Indexing cardiovascular and respiratory variables: allometric scaling principles
ConclusionsIndexing of cardiopulmonary variables is commonly used in attempts to account for the effects of body size on measurements and to standardize them. Some cardiopulmonary variables have been indexed using various functions of body mass in a process that often ignores the underlying relationship between the variable of interest and body size, as described in the allometry literature. This can result in a failure to ideally reduce the effect of body size on measurements in a manner that highlights differences. We review how commonly measured cardiopulmonary variables are related to body mass in mammalian species acc...
Source: Veterinary Anaesthesia and Analgesia - May 29, 2015 Category: Veterinary Research Authors: Bruno H Pypendop, James H Jones Tags: Review Article Source Type: research

A combination of alfaxalone and medetomidine followed by an alfaxalone continuous rate infusion in cynomolgus monkeys (Macaca fascicularis) undergoing pharmacoMRS
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 5, 2015 Category: Veterinary Research Authors: Daniela Casoni, Eva M Amen, Mathieu Brecheisen, Basil Kuennecke, Thomas Müggler, Alessandra Bergadano Tags: Letter to the Editor Source Type: research

Transnasal administration of a combination of dexmedetomidine, midazolam and butorphanol produces deep sedation in New Zealand White rabbits
Conclusion and clinical relevanceThe TN route is a reliable and effective means for administration of DEX, MID and BUT to rabbits. The overall profound sedative effects and analgesic proprieties of the DMB combination can be selectively reversed depending on the needs of the procedure. Oxygen supplementation and careful monitoring are mandatory even in healthy subjects. The DMB protocol should be cautiously used in rabbits with cardiovascular or respiratory deficiencies. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Bruna Santangelo, Fabiana Micieli, Tiziana Mozzillo, Fabiana Reynaud, Francesco Marino, Luigi Auletta, Giancarlo Vesce Tags: Short Communication Source Type: research

The effect of two different intra‐operative end‐tidal carbon dioxide tensions on apnoeic duration in the recovery period in horses
Conclusions and clinical relevanceAiming to maintain intra‐operative Pe′CO2 at 60 ± 5 mmHg (8.0 ± 0.7 kPa) in mechanically ventilated horses resulted in more rapid RSV compared with when Pe′CO2 was maintained at 40 ± 5 mmHg (5.3 ± 0.7 kPa). (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Kate R Thompson, David Bardell Tags: Research Paper Source Type: research

Comparison of anesthesia with a morphine–lidocaine–ketamine infusion or a morphine–lidocaine epidural on time to extubation in dogs
Conclusions and clinical relevanceAdministration of MLK at the doses reported in this study did not prolong the time to extubation in comparison with a morphine–lidocaine epidural nerve block. The results indicate that concern over prolonging the time to extubation is not a reason to avoid the administration of MLK. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Erin Wendt‐Hornickle, Lindsey BC Snyder Tags: Short Communication Source Type: research

Mechanical nociceptive thresholds using four probe configurations in horses
Conclusions and clinical relevanceThe PC has nonlinear effects on MT. Therefore, it is important to define PC when measuring MT. Smaller probe tips may be preferable as MT data are less variable. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Polly M Taylor, Nadia Crosignani, Carlize Lopes, Ademir C Rosa, Stelio PL Luna, José NP Puoli Filho Tags: Research Paper Source Type: research

Stress‐related biomarkers in dogs administered regional anaesthesia or fentanyl for analgesia during stifle surgery
Conclusions and clinical relevanceAnalgesia with a peripheral nerve block or spinal anaesthesia prevented the glycaemic and cortisol responses to surgery, promoted better recovery quality, and decreased postoperative pain scores compared with FEN. In the present study, the regional anaesthesia techniques used were found to be excellent alternatives to fentanyl administration. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Marta Romano, Diego A Portela, Gloria Breghi, Pablo E Otero Tags: Research Paper Source Type: research

Cardiopulmonary arrest in a cat as a result of a suspected anaphylactic reaction to an intravenously administered iodinated contrast agent
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Diego Rodrigo‐Mocholí, Annelies Willems, Stijn Schauvliege, Tim Bosmans Tags: Letter to the Editor Source Type: research

Effects of acepromazine or dexmedetomidine on fentanyl disposition in dogs during recovery from isoflurane anesthesia
Conclusions and clinical relevanceThe dose rates of fentanyl used in this study achieved previously established analgesic plasma concentrations for the duration of the infusion. Despite alterations in fentanyl pharmacokinetics, differences in fentanyl plasma concentrations among treatments during recovery from anesthesia were small and were unlikely to be of clinical significance. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Stephanie Keating, Carolyn Kerr, Wayne McDonell, Alexander Valverde, Ron Johnson, Heather Knych, Andrea Edginton Tags: Research Paper Source Type: research

The minimum alveolar concentration of sevoflurane in ring‐tailed lemurs (Lemur catta) and aye‐ayes (Daubentonia madagascariensis)
Conclusions and clinical relevanceThe sevoflurane MAC was significantly higher in ring‐tailed lemurs, compared to aye‐ayes. The MAC of sevoflurane in aye‐ayes is consistent with reported MAC values in other species. Extrapolation of sevoflurane anesthetic dose between different species of lemurs could lead to significant errors in anesthetic dosing. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - May 1, 2015 Category: Veterinary Research Authors: Sathya K Chinnadurai, Cathy Williams Tags: Short Communication Source Type: research

Cardiorespiratory parameters in the awake pigeon and during anaesthesia with isoflurane
Conclusions and clinical relevanceIsoflurane MAC in pigeons appeared to be higher than in other avian species. Isoflurane anaesthesia in pigeons resulted in hypercapnia, hypotension, mild hypothermia and second‐ and third‐degree atrioventricular blocks. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - April 30, 2015 Category: Veterinary Research Authors: Julie Botman, Alex Dugdale, Fabien Gabriel, Jean‐Michel Vandeweerd Tags: Research Paper Source Type: research

Agreement between veterinary students and anesthesiologists regarding postoperative pain assessment in dogs
Conclusions and clinical relevanceVeterinary students early in their training assigned pain scores to dogs that differed from scores assigned by experienced anesthesiologists. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - April 29, 2015 Category: Veterinary Research Authors: Michele Barletta, Courtni N Young, Jane E Quandt, Erik H Hofmeister Tags: Research Paper Source Type: research

Effects of acepromazine–morphine and acepromazine–methadone premedication on the minimum alveolar concentration of isoflurane in dogs
Conclusions and clinical relevanceThe percentage reduction of the ISOMAC in ACPMET was approximately twice that in ACPMOR. Premedication with acepromazine–morphine or acepromazine–methadone increased the incidence of bradycardia. Hypotension was observed in most dogs during isoflurane anesthesia regardless of premedication. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - April 17, 2015 Category: Veterinary Research Authors: Eduardo R Monteiro, Karina Coelho, Thais F Bressan, Clarissa R Simões, Betânia S Monteiro Tags: Research Paper Source Type: research

Corrigenda
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - April 17, 2015 Category: Veterinary Research Tags: Corrigendum Source Type: research

Corrigendum
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - April 17, 2015 Category: Veterinary Research Tags: Corrigendum Source Type: research