Clinical Microbiology Q & A – Question
Question: (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 24, 2017 Category: Microbiology Source Type: news

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Source: Clinical Microbiology Newsletter - March 24, 2017 Category: Microbiology Source Type: news

Clinical Microbiology Q & A – Answer
Answer: (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 24, 2017 Category: Microbiology Source Type: news

Mycobacterium chimaera: Coming out of Nowhere to Dominate 2016 Infection Prevention Discussions
Mycobacterium chimaera is a bacterium of the 21st century. The organism was named in 2004 when molecular assays showed it to belong to the Mycobacterium avium complex. More specifically, it was found to be a close relative of Mycobacterium intracellulare. Merely a decade later, M. chimaera turned out to be the cause of infections associated with heater-cooler units used during open-heart surgery. There are still less than 100 confirmed cases worldwide, but the mycobacterial species has captured the attention of patients and caregivers alike because many of these infections are manifested months to years following surgery. ...
Source: Clinical Microbiology Newsletter - March 7, 2017 Category: Microbiology Authors: Fran Schaeffer, Brooks Kennedy, Nehemiah Landes, Ernest Trevino, Paula Vance, Alice S. Weissfeld Source Type: news

Strongyloides stercoralis Hyperinfection Causing Abdominal Pain and Hypoxia
Strongyloides stercoralis is an intestinal nematode with the unique ability to replicate within humans, resulting in autoinfection. Strongyloides can cause a hyperinfection or disseminated disease that typically occurs in immunocompromised individuals [1]. Our case was unique in that our patient developed disseminated strongyloidiasis in the absence of any immunocompromising risk factors. Her initial Strongyloides infection probably resulted in an autoinfection that subsequently led to hyperinfection with severe gastrointestinal and pulmonary complications. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 7, 2017 Category: Microbiology Authors: Rebecca Rawl, Linda Matthews, Robert L. Sautter, Martin Scobey Tags: Case Report Source Type: news

A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 7, 2017 Category: Microbiology Source Type: news

“Did I Hear You Correctly? The Organism Identified Was Corynebacterium diphtheriae?”
Diphtheria is a bacterial infection caused by Corynebacterium diphtheriae and is primarily transmitted from person to person through close physical and respiratory contact; disease can involve almost any mucous membrane and is classified depending on the anatomic site of infection. Diphtheria is an acute, toxin-mediated disease whose occurrence is characterized by periodicity and epidemic waves, with a high incidence and mortality. Once one of the leading causes of childhood death, global diphtheria incidence declined approximately 70% through implementation of widespread vaccination programs. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 18, 2017 Category: Microbiology Authors: Betty A. Forbes Source Type: news

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Source: Clinical Microbiology Newsletter - February 18, 2017 Category: Microbiology Source Type: news

Come in Out of the Cold: Alternatives to Freezing for Microbial Biorepositories
Biorepositories are “libraries” in which biospecimens, bacteria, or DNA and RNA extracts are stored for either clinical or research purposes. Such specimens enable modern molecular-based research and could support method verification, validation, quality control, and, in some cases, proficiency testing in clinical laboratories. Cryopreservation of extracted nucleic acids ensures the stability and longevity of DNA and RNA from patient samples, with the most common methods used for long-term storage of samples being the use of −80°C freezers or liquid nitrogen. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 4, 2017 Category: Microbiology Authors: Erica Isaacs, Monika Schmelz Source Type: news

Erratum
In the “Clinical Microbiology Q& A ” feature which appeared in the January 1, 2017 issue of CMN (Vol. 39, No. 1), the correct answer listed on page 10 is (a), NOT (d). We apologize for this error. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 4, 2017 Category: Microbiology Source Type: news

Listeria monocytogenes Contamination of Ice Cream: a Rare Event That Occurred Twice in the Last Two Years
The Centers for Disease Control and Prevention (CDC) estimates that approximately 1,600 illnesses and 260 deaths due to Listeria monocytogenes occur annually in the United States. Most of these infections are caused by ingestion of contaminated food. The most common foods are soft cheeses, deli meats, hot dogs, raw milk, packaged salads, and cantaloupes. Thus, it was unusual for infections to occur from ice cream manufactured by Blue Bell Creameries of Brenham, Texas, in 2015, and it was even more unusual that a second ice cream manufacturer, Jeni's Splendid Ice Creams based in Columbus, Ohio, isolated L. (Source: Clinical...
Source: Clinical Microbiology Newsletter - January 20, 2017 Category: Microbiology Authors: Alice S. Weissfeld, Nehemiah Landes, Hannah Livesay, Ernest Trevino Source Type: news

Disseminated Nocardia farcinica Infection in a Patient with Steroid-dependent Autoimmune Hemolytic Anemia: Case Report and Literature Review
We describe a 64-year-old female with autoimmune hemolytic anemia (AIHA) who was steroid dependent and on cyclosporine immunosuppressive therapy. Nocardia farcinica was recovered from the patient's bronchoalveolar lavage (BAL) specimen and several blood cultures. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 20, 2017 Category: Microbiology Authors: Zeti Norfidiyati Ayub, Habsah Hasan, Mohd Zulfakar Mazlan, Alwi Muhd Besari Tags: Case Report Source Type: news

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Source: Clinical Microbiology Newsletter - January 20, 2017 Category: Microbiology Source Type: news

A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 20, 2017 Category: Microbiology Source Type: news

Postpartum Streptococcus pyogenes Outbreak in the Labor and Delivery Unit of a Quaternary Referral Center: a Case Series and Review of the Literature
Historically, childbirth was associated with morbidity and mortality, often due to endometritis or puerperal fever. Streptococcus pyogenes was first identified as the cause of puerperal fever by Louis Pasteur, and it remains a virulent and lethal pathogen with a case fatality rate of 15 to 20% [1]. The pathogenesis of postpartum endometritis is believed to be associated with disruption of the woman's mucosal barriers from childbirth and invasion of bacteria either from vaginal flora or from a health care worker's hands [2]. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 4, 2017 Category: Microbiology Authors: Joseph David Cooper, Surya Ram Cooper, Donna M. Wolk, Ann Marie Tice, Tamara F. Persing, Lisa Marie Esolen Source Type: news