there are over 30 recognized or reputed bacterial agents that are regarded as causes of gastroenteritis. Most clinical microbiology laboratories test for only the most common enteric pathogens. However, three newer bacterial agents, Providencia alcalifaciens, Escherichia albertii, and Klebsiella oxytoca, are worthy of attention and consideration because of their ability to cause diarrhea and outbreaks of infection. In addition, these three bacterial agents possess virulence factors that can produce severe disease. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 9, 2014 Category: Microbiology Authors: Errin Rider, Sharon L. Abbott, J. Michael Janda Source Type: news
Native Valve Endocarditis
Lactococcus garvieae is regarded as a veterinary pathogen, causing hemorrhagic septicemia in fish (1) and mastitis in cows (2). The organism has also been recovered from a variety of dairy products, such as unpasteurized milk (3) and cheese (4–6), as well as various meat products (5,6). L. garvieae is an uncommon cause of human infection, with only a limited number of cases reported worldwide (7–20). Most infections involve either native (7–11) or prosthetic (12–15) heart valves, but cases of osteomyelitis (16–17), hepatic abscess (18), and septicemia (19) have also been documented. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 9, 2014 Category: Microbiology Authors: Russell A. Rawling, Paul A. Granato Tags: Case Report Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - November 9, 2014 Category: Microbiology Source Type: news
The Genus – Part II: New Species and Pathogens in the “Miscellaneous” Streptococci and “Viridans” Streptococci Groups
In the second part of this two-part series on an update on the streptococci, new species and emergent human pathogens in the “viridans streptococci” and the “miscellaneous streptococci” groups are discussed. Among the “miscellaneous streptococci,” the most important organism in human infectious diseases is Streptococcus suis. This organism is primarily an agent of disease in swine and other animals and has now emerged as a significant human pathogen, causing bacteremia and meningitis, particularly among populations in Asia and the Far East. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - October 28, 2014 Category: Microbiology Authors: William M. Janda Source Type: news
Statement of Ownership
(Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - October 28, 2014 Category: Microbiology Source Type: news
