Comparison of Magnetic Resonance Imaging With Radionuclide Methods of Evaluating the Kidney
Nuclear medicine and MRI provide information about renal perfusion, function (glomerular filtration rate), and drainage. Some tracers that are used in nuclear medicine (technetium-diethylene triamine pentaacetic acid ([99mTc-DTPA] and 51chromium-EDTA) and some contrast media (CM) that are used for MRI (gadolinium-DTPA for instance) share the same pharmacokinetic properties, though, detection techniques are different (low-spatial resolution 2-dimensional projection with a good concentration-to-signal linearity for nuclear medicine and high-resolution 3-dimensional localization with nonlinear behavior for MRI). Thus, though ...
Source: Seminars in Nuclear Medicine - February 3, 2014 Category: Radiology Authors: Emmanuel Durand Source Type: research

Guest Editorial
The 15th International Symposium on Radionuclides in Nephrourology was held in Varese, Italy, from October 15-17. Varese, “the garden city” lays southward the Alpi mountain chain, in a region known as “the seven lakes land” named after the presence of many water bodies, the larger being the “Maggiore” lake. On its shores, crowning a small hill, a visitor can see the Borromeo castle, still property of the descendants of the family of the famous Cardinal, historical character of the literature masterpiece “I promessi sposi.” Some of the celebrities born in the surroundings are the writer, Piero Chiara; the li...
Source: Seminars in Nuclear Medicine - February 3, 2014 Category: Radiology Authors: Diego De Palma Source Type: research

Editorial
This issue of the Seminars in Nuclear Medicine is devoted to a subject that was one of the earliest applications of radionuclide methodology in clinical medicine. It represents a selection of articles from a meeting that has been held triennially continuously since 1971. Drs Jean Louis Funk-Brentano and M. Donald Blaufox decided to form a group that would pursue the subject of radionuclides in diseases of the kidneys and urinary tract after attending a meeting on the subject in Liege Belgium in 1967. The first of these meetings was held in 1971 in New York City and they have been held regularly at approximately 3-year inte...
Source: Seminars in Nuclear Medicine - February 3, 2014 Category: Radiology Authors: Leonard M. Freeman, M. Donald Blaufox Source Type: research

Perspectives in Molecular Imaging Through Translational Research, Human Medicine, and Veterinary Medicine
The concept of molecular imaging has taken off over the past 15 years to the point of the renaming of the Society of Nuclear Medicine (Society of Nuclear Medicine and Molecular Imaging) and Journals (European Journal of Nuclear Medicine and Molecular Imaging) and offering of medical fellowships specific to this area of study. Molecular imaging has always been at the core of functional imaging related to nuclear medicine. Even before the phrase molecular imaging came into vogue, radionuclides and radiopharmaceuticals were developed that targeted select physiological processes, proteins, receptor analogs, antibody-antigen in...
Source: Seminars in Nuclear Medicine - December 6, 2013 Category: Radiology Authors: Clifford R. Berry, Predeep Garg Source Type: research

Small-Animal Research Imaging Devices
The scientific study of living animals may be dated to Aristotle’s original dissections, but modern animal studies are perhaps a century in the making, and advanced animal imaging has emerged only during the past few decades. In vivo imaging now occupies a growing role in the scientific research paradigm. Imaging of small animals has been particularly useful to help understand human molecular biology and pathophysiology using rodents, especially using genetically engineered mice (GEM) with spontaneous diseases that closely mimic human diseases. Specific examples of GEM models of veterinary diseases exist, but in general,...
Source: Seminars in Nuclear Medicine - December 6, 2013 Category: Radiology Authors: Eugene J. Fine, Lawrence Herbst, Linda A. Jelicks, Wade Koba, Daniel Theele Source Type: research