Metabolic Signature of Microvesicles from Umbilical Cord Mesenchymal Stem Cells of Preterm and Term Infants

Conclusion and clinical relevanceMVs from MSCs conduct aerobic metabolism similarly to exosomes from the same cells, with interesting differences related to their biogenesis and function. The clinical relevance of the study lays in the perspective to utilize MVs as promising sensor of the inflammatory and metabolic state of the preterm newborn, to help in preventing the complications of prematurity.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fprca.201700082

Source: Proteomics. Clinical Applications - December 5, 2017 Category: Biochemistry Authors: Maurizio Bruschi, Laura Santucci, Silvia Ravera, Martina Bartolucci, Andrea Petretto, Daniela Calzia, Gian Marco Ghiggeri, Luca A. Ramenghi, Giovanni Candiano, Isabella Panfoli Tags: RESEARCH ARTICLE Source Type: research