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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 27, 2018 Category: Biochemistry Source Type: research
The impact of pre ‐analytical conditions on human serum peptidome profiling
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 24, 2018 Category: Biochemistry Authors: Andrea Padoan Tags: COMMENTARY Source Type: research
Cell ‐Free DNA Blood Collection Tubes are Appropriate for Clinical Proteomics: a Demonstration in Colorectal Cancer
Conclusions: Optimized BCT are appropriate for low‐abundant plasma protein analysis and can be used with confidence for clinical proteomics.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 24, 2018 Category: Biochemistry Authors: Juhura G. Almazi, Peter Pockney, Craig Gedye, Nathan D. Smith, Hubert Hondermarck, Nicole M. Verrills, Matthew D. Dun Tags: Technical Brief Source Type: research
Label ‐Free Quantitative Proteomic Screening of Candidate Plasma Biomarkers for the Prognosis of Breast Cancer with Different Lymph Node Statuses
PROTEOMICS – Clinical Applications,Volume 12, Issue 3, May 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Authors: LingChen
,
WeiboZhao
,
JingHe
,
LiqiLi
,
DongMeng
,
DongyanCai
,
JinjinYu
,
DaozhenChen
,
YiboWu
,
TaoZhou Source Type: research
Establishment of a CRISPR/Cas9 ‐Mediated Cysltr1 Knockout Mouse Model and iTRAQ‐Based Proteomic Analysis
PROTEOMICS – Clinical Applications,Volume 12, Issue 3, May 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Authors: JunjieMao
,
XiaojunHu
,
PengfeiPang
,
BinZhou
,
YaqinZhang
,
DanLi
,
HongShan Source Type: research
Label ‐Free Quantitative Proteomic Screening of Candidate Plasma Biomarkers for the Prognosis of Breast Cancer with Different Lymph Node Statuses
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Source Type: research
Establishment of a CRISPR/Cas9 ‐Mediated Cysltr1 Knockout Mouse Model and iTRAQ‐Based Proteomic Analysis
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Source Type: research
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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Source Type: research
Establishment of a CRISPR/Cas9 ‐Mediated Cysltr1 Knockout Mouse Model and iTRAQ‐Based Proteomic Analysis
Conclusions and Clinical RelevanceThis study not only provides a comprehensive dataset on overall protein changes in Cysltr1 KO mice lung tissues, but also sheds light on interpreting the description of lower vascular permeability in Cysltr1 KO mice. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 14, 2018 Category: Biochemistry Authors: Junjie Mao, Xiaojun Hu, Pengfei Pang, Bin Zhou, Yaqin Zhang, Dan Li, Hong Shan Tags: RESEARCH ARTICLE Source Type: research
Mass Spectrometry Analyses of Multicellular Tumor Spheroids
PROTEOMICS – Clinical Applications,Volume 12, Issue 3, May 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 9, 2018 Category: Biochemistry Authors: MitchellAcland
,
ParulMittal
,
Noor A.Lokman
,
ManuelaKlingler ‐Hoffmann
,
Martin K.Oehler
,
PeterHoffmann Source Type: research
Mass Spectrometry Analyses of Multicellular Tumor Spheroids
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 9, 2018 Category: Biochemistry Source Type: research
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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - February 9, 2018 Category: Biochemistry Source Type: research
Mass Spectrometry Analyses of Multicellular Tumor Spheroids
Abstract
Multicellular tumor spheroids (MCTS) are a powerful biological in vitro model, which closely mimics the 3D structure of primary avascularized tumors. Mass spectrometry (MS) has established itself as a powerful analytical tool, not only to better understand and describe the complex structure of MCTS, but also to monitor their response to cancer therapeutics. The first part of this review focuses on traditional mass spectrometry approaches with an emphasis on elucidating the molecular characteristics of these structures. Then the mass spectrometry imaging (MSI) approaches used to obtain spatially defined information...
Source: Proteomics. Clinical Applications - February 9, 2018 Category: Biochemistry Authors: Mitchell Acland, Parul Mittal, Noor A. Lokman, Manuela Klingler ‐Hoffmann, Martin K. Oehler, Peter Hoffmann Tags: REVIEW Source Type: research
