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Introduction: Controversies in Hypertension
“Controversy should be welcomed, as it is only through controversy that science advances…”1,2 (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 31, 2016 Category: Cardiology Authors: Franz H. Messerli, Sripal Bangalore Tags: Editorial Source Type: research

Masthead
(Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 31, 2016 Category: Cardiology Source Type: research

Table of Contents
(Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 31, 2016 Category: Cardiology Source Type: research

List of recent issues
(Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 31, 2016 Category: Cardiology Source Type: research

Editorial Board
(Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 31, 2016 Category: Cardiology Source Type: research

Beta-Adrenergic Receptor Blockers in Hypertension: Alive and Well
βeta-Adrenergic receptor blockers (β-blockers) are an appropriate treatment for patients having systemic hypertension (HTN) who have concomitant ischemic heart disease (IHD), heart failure, obstructive cardiomyopathy, aortic dissection or certain cardiac arrhythmias. β-blockers can be used in com bination with other antiHTN drugs to achieve maximal blood pressure control. Labetalol can be used in HTN emergencies and urgencies. β-blockers may be useful in HTN patients having a hyperkinetic circulation (palpitations, tachycardia, HTN, and anxiety), migraine headache, and essential tremor. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 26, 2016 Category: Cardiology Authors: William H. Frishman Source Type: research

Renal Denervation for Resistant Hypertension
Renal denervation as a treatment for hypertension (HTN) has been shown to be effective as a surgical procedure. Over the past ten years, an endovascular approach to replicate the results of surgical splanchnicectomy has been investigated to replace this surgical procedure with a less invasive procedure with lower morbidity. Several devices and procedures have been developed, including a non-invasive strategy. We review the improvement of HTN in clinical trials of these devices as well as the shortcomings of these studies. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 23, 2016 Category: Cardiology Authors: John P. Reilly, Christopher J. White Source Type: research

Renin Angiotensin Aldosterone System Inhibitors In Hypertension: Is There Evidence For Benefit Independent Of Blood Pressure Reduction?
Abstract.The renin-angiotensin-aldosterone system (RAAS) plays a pivotal role in the pathogenesis of hypertension (HTN). Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are first line anti-HTN drug classes that are potent, effective and largely safe. Direct renin inhibitors (DRIs) have shown similar blood pressure (BP) reduction but more side effects. The efficacy of ACEIs and ARBs (for cardiovascular, cerebrovascular and renal protection) has been promoted to extend beyond what could be explained by BP reduction alone. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - October 20, 2016 Category: Cardiology Authors: Chirag Bavishi, Sripal Bangalore, Franz H. Messerli Source Type: research

Recurrent Pericarditis
Recurrent pericarditis is the most common and troublesome complication of pericarditis affecting 20 to 50% of patients. Its pathogenesis is often presumed to be immune-mediated, but additional investigations are needed to clarify the pathogenesis in order to develop etiology-oriented therapies. Imaging with Computed Tomography and especially Cardiac Magnetic Resonance holds promise to help in the identification of more difficult cases and improve their management.Refractory recurrent pericarditis with corticosteroid dependence and colchicine resistance remain still an unsolved issue in search of new therapies, although old...
Source: Progress in Cardiovascular Diseases - October 6, 2016 Category: Cardiology Authors: Massimo Imazio, Elena Gribaudo, Fiorenzo Gaita Tags: Invited review Source Type: research

Exercise and Hypertension: Uncovering the Mechanisms of Vascular Control
Hypertension (HTN) has recently been determined to be the number one overall risk factor of disease. With direct and indirect costs amounting to $46.4 billion in 2011 and projections of six-fold increases by 2030, the importance of low-cost nonpharmacological interventions can be appreciated. Vascular structural changes, endothelial dysfunction, and sympathetic overstimulation are major contributing factors to the pathophysiology of HTN. Exercise training (ET) for blood pressure (BP) control has been shown to be an effective and integral component of nonpharmacological interventions for BP control. (Source: Progress in Car...
Source: Progress in Cardiovascular Diseases - September 29, 2016 Category: Cardiology Authors: Ahmad Sabbahi, Ross Arena, Ahmed Elokda, Shane A. Phillips Source Type: research

New Concepts in Hypertension Management: A Population-Based Perspective
Hypertension (HTN) is the most common chronic disease in the U.S., and the standard model of office-based care delivery has yielded suboptimal outcomes, with approximately 50% of affected patients not achieving blood pressure (BP) control. Poor population-level BP control has been primarily attributed to therapeutic inertia and low patient engagement. New models of care delivery utilizing patient-generated health data, comprehensive assessment of social health determinants, computerized algorithms generating tailored interventions, frequent communication and reporting, and non-physician providers organized as an integrated...
Source: Progress in Cardiovascular Diseases - September 28, 2016 Category: Cardiology Authors: Richard V. Milani, Carl J. Lavie, Jonathan K. Wilt, Robert M. Bober, Hector O. Ventura Source Type: research

Hypertension Treatment in Blacks: Discussion of the U.S. Clinical Practice Guidelines
Blacks are especially susceptible to hypertension( HTN) and its associated organ damage leading to adverse cardiovascular, cerebrovascular and renal outcomes. Accordingly, HTN is particularly significant in contributing to the black-white racial differences in health outcomes in the US. As such, in order to address these health disparities, practical clinical practice guidelines (CPGs) on how to treat HTN, specifically in blacks, are needed. This review article is a timely addition to the literature because the most recent U.S. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - September 28, 2016 Category: Cardiology Authors: Stephen K. Williams, Joseph Ravenell, Sara Seyedali, Sam Nayef, Gbenga Ogedegbe Source Type: research

Role Of Counseling To Promote Adherence In Healthy Lifestyle Medicine: Strategies to Improve Exercise Adherence and Enhance Physical Activity
Although healthy lifestyles (HL) offer a number of health benefits, nonadherence to recommended lifestyle changes remains a frequent and difficult obstacle to realizing these benefits. Behavioral counseling can improve adherence to a HL. However, individuals' motivation for change and resistance to altering unhealthy habits must be considered when developing an effective approach to counseling. In the present article, we review psychological, behavioral, and environmental factors that may promote adherence and contribute to nonadherence. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - September 13, 2016 Category: Cardiology Authors: Gregory L. Stonerock, James A. Blumenthal Source Type: research

A Case for Less Intensive Blood Pressure Control: It Matters to Achieve Target Blood Pressure Early and Sustained Below 140/90mmHg
Although high blood pressure (BP) is the leading risk factors for cardiovascular (CV) disease, the optimal BP treatment target in order to reduce CV risk is unclear in the aftermath of the SPRINT study. The aim of this review is to assess large, randomized, and controlled trials on BP targets, as well as review selected observational analyses from other large randomized BP trials in order to evaluate the benefit of intense vs. standard BP control. None of the studies, except SPRINT, favored intense BP treatment. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - September 8, 2016 Category: Cardiology Authors: Julian E. Mariampillai, Per Anders Esk ås, Sondre Heimark, Sverre E. Kjeldsen, Krzysztof Narkiewicz, Giuseppe Mancia Source Type: research

Current Perspectives on Left Ventricular Geometry in Systemic Hypertension
Hypertension (HTN) is a global health problem and a leading risk factor for cardiovascular disease (CVD) morbidity and mortality. The hemodynamic overload from HTN causes left ventricular (LV) remodeling, which usually manifests as distinct alterations in LV geometry, such as concentric remodeling or concentric and eccentric LV hypertrophy (LVH). In addition to being a common target organ response to HTN, LV geometric abnormalities are well-known independent risk factors for CVD. Because of their prognostic implications and quantifiable nature, changes in LV geometric parameters have commonly been included as an outcome in...
Source: Progress in Cardiovascular Diseases - September 6, 2016 Category: Cardiology Authors: Ahmet Af şin Oktay, Carl J. Lavie, Richard V. Milani, Hector O. Ventura, Yvonne E. Gilliland, Sangeeta Shah, Michael E. Cash Source Type: research