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Cutaneous Manifestations of Chronic Vascular Disease
In the contemporary era of medical diagnosis via sophisticated radiographic imaging and/or comprehensive serological testing, a focused physical examination remains paramount in recognizing the cutaneous manifestations of chronic vascular disease. Recognition of the unique cutaneous signs of lymphatic and venous hypertension assists in the diagnosis as well as the staging and classification of both lymphedema and chronic venous insufficiency. Awareness of explicit dermatologic vasomotor manifestations aids not only in the identification of acrocyanosis, Raynaud phenomenon, pernio, and erythromelalgia but also mitigates con...
Source: Progress in Cardiovascular Diseases - March 10, 2018 Category: Cardiology Authors: Steven M. Dean Source Type: research

Next Generation Endovascular Therapies in Peripheral Artery Disease
Endovascular therapy (EVT) of symptomatic peripheral artery disease (PAD) offers relief of symptoms and enhanced quality of life. Advancements in technique and technology have increased the feasibility and practicality of EVT, which now represents the preferred mode of revascularization over surgical procedures in many centers across the world. In this review, we consider the future of EVT in context of a rapidly expanding population of patients with symptomatic PAD. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - March 10, 2018 Category: Cardiology Authors: Matthew C. Bunte, Mehdi H. Shishehbor Source Type: research

Peri-Procedural Management of Oral Anticoagulants in the DOAC Era
Peri-procedural management of oral anticoagulants can be complex and confusing for many providers. It involves a careful balance of a patient's thromboembolic risk and bleeding risk. For every patient chronically taking an oral anticoagulant who will be undergoing an elective procedure, a four step approach may be considered when creating a plan for the oral anticoagulant.(Writing Group M, 20161) Does the oral anticoagulant need to stop for the procedure?(Periprocedural Management of Anticoagulation Writing C, Doherty JU, Gluckman TJ, et al., 20172) If yes, when should the oral anticoagulant be stopped pre-procedure?(Douke...
Source: Progress in Cardiovascular Diseases - March 10, 2018 Category: Cardiology Authors: Geoffrey D. Barnes, Erin Mouland Source Type: research

Fibromuscular Dysplasia: Contemporary Concepts and Future Directions
Fibromuscular dyplasia (FMD) is an under-recognized non-atherosclerotic, non-inflammatory arteriopathy that occurs most commonly in middle-aged women, but may affect individuals of all age groups. FMD may result in stenosis, aneurysm, dissection, occlusion, or arterial tortuosity. Recently published data demonstrated a genetic association of FMD with a variant in the phosphatase and actin regulator 1 gene (PHACTR1), substantiating that the pathogenesis of this condition has genetic contribution. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - March 10, 2018 Category: Cardiology Authors: Nupoor Narula, Daniella Kadian-Dodov, Jeffrey W. Olin Source Type: research

Factors to Consider Regarding the Need for Inferior Vena Cava Filters
There continues to be controversy on the use of inferior vena cava (IVC) filters in patients with deep venous thrombosis, pulmonary embolism, and venous thromboembolism. In this state of the art review, the benefits and risks of IVC filters are discussed. Based on the current state of knowledge regarding the efficacy and risks of this therapy, guidelines are suggested regarding the patients who need and who do not need this expensive, risky, but potentially life-saving therapy. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - March 1, 2018 Category: Cardiology Authors: Piotr Sobieszczyk Source Type: research

Masthead
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Source: Progress in Cardiovascular Diseases - March 1, 2018 Category: Cardiology Source Type: research

Table of Contents
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Source: Progress in Cardiovascular Diseases - March 1, 2018 Category: Cardiology Source Type: research

List of Recent Issues
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Source: Progress in Cardiovascular Diseases - March 1, 2018 Category: Cardiology Source Type: research

Editorial Board
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Source: Progress in Cardiovascular Diseases - March 1, 2018 Category: Cardiology Source Type: research

Coffee for Cardioprotection and Longevity
Coffee, a complex brew containing hundreds of biologically active compounds, exerts potent effects on long-term human health. Recently, a plethora of studies have been published focusing on health outcomes associated with coffee intake. An inverse association between coffee consumption and all-cause mortality has been seen consistently in large prospective studies. Habitual coffee consumption is also associated with lower risks for cardiovascular (CV) death and a variety of adverse CV outcomes, including coronary heart disease (CHD), congestive heart failure (HF), and stroke; coffee's effects on arrhythmias and hypertensio...
Source: Progress in Cardiovascular Diseases - February 20, 2018 Category: Cardiology Authors: James H. O'Keefe, James J. DiNicolantonio, Carl J. Lavie Source Type: research

Alcohol and CV Health: Jekyll and Hyde J-Curves
A routine of light or moderate alcohol consumption ( ≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US). (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - February 17, 2018 Category: Cardiology Authors: Evan L. O'Keefe, James J. Di Nicolantonio, James H. O'Keefe, Carl J. Lavie Source Type: research

Evidence-Based Exercise Recommendations to Reduce Hepatic Fat Content in Youth- a Systematic Review and Meta-Analysis
The main purposes of this study were to elucidate the effects of supervised-exercise training (ET) interventions on hepatic fat content and on non-alcoholic fatty liver disease (NAFLD) prevalence in children and adolescents and to provide information about the optimal ET prescription (type, intensity, volume, and frequency) needed to reduce hepatic fat content in youths. Supervised-ET interventions performed in children and adolescents (6 –19 years) that provided results of exercise effects on hepatic fat content or NAFLD prevalence were included. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - February 13, 2018 Category: Cardiology Authors: Mar ía Medrano, Cristina Cadenas-Sanchez, Celia Álvarez-Bueno, Iván Cavero-Redondo, Jonatan R. Ruiz, Francisco B. Ortega, Idoia Labayen Source Type: research

Effect of High Intensity Interval Training on Cardiac Function in Children with Obesity: A Randomised Controlled Trial
High intensity interval training (HIIT) confers superior cardiovascular health benefits to moderate intensity continuous training (MICT) in adults and may be efficacious for improving diminished cardiac function in obese children. The aim of this study was to compare the effects of HIIT, MICT and nutrition advice interventions on resting left ventricular (LV) peak systolic tissue velocity (S ′) in obese children. (Source: Progress in Cardiovascular Diseases)
Source: Progress in Cardiovascular Diseases - February 13, 2018 Category: Cardiology Authors: Charlotte B. Ingul, Katrin A. Dias, Arnt E. Tjonna, Turid Follestad, Mansoureh S. Hosseini, Anita S. Timilsina, Siri M. Hollekim-Strand, Torstein B. Ro, Peter S.W. Davies, Peter A. Cain, Gary M. Leong, Jeff S. Coombes Source Type: research