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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 16, 2017 Category: Biochemistry Source Type: research
Proteomics of Diabetes, Obesity, and Related Disorders
(Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 16, 2017 Category: Biochemistry Authors: Robert Moulder, Domitille Schvartz, David R. Goodlett, Lo ïc Dayon Tags: Editorial Source Type: research
Metabolic Signature of Microvescicles from Umbilical Cord Mesenchimal Stem Cells of Preterm and Term Infants
Conclusions and clinical relevanceMicrovesicles from mesenchymal stem cells conduct aerobic metabolism similarly to exosomes from the same cells, with interesting differences related to their biogenesis and function. The clinical relevance of the study lays in the perspective to utilize Microvesicles as promising sensor of the inflammatory and metabolic state of the preterm newborn, to help in preventing the complications of prematurity.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - November 16, 2017 Category: Biochemistry Authors: Maurizio Bruschi, Laura Santucci, Silvia Ravera, Martina Bartolucci, Andrea Petretto, Daniela Calzia, Gianmarco Ghiggeri, Luca A. Ramenghi, Giovanni Candiano, Isabella Panfoli Tags: Research Article Source Type: research
PepSweetener: A Web ‐Based Tool to Support Manual Annotation of Intact Glycopeptide MS Spectra
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 30, 2017 Category: Biochemistry Authors: Marcin JakubDomagalski
,
DavideAlocci
,
AndreiaAlmeida
,
DanielKolarich
,
Fr édériqueLisacek Source Type: research
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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 30, 2017 Category: Biochemistry Source Type: research
Intersection of Proteomics and Genomics to “Solve the Unsolved” in Rare Disorders such as Neurodegenerative and Neuromuscular Diseases
PROTEOMICS – Clinical Applications,Volume 12, Issue 2, March 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 23, 2017 Category: Biochemistry Source Type: research
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PROTEOMICS – Clinical Applications,Volume 12, Issue 2, March 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 23, 2017 Category: Biochemistry Source Type: research
Intersection of Proteomics and Genomics to “Solve the Unsolved” in Rare Disorders such as Neurodegenerative and Neuromuscular Diseases
Abstract
Despite recent rapid advances in sequencing technologies, a significant proportion of patients with rare genetic disorders do not receive a genetic diagnosis after exhaustive testing, and even fewer have a potential therapeutic target identified. Taking rare neuromuscular and neurodegenerative disorders as a paradigm that can be extended to other rare Mendelian disorders, this viewpoint explores the opportunities that are brought about by the integration of genomics and proteomics, as well as the limitations and remaining challenges of this newly emerging field of proteogenomics. The relevance of combining proteom...
Source: Proteomics. Clinical Applications - October 23, 2017 Category: Biochemistry Authors: Andreas Roos, Rachel Thompson, Rita Horvath, Hanns Lochm üller, Albert Sickmann Tags: VIEWPOINT Source Type: research
A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimer's Disease
Conclusion and clinical relevancePRM‐MS of protein panels is a valuable tool to evaluate biomarker candidates for neurodegenerative disorders.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 13, 2017 Category: Biochemistry Authors: Gunnar Brinkmalm, Simon Sj ödin, Anja Hviid Simonsen, Steen Gregers Hasselbalch, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow Tags: RESEARCH ARTICLE Source Type: research
Clinical Proteomics for Precision Medicine: The Bladder Cancer Case
PROTEOMICS – Clinical Applications,Volume 12, Issue 2, March 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 5, 2017 Category: Biochemistry Source Type: research
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PROTEOMICS – Clinical Applications,Volume 12, Issue 2, March 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 5, 2017 Category: Biochemistry Source Type: research
Ubiquitin ‐Conjugating Enzyme E2 L3 is Downregulated by the Chikungunya Virus nsP2 Protease
ConclusionThese results suggest that UBE2L3 is a cellular target of the CHIKV nsP2 protease, and this possibly mediates the pathogenesis of chikungunya fever.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 4, 2017 Category: Biochemistry Authors: Suwipa Ramphan, Sarawut Khongwichit, Chonticha Saisawang, Duangnapa Kovanich, Albert J. Ketterman, Sukathida Ubol, Prasert Auewarakul, Sittiruk Roytrakul, Duncan R. Smith, Atichat Kuadkitkan Tags: RESEARCH ARTICLE Source Type: research
PepSweetener: A Web ‐Based Tool to Support Manual Annotation of Intact Glycopeptide MS Spectra
Conclusions and clinical relevance: PepSweetener efficiently allows the selection of the most probable intact glycopeptide mass matches and speeds up the verification process. It was validated on serum protein samples and immunoglobulins. The tool is publicly hosted on ExPASy, the SIB Swiss Institute of Bioinformatics resource portal (http://glycoproteome.expasy.org/pepsweetener/app/).This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - October 3, 2017 Category: Biochemistry Authors: Marcin Jakub Domagalski, Davide Alocci, Andreia Almeida, Daniel Kolarich, Fr édérique Lisacek Tags: TECHNICAL BRIEF Source Type: research
Emerging Diagnostic and Therapeutic Potentials of Human Hair Proteomics
PROTEOMICS – Clinical Applications,Volume 12, Issue 2, March 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - September 27, 2017 Category: Biochemistry Source Type: research
