Science with Societal Implications: Detecting Mycobacterium tuberculosis in Africa
This report provides a summary of the Xpert technology and both the benefits and challenges of its implementation as a POC test in resource-limited settings. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - May 5, 2014 Category: Microbiology Authors: Aubri S. Carman, Arpita G. Patel Tags: Lead Article Source Type: news
Letter to the Editors
In the article entitled “Sniff the Plates? Laboratory Exposure to Burkholderia pseudomallei” in the February 15, 2013 issue of Clinical Microbiology Newsletter (CMN Vol. 35, No. 4), Knost et al. () reported a case of melioidosis in a 27-year-old-male. After reading the article, we note the need for a number of clarifications that we would like to bring to the attention of the CMN readership. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 28, 2014 Category: Microbiology Authors: Tina J. Benoit, David D. Blaney Tags: Letter to the Editors Source Type: news
Streptococcus pseudopneumoniae
Abstract:
Streptococcus pseudopneumoniae is a novel species belonging to the viridans group streptococci (VGS). Accurate species identification is challenging due to significant homology to other VGS. Whole-genome sequencing of S. pseudopneumoniae suggests it most likely originated from Streptococcus pneumoniae, sharing many of its virulence genes. There are several limitations when using traditional phenotypic identification methods to identify this organism. Other identification approaches include genotypic methods, pherotype analysis, and matrix-assisted laser desorption ionization–time of flight mass spectrometr...
Source: Clinical Microbiology Newsletter - April 28, 2014 Category: Microbiology Authors: Sophie C.H. Wen, Trevor Anderson, David Murdoch Tags: Lead Article Source Type: news
Human Papillomavirus-Associated Esophageal Ulcer in a Patient with HIV Infection
We present a case of esophageal human papilloma-virus (HPV) infection in an HIV-infected male, which was diagnosed by histologic examination of a biopsy specimen collected at endoscopy. The lesion resolved after institution of triple-antiretroviral therapy. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - April 11, 2014 Category: Microbiology Authors: Rafael Hernán Navarrete-Sandoval, Tiburcio Margarito Santos-González, César Rivera-Benitez Tags: Case Report Source Type: news
Occupy Call Street? Reconsidering a Microbiology Critical Action Value Policy
Critical action value (CAV) policies for microbiology test results are regulated by the same mandates that govern critical values for other laboratory testing. Policy revisions and updates are left to the discretion of laboratory directors, in conjunction with their clinical communities. The published literature on CAV policy has limited discussion of infectious disease testing, necessitating the use of other information as a guide. The reconsideration of one's CAV policy benefits from an organized approach and the recognition and reconciliation of different perspectives and resources. A recent experience and consideration...
Source: Clinical Microbiology Newsletter - April 11, 2014 Category: Microbiology Authors: Nancy S. Miller Tags: Lead Article Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 28, 2014 Category: Microbiology Source Type: news
A Case of Tuberculosis Presenting as a Perianal Abscess
Extrapulmonary tuberculosis (TB) accounts for 5 to 15% of TB cases (). TB of the gastrointestinal (GI) tract is estimated to occur in 1% of all TB cases and in 12% of cases of extraintestinal TB (), representing the sixth most frequent anatomic site of TB infection outside of the lung (). Importantly, any portion of the GI tract from the esophagus to the anus may be involved, with the ileocecal region being the most frequent (). This case report describes a patient with a perianal abscess that grew Mycobacterium tuberculosis and who also had cavitary lung disease. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 28, 2014 Category: Microbiology Authors: Joe Dylewski Tags: Case Report Source Type: news
Forensic Microbiology
This article discusses some of the roles that microbiology plays in forensic science. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - March 28, 2014 Category: Microbiology Authors: Donald C. Lehman Tags: Lead Article Source Type: news
The Microbe Farms: Microbial Biorepositories in Clinical Microbiology
Abstract:
Biorepositories aim to acquire, authenticate, preserve, develop, and distribute biological specimens, along with information, technology, intellectual property, and standards for the advancement and application of scientific knowledge. Biorepositories are critical components of modern healthcare, as they provide resources to advance translational biomedical research, navigation through the FDA process for in vitro devices, verification and validation of diagnostic methods, and personalized medicine. In order to fully realize the opportunities that biorepositories offer to medicine, laboratories must be able ...
Source: Clinical Microbiology Newsletter - March 7, 2014 Category: Microbiology Authors: Aubrey Cunningham, Raquel M. Martinez, Diana R. Hernandez, Donna M. Wolk Tags: Lead Article Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 21, 2014 Category: Microbiology Source Type: news
In Pursuit of a Stealth Pathogen: Laboratory Diagnosis of Bartonellosis
This article provides an overview of diseases caused by members of the genus Bartonella and the mechanisms of pathogenesis. The laboratory diagnosis of bartonellosis relies on three primary methods. This article examines the evolution of culture techniques, serology, and nucleic acid amplification tests used to detect Bartonella spp. in clinical specimens and suggests areas for future research to improve laboratory diagnostics. In this way, a better understanding of the epidemiology of bartonellosis can be achieved. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 21, 2014 Category: Microbiology Authors: Leslie A. Wolf, Natalie A. Cherry, Ricardo G. Maggi, Edward B. Breitschwerdt Source Type: news
A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 7, 2014 Category: Microbiology Source Type: news
Urinary Tract Sepsis Caused by Lactococcus garvieae
This report describes the first case of bacteremia caused by the organism as a complication of urological surgery. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 7, 2014 Category: Microbiology Authors: Joe Dylewski Source Type: news
Shewanella: a Marine Pathogen as an Emerging Cause of Human Disease
This report provides an overall update on this increasingly reported genus as an emerging cause of human infectious disease. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - February 7, 2014 Category: Microbiology Authors: J. Michael Janda Source Type: news
Cutaneous Leishmaniasis in a Central American Refugee
We report a case of cutaneous leishmaniasis in a 49-year-old male who presented to our emergency room for evaluation of an ulcerative lesion on his finger. Microscopic examination of a Giemsa-stained touch preparation from the finger lesion showed intracellular protozoa suggestive of Leishmania species. The protozoan was recovered by culture from a biopsy specimen, and its identity was subsequently confirmed as Viannia (Leishmania) panamensis by using molecular methods. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 23, 2014 Category: Microbiology Authors: Helen Jacoby, Russell A. Rawling, Paul A. Granato Source Type: news
