Testicular Functions and Clinical Characterization of Patients with Gender Dysphoria (GD) Undergoing Sex Reassignment Surgery (SRS)
ConclusionOnly patients that did not discontinue hormonal treatment showed feminized blood levels on the day of SRS. The ones who stopped re‐virilized quickly. Interestingly, testicular histology was highly heterogeneous irrespective of the treatment strategy, a phenomenon that requires further investigation. Schneider F, Neuhaus N, Wistuba J, Zitzmann M, Heß J, Mahler D, van Ahlen H, Schlatt S, and Kliesch S. Testicular functions and clinical characterization of patients with gender dysphoria (GD) undergoing sex reassignment surgery (SRS). J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 12, 2015 Category: Sexual Medicine Authors: Florian Schneider, Nina Neuhaus, Joachim Wistuba, Michael Zitzmann, Jochen Heß, Dorothee Mahler, Hermann Ahlen, Stefan Schlatt, Sabine Kliesch Tags: Original Research Source Type: research

Testosterone Concentrations and Cardiovascular Autonomic Neuropathy in Men with Type 1 Diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC)
ConclusionsTestosterone levels are not associated with CAN among men with type 1 diabetes. Although testosterone is associated with a higher Valsalva ratio, a more favorable indicator, the clinical significance of this association is not known. Kim C, Pop‐Busui R, Braffett B, Cleary PA, Bebu I, Wessells H, Orchard T, and Sarma AV, for the DCCT/E.D.I.C. Research Group. Testosterone concentrations and cardiovascular autonomic neuropathy in men with type 1 diabetes in the Epidemiology of Diabetes Interventions and Complications Study (EDIC). J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 12, 2015 Category: Sexual Medicine Authors: Catherine Kim, Rodica Pop‐Busui, Barbara Braffett, Patricia A. Cleary, Ionut Bebu, Hunter Wessells, Trevor Orchard, Aruna V. Sarma, Tags: Original Research Source Type: research

Erectile Dysfunction and Mortality in a National Prospective Cohort Study
ConclusionsED is associated with increased premature mortality risk. The present findings have major public health and clinical implications in that ED is a strong indicator of premature mortality. Therefore, patients with ED should be screened and possibly treated for complications that may increase the risk of premature death. Loprinzi PD and Nooe A. Erectile dysfunction and mortality in a national prospective cohort study. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 12, 2015 Category: Sexual Medicine Authors: Paul D. Loprinzi, Allison Nooe Tags: Brief Communication Source Type: research

Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta ‐Analysis
The Journal of Sexual Medicine,Volume 12, Issue 12, Page 2291-2300, December 2015. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Source Type: research

Editorial Comment on “The Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta‐Analysis”
The Journal of Sexual Medicine,Volume 12, Issue 12, Page 2301-2301, December 2015. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Source Type: research

Sildenafil Increases the p50 and Shifts the Oxygen –Hemoglobin Dissociation Curve to the Right
The Journal of Sexual Medicine,Volume 12, Issue 12, Page 2229-2232, December 2015. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Source Type: research

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The Journal of Sexual Medicine,Volume 12, Issue 12, Page 2291-2300, December 2015. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Source Type: research

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The Journal of Sexual Medicine,Volume 12, Issue 12, Page 2229-2232, December 2015. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Source Type: research

Correction of Retrograde Ejaculation in Patients with Diabetes Mellitus Using Endourethral Collagen Injection: Preliminary Results
ConclusionCorrection of RE in DM1 patients could be achieved with endourethral injection of collagen type 2. Kurbatov D, Russo GI, Galstyan GR, Rozhivanov R, Lepetukhin A, Dubsky S, Shwartz YG, Cimino S, Morgia G, Sansalone S. Correction of retrograde ejaculation in patients with diabetes mellitus using endourethral collagen injection: Preliminary results. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Dmitry Kurbatov, Giorgio Ivan Russo, G.R. Galstyan, Roman Rozhivanov, Alexander Lepetukhin, Sergey Dubsky, Y.G. Shwartz, Sebastiano Cimino, Giuseppe Morgia, Salvatore Sansalone Tags: Brief Communication Source Type: research

Partial Treatment Requests and Underlying Motives of Applicants for Gender Affirming Interventions
ConclusionIt becomes clear that partial treatment is requested by a substantial number of applicants. This emphasizes the need for gender identity clinics to provide information about the medical possibilities and limitations, and careful introduction and evaluation of non‐standard treatment options. Beek TF, Kreukels BPC, Cohen‐Kettenis PT, and Steensma TD. Partial treatment requests and underlying motives of applicants for gender affirming interventions. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Titia F. Beek, Baudewijntje P.C. Kreukels, Peggy T. Cohen‐Kettenis, Thomas D. Steensma Tags: Brief Report Source Type: research

Psychological Support, Puberty Suppression, and Psychosocial Functioning in Adolescents with Gender Dysphoria
ConclusionPsychological support and puberty suppression were both associated with an improved global psychosocial functioning in GD adolescents. Both these interventions may be considered effective in the clinical management of psychosocial functioning difficulties in GD adolescents. Costa R, Dunsford M, Skagerberg E, Holt V, Carmichael P, Colizzi M. Psychological support, puberty suppression, and psychosocial functioning in adolescents with gender dysphoria. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Rosalia Costa, Michael Dunsford, Elin Skagerberg, Victoria Holt, Polly Carmichael, Marco Colizzi Tags: Original Research Source Type: research

Effects of Aging and Cardiovascular Disease Risk Factors on the Expression of Sirtuins in the Human Corpus Cavernosum
ConclusionsOur results demonstrate for the first time expression of SIRT2–3 and SIRT5–7 in the human CC. Aged individuals with CVDRF presented an increase in SIRT7 protein levels and a decrease in mitochondrial SIRT3. This finding suggests that CVDRF induces the loss of antioxidant defense mechanisms leading to endothelial injury. Freitas M, Rodrigues AR, Tomada N, Fonseca J, Magalhães A, Gouveia AM, Neves D. Effects of aging and cardiovascular disease risk factors on the expression of sirtuins in the human corpus cavernosum. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Margarida Freitas, Adriana R. Rodrigues, Nuno Tomada, João Fonseca, Alexandre Magalhães, Alexandra M. Gouveia, Delminda Neves Tags: Original Research Source Type: research

Idiopathic Partial Thrombosis (IPT) of the Corpus Cavernosum: A Hypothesis‐Generating Case Series and Review of the Literature
ConclusionIPT is a condition that presents typically with perineal pain and swelling. Cycling is often seen as a provocative factor, while the presence of a fibrous web at the level of the crurocavernosal junction is the underlying disorder allowing for entrapment of blood in the crura. Conservative treatment provides a reasonably good outcome in most cases. For therapy resistant cases, surgery can be considered. Weyne E, Schillebeeckx C, Jamaer C, D'Hulst P, Bozzini G, Grunert R, d'Hondt F, Hoebeke P, Müller A, Van Renterghem K, Joniau S, Albersen M. Idiopathic partial thrombosis (IPT) of the corpus cavernosum; a hypothe...
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Emmanuel Weyne, Charlotte Schillebeeckx, Caroline Jamaer, Pieter D'Hulst, Giorgio Bozzini, Richard Grunert, Frederiek d'Hondt, Piet Hoebeke, Alexander Müller, Koenraad Van Renterghem, Steven Joniau, Maarten Albersen Tags: Original Research Source Type: research

Sildenafil Increases the p50 and Shifts the Oxygen–Hemoglobin Dissociation Curve to the Right
ConclusionSildenafil caused a dose‐dependent increase in the release of oxygen from the erythrocytes as shown by the increased p50 values and rightward shift of the oxygen–hemoglobin dissociation curve. Ellis SS and Pepple DJ. Sildenafil increases the p50 and shifts the oxygen–hemoglobin dissociation curve to the right. J Sex Med **;**:**–**. (Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Shantol Sastrice Ellis, Dagogo John Pepple Tags: Brief Communication Source Type: research

Editorial Comment on “The Interplay Between Premature Ejaculation and Erectile Dysfunction: A Systematic Review and Meta‐Analysis”
(Source: The Journal of Sexual Medicine)
Source: The Journal of Sexual Medicine - November 9, 2015 Category: Sexual Medicine Authors: Robert M. Coward Tags: Editorial Commentary Source Type: research