Chemotherapy Immunophenoprofiles in Non ‐Small‐Cell Lung Cancer by Personalized Membrane Proteomics
Conclusion and Clinical Relevance: Without the additional isolation of specific immune cell populations, our study demonstrated that PEM–CIS chemotherapy altered patients’ immune system in terms of neutrophils, T cells, and antigen presentation pathways. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 19, 2018 Category: Biochemistry Authors: Denise Utami Putri, Po ‐Hao Feng, Yuu‐Hueih Hsu, Kang‐Yun Lee, Feng‐Wen Jiang, Lu‐Wei Kuo, Yu‐Ju Chen, Chia‐Li Han Tags: RESEARCH ARTICLE Source Type: research
Assessment by Matrix ‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of the Effects of Preanalytical Variables on Serum Peptidome Profiles Following Long‐Term Sample Storage
Conclusions and clinical relevanceThese peaks can be used as sample quality markers to assess the effects of long‐term storage on serum peptidome profiles using MALDI‐TOF MS.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 19, 2018 Category: Biochemistry Authors: Sachio Tsuchida, Mamoru Satoh, Hiroshi Umemura, Kazuyuki Sogawa, Masaki Takiwaki, Takayuki Ishige, Yui Miyabayashi, Yuuya Iwasawa, Sohei Kobayashi, Minako Beppu, Motoi Nishimura, Yoshio Kodera, Kazuyuki Matsushita, Fumio Nomura Tags: RESEARCH ARTICLE Source Type: research
Variability Assessment of 90 Salivary Proteins in Intra ‐Day and Inter‐Day Samples from Healthy Donors by Multiple Reaction Monitoring‐Mass Spectrometry
Conclusions and clinical relevanceOur study elucidated the intra‐ and inter‐individual variability of 90 disease‐related proteins in saliva samples from healthy donors. The findings may facilitate the further development of salivary biomarkers for oral and systemic diseases.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 19, 2018 Category: Biochemistry Authors: Yung ‐Chin Hsiao, Lichieh Julie Chu, Yi‐Ting Chen, Lang‐Ming Chi, Kun‐Yi Chien, Wei‐Fan Chiang, Ya‐Ting Chang, Szu‐Fan Chen, Wei‐Shun Wang, Yao‐Ning Chuang, Shih‐Yu Lin, Chih‐Yen Chien, Kai‐Ping Chang, Yu‐Sun Chang, Jau‐Song Yu Tags: RESEARCH ARTICLE Source Type: research
iTRAQ ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism
PROTEOMICS – Clinical Applications,Volume 12, Issue 3, May 2018. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 18, 2018 Category: Biochemistry Authors: LimingShen
,
KaoyuanZhang
,
ChengyunFeng
,
YoujiaoChen
,
ShuimingLi
,
JavedIqbal
,
LipingLiao
,
YuxiZhao
,
JianZhai Source Type: research
iTRAQ ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 18, 2018 Category: Biochemistry Source Type: research
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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 18, 2018 Category: Biochemistry Source Type: research
iTRAQ ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism
ConclusionThese above described proteins are found involved in different pathways that have previously been linked to the pathophysiology of autism spectrum disorders (ASDs). The results strongly support that focal adhesions, acting cytoskeleton, cell adhesion, motility and migration, synaptogenesis, and complement system are involved in the pathogenesis of autism, and highlight the important role of platelet function in the pathophysiology of autism. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 18, 2018 Category: Biochemistry Authors: Liming Shen, Kaoyuan Zhang, Chengyun Feng, Youjiao Chen, Shuiming Li, Javed Iqbal, Liping Liao, Yuxi Zhao, Jian Zhai Tags: RESEARCH ARTICLE Source Type: research
Editorial board: Proteomics 1'18
(Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 17, 2018 Category: Biochemistry Tags: EDITORIAL BOARD Source Type: research
Back Cover: MALDI Imaging ‐Guided Microproteomic Analyses of Heterogeneous Breast Tumors—A Pilot Study
Matrix‐assisted laser desorption ionisation (MALDI)‐imaging coupled to laser microdissection (LMD)‐based microproteomics to study intratumor heterogeneity.
MALDI imaging dataset from breast cancer FFPE tissue sections were segmented to draw intratumor proteomic heterogeneity. Tissue regions containing 3500 cells from different molecular clusters were collected by LMD and processed for further microproteomic analyses. The combination of MALDI imaging with LMD‐based microproteomics will pave the way to in‐depth characterization of intratumor heterogeneity in pathology. This is reported by Deborah Alberts, Charles ...
Source: Proteomics. Clinical Applications - January 17, 2018 Category: Biochemistry Authors: Deborah Alberts, Charles Pottier, Nicolas Smargiasso, Dominique Baiwir, Gabriel Mazzucchelli, Philippe Delvenne, Mark Kriegsmann, Daniel Kazdal, Arne Warth, Edwin Pauw, R émi Longuespée Tags: BACK COVER Source Type: research
Front Cover: The differential plasma proteome of obese and overweight individuals undergoing a nutritional weight loss and maintenance intervention
In the pan‐European DiOGenes study; a cohort of nearly 500 overweight subjects underwent a low‐calorie meal replacement diet intervention, followed by a weight maintenance period. Plasma samples before and after the study were analysed using mass spectrometry and a differential proteome analysis was performed, also highlighting protein associations with clinical relevant variables such as BMI, HOMA, Matsuda, and fat mass. This is reported by Sergio Oller Moreno, Ornella Cominetti, Antonio Núñez Galindo, Irina Irincheeva, John Corthésy, Arne Astrup, Wim H.M. Saris, Jörg Hager, Martin Kussmann and Loïc Dayon, articl...
Source: Proteomics. Clinical Applications - January 17, 2018 Category: Biochemistry Authors: Sergio Oller Moreno, Ornella Cominetti, Antonio N úñez Galindo, Irina Irincheeva, John Corthésy, Arne Astrup, Wim H.M. Saris, Jörg Hager, Martin Kussmann, Loïc Dayon Tags: FRONT COVER Source Type: research
Malaria in India: The Need for New Targets for Diagnosis and Detection of Plasmodium vivax
PROTEOMICS – Clinical Applications, EarlyView. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 11, 2018 Category: Biochemistry Authors: SwatiPatankar
,
ShobhonaSharma
,
Pradipsinh K.Rathod
,
Manoj T.Duraisingh Source Type: research
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PROTEOMICS – Clinical Applications, Ahead of Print. (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 11, 2018 Category: Biochemistry Source Type: research
Sleeping sickness in the ‘omics era
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Natalia Tiberti, Jean ‐Charles Sanchez Tags: REVIEW Source Type: research
