Veterinary and Comparative Oncology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Canine nodal marginal zone lymphoma: Descriptive insight into the biological behaviour
Canine nodal marginal zone lymphoma (nMZL) is classified as an indolent lymphoma. Such lymphomas are typified by low mitotic rate and slow clinical progression. While the clinical behaviour of canine splenic MZL has been described, characterized by an indolent course and a good prognosis following splenectomy, there are no studies specifically describing nMZL. The aim of this study was to describe the clinical features of and outcome for canine nMZL. Dogs with histologically confirmed nMZL undergoing a complete staging work‐up (including blood analysis, flow cytometry [FC] on lymph node [LN], peripheral blood and bone ma...
Source: Veterinary and Comparative Oncology - December 1, 2017 Category: Veterinary Research Authors: M. Cozzi, L. Marconato, V. Martini, L. Aresu, F. Riondato, F. Rossi, D. Stefanello, S. Comazzi Tags: ORIGINAL ARTICLE Source Type: research
Outcome of 9 dogs treated with stereotactic radiation therapy for primary or metastatic vertebral osteosarcoma
Primary and metastatic vertebral osteosarcoma (OSA) in the dog carries an overall guarded prognosis. Previously reported definitive treatments in dogs with vertebral OSA have included surgery, radiotherapy, chemotherapy or a combination of those therapies. This retrospective study was completed to determine patterns of failure, duration of local control and survival time in dogs with vertebral OSA treated with stereotactic radiation therapy (SRT). Nine dogs were treated with SRT for vertebral OSA. Protocols ranged from 1 to 5 fractions with total prescription ranging from 13.5 to 36 Gy. Six dogs had primary lesions and 3...
Source: Veterinary and Comparative Oncology - November 28, 2017 Category: Veterinary Research Authors: K. E. Swift, S. M. LaRue Tags: ORIGINAL ARTICLE Source Type: research
Vitamin D receptor expression in canine mammary gland and relationship with clinicopathological parameters and progesterone/oestrogen receptors
The vitamin D receptor (VDR) belongs to the nuclear class II receptor family. VDR is a ligand transcription factor and mediates the actions of calcitriol, the active product of vitamin D synthesis. Nowadays, it is known that the biological actions of calcitriol include the capacity to modulate cancer features, such as proliferation and differentiation, apoptosis, angiogenesis, invasion and metastasis. VDR expression has been demonstrated in human breast cancer and vitamin D has emerged as a promising targeted therapy. We analyse the VDR expression in normal and neoplastic canine mammary tissue samples and its relationship ...
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Authors: R. S ánchez‐Céspedes, M. D. Fernández‐Martínez, A. Raya, C. Pineda, I. López, Y. Millán Tags: ORIGINAL ARTICLE Source Type: research
The role of sentinel lymph node mapping in small animal veterinary medicine: A comparison with current approaches in human medicine
Veterinary and Comparative Oncology, EarlyView. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
Vitamin D receptor expression in canine mammary gland and relationship with clinicopathological parameters and progesterone/oestrogen receptors
Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E185-E193, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
Outcome of 9 dogs treated with stereotactic radiation therapy for primary or metastatic vertebral osteosarcoma
Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E152-E158, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
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Veterinary and Comparative Oncology, Ahead of Print. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
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Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E185-E193, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
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Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E152-E158, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Source Type: research
The role of sentinel lymph node mapping in small animal veterinary medicine: A comparison with current approaches in human medicine
The relevance of regional lymph node (LN) assessment to quantify the metastatic spread of cancer is well recognized in veterinary oncology. Evaluation of LNs is critical for tumour staging. However, sampling the correct LN may not be possible without sentinel lymph node (SLN) mapping. Methods for diagnostic imaging and intraoperative detection of SLNs are well established in human medicine, in particular, the combination of lymphoscintigraphy and intraoperative application of blue dyes. Nevertheless, alternative imaging techniques are available and have gained increasing interest. Successful implementation of these techniq...
Source: Veterinary and Comparative Oncology - November 27, 2017 Category: Veterinary Research Authors: P. Beer, A. Pozzi, C. Rohrer Bley, N. Bacon, N. S. Pfammatter, C. Venzin Tags: REVIEW ARTICLE Source Type: research
Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers
Non‐adherent, 3‐dimensional sphere formation is used as an in vitro surrogate to evaluate cellular potential for tumour initiation and self‐renewal. To determine if a shared molecular program underlies the capacity for sphere formation by cells originating from diverse tumour types, we characterized molecular and functional properties of 10 independent cell lines derived from 3 ontogenetically distinct dog cancers: hemangiosarcoma, osteosarcoma and glial brain tumours. Genome‐wide gene expression profiling identified tumour‐of‐origin‐dependent patterns of adjustment to sphere formation in a uniform culture co...
Source: Veterinary and Comparative Oncology - November 20, 2017 Category: Veterinary Research Authors: J. ‐H. Kim, A. M. Frantz, A. L. Sarver, B. H. Gorden Klukas, M. Lewellen, T. D. O'Brien, E. B. Dickerson, J. F. Modiano Tags: ORIGINAL ARTICLE Source Type: research
Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers
Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E176-E184, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 20, 2017 Category: Veterinary Research Source Type: research
Faecal microbiota in dogs with multicentric lymphoma
Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E169-E175, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 20, 2017 Category: Veterinary Research Source Type: research
Retrospective analysis of factors affecting clinical outcome following CHOP ‐based chemotherapy in dogs with primary nodal diffuse large B‐cell lymphoma
Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E159-E168, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 20, 2017 Category: Veterinary Research Source Type: research
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Veterinary and Comparative Oncology,Volume 16, Issue 1, Page E176-E184, March 2018. (Source: Veterinary and Comparative Oncology)
Source: Veterinary and Comparative Oncology - November 20, 2017 Category: Veterinary Research Source Type: research
