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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 5, 2017 Category: Biochemistry Source Type: research

Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants
Conclusion and clinical relevanceMVs from MSCs conduct aerobic metabolism similarly to exosomes from the same cells, with interesting differences related to their biogenesis and function. The clinical relevance of the study lays in the perspective to utilize MVs as promising sensor of the inflammatory and metabolic state of the preterm newborn, to help in preventing the complications of prematurity. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 5, 2017 Category: Biochemistry Authors: Maurizio Bruschi, Laura Santucci, Silvia Ravera, Martina Bartolucci, Andrea Petretto, Daniela Calzia, Gian Marco Ghiggeri, Luca A. Ramenghi, Giovanni Candiano, Isabella Panfoli Tags: RESEARCH ARTICLE Source Type: research

A Lipidomics Approach to Identifying Key Lipid Species Involved in VEGF ‐Inhibitor Mediated Attenuation of Bleomycin‐Induced Pulmonary Fibrosis
Conclusion and clinical relevance: Dysregulated lipids identified in this study hold the potential of being future biomarkers for IPF.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 1, 2017 Category: Biochemistry Authors: Yogesh M. Kulkarni, Sucharita Dutta, Anand Krishnan V. Iyer, Clayton A. Wright, Vani Ramesh, Vivek Kaushik, Oliver John Semmes, Neelam Azad Tags: RESEARCH ARTICLE Source Type: research

The impact of the glomerular filtration rate on the human plasma proteome
Conclusions and clinical relevance: Overall, this study represents the most extensive characterization of the plasma proteome and its relation to GFR to date, and suggests the diagnostic and prognostic value of proteomics for CKD across all stages. This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 1, 2017 Category: Biochemistry Authors: Anders Christensson, Jessica A. Ash, Robert K. DeLisle, Fraser W. Gaspar, Rachel Ostroff, Anders Grubb, Veronica Lindstr öm, Laila Bruun, Steve A. Williams Tags: RESEARCH ARTICLE Source Type: research

Chemotherapy Immunophenoprofiles in Non –small‐cell Lung Cancer by Personalized Membrane Proteomics
Conclusion and Clinical Relevance:Without the additional isolation of specific immune cell populations, our study demonstrated that PEM–CIS chemotherapy altered patients’ immune system in terms of neutrophils, T cells, and antigen presentation pathways. This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 1, 2017 Category: Biochemistry Authors: Denise Utami Putri, Po ‐Hao Feng, Yuu‐Hueih Hsu, Kang‐Yun Lee, Feng‐Wen Jiang, Lu‐Wei Kuo, Yu‐Ju Chen, Chia‐Li Han Tags: RESEARCH ARTICLE Source Type: research

iTRAQ based proteomic analysis reveals protein profile in plasma from children with autism
Conclusion: These above described proteins are found involved in different pathways that have previously been linked to the pathophysiology of autism spectrum disorders (ASDs). The results strongly support that focal adhesions, acting cytoskeleton, cell adhesion, motility and migration, synaptogenesis, and complement system are involved in the pathogenesis of autism, and highlight the important role of platelet function in the pathophysiology of autism.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 1, 2017 Category: Biochemistry Authors: Liming Shen, Kaoyuan Zhang, Chengyun Feng, Youjiao Chen, Shuiming Li, Javed Iqbal, Liping Liao, Yuxi Zhao, Jian Zhai Tags: RESEARCH ARTICLE Source Type: research

Development and validation of mass spectrometry ‐based targeted analysis for amyloid proteins
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 1, 2017 Category: Biochemistry Authors: Jisook Park, Ga Yeon Lee, Jin ‐Oh Choi, Eun‐Seok Jeon, Kihyun Kim, Jung‐Sun Kim, Soo‐Youn Lee Tags: Technical Brief Source Type: research

A Proteogenomic Analysis of Haptoglobin in Malaria
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 23, 2017 Category: Biochemistry Authors: GauriAwasthi , SuchiTyagi , VipinKumar , Sandip KumarPatel , DharmendarRojh , VijethSakrappanavar , Sanjay KumarKochar , ArunansuTalukdar , BiausSamanta , AparupDas , SanjeevaSrivastava , SwatiPatankar Source Type: research

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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 23, 2017 Category: Biochemistry Source Type: research

A Proteogenomic Analysis of Haptoglobin in Malaria
Conclusion and clinical relevanceThis proteo‐genomic study focuses on the correlation of the Hp protein and gene with malaria, thus highlighting the pivotal role of this acute phase immune gene in malaria pathogenesis. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 23, 2017 Category: Biochemistry Authors: Gauri Awasthi, Suchi Tyagi, Vipin Kumar, Sandip Kumar Patel, Dharmendar Rojh, Vijeth Sakrappanavar, Sanjay Kumar Kochar, Arunansu Talukdar, Biaus Samanta, Aparup Das, Sanjeeva Srivastava, Swati Patankar Tags: RESEARCH ARTICLE Source Type: research

Ubiquitin ‐Conjugating Enzyme E2 L3 is Downregulated by the Chikungunya Virus nsP2 Protease
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 16, 2017 Category: Biochemistry Authors: SuwipaRamphan , SarawutKhongwichit , ChontichaSaisawang , DuangnapaKovanich , Albert J.Ketterman , SukathidaUbol , PrasertAuewarakul , SittirukRoytrakul , Duncan R.Smith , AtichatKuadkitkan Source Type: research