Effects of let ‐7e on LPS‐Stimulated THP‐1 Cells Assessed by iTRAQ Proteomic Analysis
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Lian Gui, Qianqian Zhang, Yan Cai, Xiaohong Deng, Yingke Zhang, Cheukfai Li, Qi Guo, Xiaoshun He, Junqi Huang Tags: RESEARCH ARTICLE Source Type: research
‘One‐pot’ Sample Processing Method for Proteome‐wide Analysis of Microbial Cells and Spores
Conclusions and medical relevanceThis method can be employed for proteome‐wide analysis of non‐spore‐forming as well as spore‐forming pathogens. Analysis of spore protein profile will help to understand the sporulation and germination processes and to distinguish immunogenic protein markers.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Bhagyashree Nandakishor Swarge, Winfried Roseboom, Linli Zheng, Wishwas R. Abhyankar, Stanley Brul, Chris G. Koster, Leo J. Koning Tags: RESEARCH ARTICLE Source Type: research
Integrated Multi ‐Omic Analyses Support Distinguishing Secretory Carcinoma of the Breast from Basal‐Like Triple‐Negative Breast Cancer
Conclusion and clinical relevance: Our multi‐omic analyses provide evidence that SC harbours substantially different molecular genomic and proteomic landscapes compared with BL‐TNBC. These results provide an entire spectrum of in‐depth molecular landscapes to support the hypothesis that SC is distinct from BL‐TNBC.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Min ‐Sun Jin, Hyebin Lee, Jongmin Woo, Seongmin Choi, Mi Sol Do, Kwangsoo Kim, Min Ji Song, Youngsoo Kim, In Ae Park, Dohyun Han, Han Suk Ryu Tags: Dataset Brief Source Type: research
Differential metabolic pathway analysis of the proteomes of Leishmania donovani and Leptomonas seymouri
Conclusions and Clinical relevanceThe information provided about the metabolic pathways modulated when contrasting these two phenotypes may lead to the development of new strategies to block parasite differentiation within the host and to also circumvent the problem of drug resistance. This proteomic study also offers new grounds for the investigation of novel hypothetical proteins potentially playing a role in evolutionary biology the knowledge of which is essential for treatment of patients co‐infected with these two kinetoplastid parasites.This article is protected by copyright. All rights reserved (Source: Proteomics...
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Neeloo Singh, Renu Goel, Ekta Jain Tags: RESEARCH ARTICLE Source Type: research
Identification of SCARA5 as a potential biomarker for oral squamous cell carcinoma using MALDI TOF MS analysis
Conclusions and clinical relevanceScara5 has the potential to be considered as a serum biomarker in the early diagnosis of OSCC. The clinical relevance of the study lies in finding the biomarker by proteomics and subsequently validating it with clinical samples and cell lines.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Ying Liu, Yi ‐ran Tan, Wen‐wen Sun, Wu‐tong Ju, Yong Fu, Li‐zhen Wang, Jiang Li, Chen‐ping Zhang, Zhi‐yuan Zhang, Lai‐ping Zhong Tags: Research Article Source Type: research
Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine
Conclusions and Clinical Relevance: This is the first application of a LFQ‐PRM workflow to identify and validate ovarian cancer‐specific biomarkers in patient urine samples.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Jarrod J. Sandow, Adam Rainczuk, Giuseppe Infusini, Ming Makanji, Maree Bilandzic, Amy L. Wilson, Nicole Fairweather, Peter G. Stanton, Daniel Garama, Daniel Gough, Thomas W. Jobling, Andrew I. Webb, Andrew N. Stephens Tags: RESEARCH ARTICLE Source Type: research
The Glycoproteomics ‐mass Spectrometry for Studying Glycosylation in Cardiac Hypertrophy and Heart Failure
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Shuang Yang, Subroto Chatterjee, John Cipollo Tags: Review Source Type: research
Plasma Proteomic Signatures in Early Chronic Obstructive Pulmonary Disease
Conclusion and clinical releanceThese results indicate that specific proteomic signatures can be detected and useful in terms of treatment selection and in early COPD patients monitoring.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Angela Baralla, Alessandro G Fois, Elisabetta Sotgiu, Elisabetta Zinellu, Arduino A Mangoni, Salvatore Sotgia, Angelo Zinellu, Pietro Pirina, Ciriaco Carru Tags: RESEARCH ARTICLE Source Type: research
Identification of Host ‐Response in Cerebral Malaria Patients Using Quantitative Proteomic Analysis
Conclusions and clinical relevance: Our study signifies neuronal assault due to axonal injury, altered sodium and calcium ion channels, deregulated inflammation and demyelination as a part of host response to CM. Enhanced oxidative stress, repressed oxidative phosphorylation and demyelination of axons may contribute to the severity of the disease. Further validation of these results on a large cohort can provide leads in the development of neuroprotective therapies for CM.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Manish Kumar, Chakrakodi N. Varun, Gourav Dey, Raju Ravikumar, Anita Mahadevan, Susarla Krishna Shankar, T. S. Keshava Prasad Tags: RESEARCH ARTICLE Source Type: research
Label ‐Free Quantitative Proteomic Screening of Candidate Plasma Biomarkers for the Prognosis of Breast Cancer with Different Lymph Node Statuses
Conclusions and clinical relevanceThe present dataset provides a list of candidate biomarkers that could be used for early differentiation diagnosis and prognosis of breast cancer with lymph node metastasis.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Ling Chen, Weibo Zhao, Jing He, Liqi Li, Dong Meng, Dongyan Cai, Jinjin Yu, Daozhen Chen, Yibo Wu, Tao Zhou Tags: Dataset Brief Source Type: research
Establishment of a CRISPR/Cas9 ‐mediated Cysltr1 Knock Out Mouse Model and iTRAQ‐based Proteomic Analysis
Conclusions and Clinical RelevanceThis study not only provides a comprehensive dataset on overall protein changes in Cysltr1 KO mice lung tissues, but also shed light on interpreting the description of lower vascular permeability in Cysltr1 KO mice.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Junjie Mao, Xiaojun Hu, Pengfei Pang, Bin Zhou, Yaqin Zhang, Dan Li, Hong Shan Tags: RESEARCH ARTICLE Source Type: research
An MRM ‐Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung‐Cancer Pleural Effusions
Conclusion and clinical relevance: An MRM‐based CK assay for carcinoma studies can differentiate between the three lung‐cancer histological types using less‐invasive PE sampling providing potential therapy‐guiding information on patients that are inoperable.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Anna Perzanowska, Agnieszka Fatalska, Grzegorz Wojtas, Andrzej Lewandowicz, Agata Michalak, Grzegorz Krasowski, Christoph H. Borchers, Michal Dadlez, Dominik Domanski Tags: RESEARCH ARTICLE Source Type: research
Identification of p90 Ribosomal S6 Kinase 2 as a Novel Host Protein in HBx Augmenting HBV Replication by iTRAQ ‐based Quantitative Comparative Proteomics
Conclusion And Clinical Relevance: Based o n iTRAQ quantitative comparative proteomics, RSK2 was identified as a novel host protein that plays a role in HBx augmenting HBV replication.This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - January 1, 2018 Category: Biochemistry Authors: Li ‐Bo Yan, You‐Jia Yu, Qing‐Bo Zhang, Xiao‐Qiong Tang, Lang Bai, FeiJun Huang, Hong Tang Tags: RESEARCH ARTICLE Source Type: research
A Perspective on Proteomics of Infectious Diseases
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 28, 2017 Category: Biochemistry Authors: Apoorva Venkatesh, Concha Gil, Manuel Fuentes, Joshua LaBaer, Sanjeeva Srivastava Tags: Viewpoint Source Type: research
Understanding TGEV ‐ETEC Coinfection through the Lens of Proteomics: A Tale of Porcine Diarrhea
This article is protected by copyright. All rights reserved (Source: Proteomics. Clinical Applications)
Source: Proteomics. Clinical Applications - December 27, 2017 Category: Biochemistry Authors: Guillermo Arango Duque, Hamlet Adolfo Acevedo Ospina Tags: COMMENTARY Source Type: research
