iTRAQ ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism

ConclusionThese above described proteins are found involved in different pathways that have previously been linked to the pathophysiology of autism spectrum disorders (ASDs). The results strongly support that focal adhesions, acting cytoskeleton, cell adhesion, motility and migration, synaptogenesis, and complement system are involved in the pathogenesis of autism, and highlight the important role of platelet function in the pathophysiology of autism.

Source: Proteomics. Clinical Applications - January 18, 2018 Category: Biochemistry Authors: Liming Shen, Kaoyuan Zhang, Chengyun Feng, Youjiao Chen, Shuiming Li, Javed Iqbal, Liping Liao, Yuxi Zhao, Jian Zhai Tags: RESEARCH ARTICLE Source Type: research