Withdrawal of plasma estradiol is associated with increased anxiety reported by women in the first 12 hours after delivery
Transient mood changes, also known as postpartum blues, occur in 15 to 85% of women in the immediate puerperium (Henshaw, 2003) and are usually described as predictors of postpartum depression (DPP) (Reck et al., 2009). DPP is a severe condition affecting around 10 to 22% of the mothers (Gaynes et al., 2005). In recent reviews investigating predictors of postpartum depression, besides the role of postpartum blues and environmental stressors, hormonal changes were addressed as possible important biomarkers for this period (Garcia-Leal et al., 2017; Guintivano et al., 2018). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - November 2, 2018 Category: Psychiatry Authors: Marcos Gon çalves de Rezende, Cybele Garcia-Leal, Marcos Felipe Silva de Sá, Ricardo de Carvalho Cavalli, Cristina Marta Del-Ben Tags: Short Communication Source Type: research
Low vagal tone in two rat models of psychopathology involving high or low corticosterone stress responses
One of the current challenges in mental health research is the identification of risk factors and mechanisms related to individual vulnerability to develop psychopathologies (Weger and Sandi, 2018). Given the well-known impact of stress in triggering and exacerbating psychopathologies (de Kloet et al., 2016; McEwen et al., 2012), a great deal of research is concentrating on understanding the role of the major physiological stress systems [i.e., the autonomic nervous system (ANS) and the hypothalamic-pituitary-adrenocortical (HPA) axis] in this context (Carnevali et al., 2018; de Kloet et al., 2005; Pruessner et al., 1997; ...
Source: Psychoneuroendocrinology - November 2, 2018 Category: Psychiatry Authors: Damien Huzard, Sriparna Ghosal, Jocelyn Grosse, Luca Carnevali, Andrea Sgoifo, Carmen Sandi Source Type: research
Cross-sectional relationship between kynurenine pathway metabolites and cognitive function in major depressive disorder
Major depressive disorder (MDD) is one of the most prevalent and disabling psychiatric illness, with a high lifetime prevalence ranging from 10-15% (Kessler et al., 2005, 2013a). Cognitive dysfunction is a core diagnostic feature of MDD and is likely to cause considerable interference and functional impairment in patients' daily life function (Mcintyre et al., 2013), but effective alleviation of the cognitive deficits is difficult to achieve with current antidepressant therapies (Amado-Boccara et al., 1995). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - November 2, 2018 Category: Psychiatry Authors: Yanling Zhou, Wei Zheng, Weijian Liu, Chengyu Wang, Yanni Zhan, Hanqiu Li, Lijian Chen, Yuping Ning Source Type: research
Poor night ’s sleep predicts following day’s salivary alpha-amylase under high but not low stress
Poor sleep predicts next day ’s salivary alpha-amylase profile under stressThe salivary alpha-amylase profile is unrelated to following night’s sleepDiurnal salivary alpha-amylase profile is not sensitive to everyday occurring sleep variationsSalivary alpha-amylase profiles indicate autonomic nervous system dysregulation (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 29, 2018 Category: Psychiatry Authors: Kristina Klaus, Johanna M. Doerr, Jana Strahler, Nadine Skoluda, Alexandra Linnemann, Urs M. Nater Source Type: research
Memories of and influenced by the Trier Social Stress Test
Stress has obtained a rather bad reputation nowadays. It is often related to impaired cognitive performance and when occurring chronically it is commonly associated with physical and mental health problems. However, research has illustrated that the impact of stress on cognitive functions such as learning and memory are far more complex than initially assumed. Stress may enhance or impair memory depending on several key modulators and mediators. Both quantitative and qualitative shifts take place (Schwabe& Wolf, 2013). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 29, 2018 Category: Psychiatry Authors: Oliver T. Wolf Source Type: research
Hpa axis responses to psychological challenge linking stress and disease: what do we know on sources of intra- and interindividual variability?
Chronic stress is a major risk factor for several disorders, including highly prevalent diseases such as depression, anxiety disorders, cardiovascular diseases, and the metabolic syndrome (see 3.8 and 3.9). Since the finding of a disinhibited hypothalamic-pituitary-adrenal (HPA) axis in depressed patients (Carroll et al., 1980), it was assumed that alterations in the activity of this system may be a close correlate of stress-related pathology. The HPA axis is a core component of the neuroendocrine stress response. (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 29, 2018 Category: Psychiatry Authors: Sandra Z änkert, Silja Bellingrath, Stefan Wüst, Brigitte M. Kudielka Source Type: research
Women's fertility cues affect cooperative behavior: Evidence for the role of the human putative chemosignal estratetraenol
Human body odors have been shown to convey social signals of many kinds. In the animal kingdom, many mammalian species use odorous cues to communicate periods of reproduction readiness among females. Specifically, female body odor and other body secretions take on an attractive character around the ovulation period (Doty, 1986). In rodents for example, females' body odors are known to stimulate males' reproductive systems, causing an increase in males' testosterone levels (Brown& Macdonald, 1985). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 29, 2018 Category: Psychiatry Authors: Chen Oren, Simone G. Shamay-Tsoory Source Type: research
Methylation of the glucocorticoid receptor gene associated with depression in patients with acute coronary syndrome
Because acute coronary syndrome (ACS) is a leading cause of death, increased effort has been made toward improving its treatment outcomes and prognosis (Benjamin et al., 2018). Depression is a common comorbidity in ACS patients and is associated with poor prognoses with increased morbidity and mortality (Lichtman et al., 2014). These phenomena may be due to common biological mechanisms shared by ACS and depression. Because depression can be treated, a clearer understanding of the pathophysiology of depression in ACS patients could improve its prognosis. (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 29, 2018 Category: Psychiatry Authors: Hee-Ju Kang, Kyung-Yeol Bae, Sung-Wan Kim, Il-Seon Shin, Hye-Ran Kim, Myung-Geun Shin, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong, Jin-Sang Yoon, Jae-Min Kim Source Type: research
Assay Validation of Hair Androgens Across the Menstrual Cycle
Noninvasive measurement of androgens like testosterone and dehydroepiandrosterone (DHEA) in salivary samples has been widely used as an index of hypothalamic-pituitary-gonadal (HPG) axis responses to stress and daily experiences (Kirschbaum& Hellhammer, 1994; Meyer et al., 2014; Karlamangla et al., 2013) and applied to multiple professional fields such as human development, psychobiology and mental health (Adam, 2006; Knorr et al., 2010; Shirtcliff et al., 2009). The popularity of salivary biomarkers research is largely due to its feasibility, noninvasive ease of sampling, point-of-care collection and repeated sampling (Sh...
Source: Psychoneuroendocrinology - October 28, 2018 Category: Psychiatry Authors: Wen Wang, Shannin N. Moody, Jeff Kiesner, Anna T. Appiani, Olivia C. Robertson, Elizabeth A. Shirtcliff Source Type: research
Altered Cellular Immune Reactivity in Traumatized Women with and without Major Depressive Disorder
Alterations of the hypothalamic-pituitary-adrenal (HPA) axis such as altered glucocorticoid receptor sensitivity and increased immune reactivity might contribute to the pathogenesis of major depressive disorder (MDD) (Pariante, 2017). Exposure to adverse childhood experiences (ACE) enhances the risk to develop MDD later in life and is itself associated with changes in HPA axis function (Mandelli et al., 2015; Anacker et al., 2014). Indeed, a growing body of evidence suggests a close interplay among ACE, inflammation and altered HPA axis signaling in the pathogenesis of later life mental disorders (Nusslock and Miller, 2016...
Source: Psychoneuroendocrinology - October 28, 2018 Category: Psychiatry Authors: Julian Hellmann-Regen, Carsten Spitzer, Linn K. Kuehl, Katharina Schultebraucks, Christian Otte, Katja Wingenfeld Tags: Short Communication Source Type: research
Human chemosignals modulate emotional perception of biological motion in a sex-specific manner
Pheromones, secreted to the outside by an individual and received by a second individual of the same species, are ubiquitously used in the animal kingdom and mediate a wide range of social interactions (Karlson and Luscher, 1959; Wyatt, 2003). A well-studied class of pheromones is called sex pheromones, which regulate behaviors related to mate choice and reproduction. Their influence on the recipients take many forms, from priming the reproductive system (Keller-Costa et al., 2014), inducing preference, searching behavior, and the adoption of a mating stance in the opposite sex (Dorries et al., 1997; Li et al., 2002), to f...
Source: Psychoneuroendocrinology - October 27, 2018 Category: Psychiatry Authors: Yuting Ye, Yuan Zhuang, Monique A.M. Smeets, Wen Zhou Source Type: research
Effects of androsterone on the protective action of various antiepileptic drugs against maximal electroshock-induced seizures in mice
There are clinically important reciprocal interactions between androgens and the brain (Pack et al., 2011; Taub øll et al., 2015). Androgens can affect functions of the central nervous system (CNS) and play an important role in the pathophysiology of various neural disorders, including epilepsy (Verrotti et al., 2007, Reddy, 2013; Taubøll et al., 2015) while epilepsy and/or antiepileptic drugs can alter and rogen levels to promote the development of reproductive hormonal disorders (Herzog and Fowler, 2005; Røste et al., 2005). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 27, 2018 Category: Psychiatry Authors: Piotr Tutka, Katarzyna Mr óz, Tomasz Mróz, Grzegorz Buszewicz, David Aebisher, Dorota Bartusik-Aebisher, Patrycjusz Kołodziejczyk, Jarogniew J. Łuszczki Source Type: research
Salivary cortisone, as a biomarker for psychosocial stress, is associated with state anxiety and heart rate
An adaptive response to a stressor (i.e., a demand or threat) comprises activation in the central nervous system, the autonomic nervous system (ANS), and the endocrine system (Chrousos and Gold, 1992). The brain orchestrates the stress response and is central for the adaptation to current and future stressors (Ulrich-Lai and Herman, 2009). ANS stimulation is marked by a rapid increase of heart rate (Allen et al., 2014), the release of plasma catecholamines and salivary alpha-amylase (Granger et al., 2007; Rohleder and Nater, 2009). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 27, 2018 Category: Psychiatry Authors: Yoon Ju Bae, Janis Reinelt, Jeffrey Netto, Marie Uhlig, Anja Willenberg, Uta Ceglarek, Arno Villringer, Joachim Thiery, Michael Gaebler, Juergen Kratzsch Source Type: research
Salivary Uric Acid: Associations with Resting and Reactive Blood Pressure Response To Social Evaluative Stress in Healthy African Americans
In the United States, cardiovascular disease (CVD) disproportionately burdens African Americans (Association A.H., 2013). In addition to socioeconomic variables such as education and poverty and decreased access to preventive care, psychosocial variables, such as discrimination, are viewed as key determinants of CVD disparities (Adler, 2013; Ladwig et al., 2014). One particularly important precursor to CVD and disparity is psychobiological stress (Dimsdale, 2008). In tandem, African Americans have higher rates of many stress-related CVD risk factors (Blankstein et al., 2011; Flegal et al., 2010). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 26, 2018 Category: Psychiatry Authors: Jacqueline Woerner, Todd Lucas, Jennifer Pierce, Jenna L. Riis, Douglas A. Granger Source Type: research
Hypothalamic-pituitary-adrenal axis feedback sensitivity in different states of back pain
The transition from acute to chronic pain has been associated with a number of peripheral and central physiological, psychological and psychosocial predictors, among them prominently also stress experience and stress reactivity (e.g., Flor, 2017; Vachon-Presseau, 2018). The activation of the hypothalamic-pituitary-adrenal (HPA) axis plays an important mediating role in the relationship between stress and pain (e.g., McEwen and Kalia, 2010). In acute pain, higher baseline cortisol levels are associated with lower pain reports (Al ’Absi et al., 2002). (Source: Psychoneuroendocrinology)
Source: Psychoneuroendocrinology - October 26, 2018 Category: Psychiatry Authors: Frauke Nees, Martin L öffler, Katrin Usai, Herta Flor Source Type: research
