A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - October 11, 2013 Category: Microbiology Source Type: news

The oral microbiome: Its role in health and in oral and systemic infections
Abstract: The oral cavity harbors a rich and diverse microflora, which is mostly found within biofilms attached to the various soft- and hard-tissue surfaces. Recent studies using molecular methods have revealed previously unrecognized species within biofilms associated with health and several common oral diseases. These unrecognized species established an under-appreciated diversity within the flora, with new questions to be answered. Information regarding the composition of the oral microbiome associated with oral health, dental caries, periodontal disease, and endodontic infection is briefly reviewed. Recent concep...
Source: Clinical Microbiology Newsletter - October 11, 2013 Category: Microbiology Authors: Frank A. Scannapieco Source Type: news

Management of labor and infection control practices in a Q fever-infected patient
We present a case of a 30-year-old patient who was diagnosed with Q fever at about 26 weeks of pregnancy (). She was partially treated with cotrimoxazole for 2 weeks, but therapy was discontinued because she developed a drug allergy and refused further antibiotic treatment. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - September 27, 2013 Category: Microbiology Authors: Murugesh Jagadeesan, Shrikant Ambalkar, Michael Collins, Shanti Chidambaram, Diane Simpson, Lisa Bree Source Type: news

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for the identification of bacterial and fungal isolates
Abstract: Identification of bacterial and fungal isolates from clinical specimens has traditionally been performed by examination of colony morphology and by biochemical characterization using classic tube sets. While these methods remain the gold standard for identification, they can be laborious to perform and subjective to interpret. These drawbacks have largely been alleviated with the advent of automated biochemical testing platforms and with the development of DNA sequencing and polymerase chain reaction techniques. Though reliable and rapid, molecular-based platforms are associated with significantly higher cos...
Source: Clinical Microbiology Newsletter - September 27, 2013 Category: Microbiology Authors: Elitza S. Theel Source Type: news

Isolation of Advenella kashmirensis from a Diabetic Foot Wound
We describe the first case of human infection caused by Advenella kashmirensis. The patient had a history of diabetes mellitus type 2 and presented with a diabetic ulcer on the top of the big toe of the left foot. On the basis of the clinical presentation of the toe ulcer, the histologic appearance of tissue obtained at biopsy, and the microbiological culture results, the patient was diagnosed with a wound infection caused by A. kashmirensis. The patient experienced a favorable outcome following 42 days of oral ciprofloxacin therapy. The patient most likely acquired his infection from an environmental source, because A. ka...
Source: Clinical Microbiology Newsletter - September 15, 2013 Category: Microbiology Authors: Wim Maurissen, Joris Meeuwissen, Kevin Martens, Jozef Tits, Els Oris, Jan Verhaegen, Guy Coppens Source Type: news

Use of Proficiency Testing as a Tool to Improve Quality in Microbiology Laboratories
Abstract: Proficiency testing (PT) is a valuable tool for assessing laboratory performance and verifying the accuracy and reliability of test results. Participation is required by the Clinical Laboratory Improvement Amendments (CLIA) of 1988 for each of the microbiology subspecialties (bacteriology, mycobacteriology, mycology, parasitology, and virology), and the regulations include specific PT requirements for each subspecialty. To determine the use and perceived value of PT beyond meeting CLIA requirements, the Centers for Disease Control and Prevention funded a cooperative agreement with the Association of Public H...
Source: Clinical Microbiology Newsletter - September 15, 2013 Category: Microbiology Authors: Heather L. Stang, Nancy L. Anderson Source Type: news

Isolation of Advenella kashmirensis from a Diabetic Foot Wound
We describe the first case of human infection caused by Advenella kashmirensis. The patient had a history of diabetes mellitus type 2 and presented with a diabetic ulcer on the top of the big toe of the left foot. On the basis of the clinical presentation of the toe ulcer, the histologic appearance of tissue obtained at biopsy, and the microbiological culture results, the patient was diagnosed with a wound infection caused by A. kashmirensis. The patient experienced a favorable outcome following 42 days of oral ciprofloxacin therapy. The patient most likely acquired his infection from an environmental source, because A. ka...
Source: Clinical Microbiology Newsletter - September 9, 2013 Category: Microbiology Authors: Wim Maurissen, Joris Meeuwissen, Kevin Martens, Jozef Tits, Els Oris, Jan Verhaegen, Guy Coppens Source Type: news

Use of Proficiency Testing as a Tool to Improve Quality in Microbiology Laboratories
Abstract: Proficiency testing (PT) is a valuable tool for assessing laboratory performance and verifying the accuracy and reliability of test results. Participation is required by the Clinical Laboratory Improvement Amendments (CLIA) of 1988 for each of the microbiology subspecialties (bacteriology, mycobacteriology, mycology, parasitology, and virology), and the regulations include specific PT requirements for each subspecialty. To determine the use and perceived value of PT beyond meeting CLIA requirements, the Centers for Disease Control and Prevention funded a cooperative agreement with the Association of Public H...
Source: Clinical Microbiology Newsletter - September 9, 2013 Category: Microbiology Authors: Heather L. Stang, Nancy L. Anderson Source Type: news

A Special Invitation to Authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 29, 2013 Category: Microbiology Source Type: news

A rare case of Lemierre's syndrome caused by methicillin-resistant Staphylococcus aureus in a facial abscess
Lemierre's syndrome, also known as postanginal sepsis, is characterized by unilateral jugular vein thrombosis; bacteremia, most often due to Fusobacterium necrophorum; and septic pulmonary emboli. Clinically, patients present with a severe sore throat, followed by fever and anterior cervical neck pain over the jugular vein. Most cases involve young healthy adults, but persons of any age may be affected. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 29, 2013 Category: Microbiology Authors: Joshua Rein, Sikhminder Sahansra, Anita Jose, Burke A. Cunha Source Type: news

The many facets of drug susceptibility testing for Mycobacterium tuberculosis
This article summarizes the epidemiology of tuberculosis and presents an appraisal of the currently available phenotypic and genotypic methods for detecting drug resistance. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 29, 2013 Category: Microbiology Authors: Ellen Jo Baron Source Type: news

A special invitation to authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 12, 2013 Category: Microbiology Source Type: news

Typhoid presenting as acute cerebellar ataxia
Typhoid fever, also called typhoid, is caused by Salmonella enterica serovar Typhi and Salmonella enterica serovar Paratyphi, both of which are acquired by ingestion of contaminated food and water. The global disease burden is approximately 21 million cases annually, with nearly 216,510 deaths reported during the year 2000 (). The clinical presentations of typhoid fever are variable, ranging from isolated high-grade fever to focal organ involvement. Approximately 10% of untreated cases of typhoid fever develop complications, and among these, atypical neurological manifestations can present as headache, delirium, typhoid me...
Source: Clinical Microbiology Newsletter - August 12, 2013 Category: Microbiology Authors: Moiz Salahuddin, Muhammad Qamar Masood Source Type: news

Pediatric HIV: Current recommendations for diagnosis and treatment
This article reviews our current knowledge and recommendations regarding the pathogenesis, diagnosis, treatment, and prevention of HIV in the pediatric population. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 12, 2013 Category: Microbiology Authors: Summer Donovan Source Type: news

A Special Invitation to Authors
The editors of Clinical Microbiology Newsletter welcome proposals for review articles on topics relevant to clinical microbiologists and infectious disease physicians. If you would like to prepare a brief manuscript on such a topic, please contact Paul Granato with your proposal (see contact information and general guidelines below) to discuss the details of the potential submission. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - July 24, 2013 Category: Microbiology Source Type: news