Child pneumonia – focus on the Western Pacific Region
Worldwide, pneumonia is the leading cause of death in infants and young children (aged75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 15, 2016 Category: Respiratory Medicine Authors: T.K.P. Nguyen, T.H. Tran, C.L. Roberts, S.M. Graham, B.J. Marais Tags: Review Source Type: research

Exercise inducible laryngeal obstruction: diagnostics and management
Obstruction of the central airways is an important cause of exercise-induced inspiratory symptoms (EIIS) in young and otherwise healthy individuals. This is a large, heterogeneous and vastly understudied group of patients. The symptoms are too often confused with those of asthma. Laryngoscopy performed as symptoms evolve during increasing exercise is pivotal, since the larynx plays an important role in symptomatology for the majority. Abnormalities vary between patients, and laryngoscopic findings are important for correct treatment and handling. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 15, 2016 Category: Respiratory Medicine Authors: Ola Drange R øksund, John-Helge Heimdal, Hege Clemm, Maria Vollsæter, Thomas Halvorsen Source Type: research

Child pneumonia in the western pacific region
Worldwide, pneumonia is the leading cause of death in infants and young children (aged < 5 years). We provide an overview of the global pneumonia disease burden, as well as the aetiology and management practices in different parts of the world, with a specific focus on the WHO Western Pacific Region. In 2011, the Western Pacific region had an estimated 0.11 pneumonia episodes per child-year with 61,900 pneumonia-related deaths in children less than 5 years of age. The majority ( > 75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 15, 2016 Category: Respiratory Medicine Authors: T.K.P. Nguyen, T.H. Tran, C. Robert, S.M. Graham, B.J. Marais Source Type: research

Exercise inducible laryngeal obstruction: diagnostics and management
Obstruction of the central airways is an important cause of exercise-induced inspiratory symptoms (EIIS) in young and otherwise healthy individuals. This is a large, heterogeneous and vastly understudied group of patients. The symptoms are too often confused with those of asthma. Laryngoscopy performed as symptoms evolve during increasing exercise is pivotal, since the larynx plays an important role in symptomatology for the majority. Abnormalities vary between patients, and laryngoscopic findings are important for correct treatment and handling. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 15, 2016 Category: Respiratory Medicine Authors: Ola Drange Røksund, John-Helge Heimdal, Hege Clemm, Maria Vollsæter, Thomas Halvorsen Source Type: research

Child pneumonia in the western pacific region
Worldwide, pneumonia is the leading cause of death in infants and young children (aged 75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 15, 2016 Category: Respiratory Medicine Authors: T.K.P. Nguyen, T.H. Tran, C. Robert, S.M. Graham, B.J. Marais Source Type: research

Risk factors for child pneumonia - focus on the Western Pacific Region
Pneumonia is a major cause of disease and death in infants and young children (aged (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 13, 2016 Category: Respiratory Medicine Authors: T.K.P. Nguyen, T.H. Tran, C.L. Roberts, G.J. Fox, S.M. Graham, B.J. Marais Tags: Review Source Type: research

Risk factors for child pneumonia- focus on the Western Pacific Region
Pneumonia is a major cause of disease and death in infants and young children (aged < 5 years) globally, as it is in the World Health Organization Western Pacific region. A better understanding of the underlying risk factors associated with child pneumonia is important, since pragmatic primary prevention strategies are likely to achieve major reductions in pneumonia-associated morbidity and mortality in children. This review focuses on risk factors with high relevance to the Western Pacific region, including a lack of exclusive breastfeeding, cigarette smoke and air pollution exposure, malnutrition and conditions of povert...
Source: Paediatric Respiratory Reviews - July 13, 2016 Category: Respiratory Medicine Authors: TKP Nguyen, TH Tran, CL Roberts, GJ Fox, SM Graham, BJ Marais Source Type: research

Risk factors for child pneumonia- focus on the Western Pacific Region
Pneumonia is a major cause of disease and death in infants and young children (aged (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - July 13, 2016 Category: Respiratory Medicine Authors: TKP Nguyen, TH Tran, CL Roberts, GJ Fox, SM Graham, BJ Marais Source Type: research

Neutrophil Extracellular Traps in Respiratory Disease: guided anti-microbial traps or toxic webs?
Neutrophil recruitment to the airways and lungs is a major hallmark of many respiratory diseases. One of the more recently discovered unique innate immune effector mechanisms of neutrophils is the formation of neutrophil extracellular traps (NETs), consisting of an extracellular network of DNA fibers studded with nuclear and granule proteins. Although in the respiratory system NETs contribute to capture and inactivation of bacteria, fungi and viruses, there is a delicate ‘balance’ between aid and damage to the host. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 28, 2016 Category: Respiratory Medicine Authors: B. Cortjens, J.B.M. van Woensel, R.A. Bem Tags: Today's Science - Tomorrow's Medicine Source Type: research

Question 10: Could the Burden of Care with Cystic Fibrosis Impact on Educational Outcomes?
With advances in the management of cystic fibrosis (CF), affected children are living longer and reaching adulthood. This places greater emphasis on a child's ability to fulfill one of the main goals of childhood, that is, to prepare for adulthood. Despite medical advances, there's a high treatment burden required to maintain health, potentially compromising the young person's ability to achieve their full academic potential, impacting on their future career options. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 26, 2016 Category: Respiratory Medicine Authors: Anida Hanxhiu, Karen McKay, Davinder Singh-Grewal, Dominic A. Fitzgerald Tags: Cystic Fibrosis Frequently Asked Questions Source Type: research

Question 10: Could the Burden of Care with Cystic Fibrosis Impact on Educational Outcomes?
(Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 26, 2016 Category: Respiratory Medicine Authors: Anida Hanxhiu, Karen McKay, Davinder Singh-Grewal, Dominic A Fitzgerald Source Type: research

Bone health and disease in cystic fibrosis
Low bone mineral density is common in children and adults with CF. It has a multifactorial aetiology that includes direct effects of CFTR dysfunction on bone cell activity, as well as the secondary effects of CFTR dysfunction including pancreatic insufficiency (leading to malnutrition/malabsorption of fat soluble vitamins) and pulmonary infection (leading to systemic inflammation and increased bone resorption). Strategies to improve bone health in CF include optimising general CF nutritional and pulmonary care and the judicious use of bisphosphonates in selected patients. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 20, 2016 Category: Respiratory Medicine Authors: Malcolm Marquette, Charles S. Haworth Source Type: research

Cystic Fibrosis in Children and Adults
This supplement arises out of the 29th one-day meeting on cystic fibrosis (CF) organised by the Section of Paediatrics of the Royal Society of Medicine. This meeting was organised by Dr Iolo Doull and held at the Royal Society of Medicine in London on 17 November 2015. We are grateful to Actavis UK for their support. (Source: Paediatric Respiratory Reviews)
Source: Paediatric Respiratory Reviews - June 17, 2016 Category: Respiratory Medicine Authors: T.J. David Tags: Preface Source Type: research