Rib-Based Anchors for Growing Rods in the Treatment of Early Onset Scoliosis
The treatment of early onset scoliosis has evolved substantially over the years. Traditional growing rod constructs rely on spine based fixation for proximal and distal anchor sites. Hybrid growing rod constructs pair rib based proximal anchors with spinal or pelvic anchors distally. Both traditional and hybrid growing rod constructs can control spinal deformity in young patients with early onset scoliosis while preserving spinal and thoracic growth. Proximal rib fixation has many theoretical and practical advantages over spine based proximal anchors. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - September 14, 2016 Category: Orthopaedics Authors: Daniel J. Miller, Michael G. Vitale Source Type: research

Anterior Vertebral Body Stapling and Tethering
The current standard of care for skeletally immature patients with progressive scoliosis measuring> 25 ° is a thoracolumbosacral orthosis (TLSO). Recent evidence has established the efficacy of bracing in halting curve progression in patients with curves measuring 20–40°. However, issues surrounding psychosocial impact, compliance, and the efficacy of bracing in larger curves remain. In patients with significant growth remaining, anterior growth modulation surgery has been established as a unique and promising alternative. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - September 14, 2016 Category: Orthopaedics Authors: Robert J. Ames, Amer F. Samdani, Randal R. Betz Source Type: research

Hemivertebra excision - Posterior-only approach with 3-rod technique
Posterior-only hemivertebra excision (PHVE) is effective treatment for isolated hemivertebrae which cause significant local deformity. Multiple balanced hemivertebrae or global structural deformity are probably not appropriate for PHVE. PHVE works well in cervico-thoracic, thoraco-lumbar, lumbar and lumbosacral locations, with varying degrees of technical difficulty, while mid-thoracic PHVE seems less effective. Associated segmental kyphotic deformity is most easily treated, while segmental lordosis can be problematic with a posterior-only approach. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - September 14, 2016 Category: Orthopaedics Authors: John B. Emans, Michael Glotzbecker, Daniel Hedequist Source Type: research

Editorial Board
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - August 31, 2016 Category: Orthopaedics Source Type: research

Contributors
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - August 31, 2016 Category: Orthopaedics Source Type: research

Table of Contents
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - August 31, 2016 Category: Orthopaedics Source Type: research

Biologic Treatments in Intervertebral Disc Degeneration: Protein-Based and Cell-Based Therapies
Lumbar back pain is a clinical entity of global significance. Intervertebral disc degeneration (IDD) is a commonly attributed source of lumbar back pain that has a vast potential for treatment innovation. The current basis of treatments for IDD, both nonoperative and surgical, focuses largely on alleviating symptoms rather than restoring native anatomy, biology, and mechanics. Advances in the understanding of intervertebral disc (IVD) biology and IDD pathogenesis have given rise to the field of regenerative medicine including protein-based and cell-based therapies. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 26, 2016 Category: Orthopaedics Authors: Nicholas J. Vaudreuil, Nam V. Vo, Gwendolyn A. Sowa Source Type: research

Biologic Treatments in Intervertebral Disc Degeneration: Protein-based and Cell-based Therapies
Lumbar back pain is a clinical entity of global significance. Intervertebral disc degeneration (IDD) is a commonly attributed source of lumbar back pain that has a vast potential for treatment innovation. The current basis of treatments for IDD, both non-operative and surgical, focuses largely on alleviating symptoms rather than restoring native anatomy, biology, and mechanics. Advances in the understanding of intervertebral disc (IVD) biology and IDD pathogenesis have given rise to the field of regenerative medicine including protein-based and cell-based therapies. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 26, 2016 Category: Orthopaedics Authors: Nicholas J. Vaudreuil, Nam V. Vo, Gwendolyn A. Sowa Source Type: research

Cell-Mediated Pathologies in Traumatic Orthopaedic Injuries
Physical trauma is one of the most common mechanisms leading to orthopaedic injury. The trauma and associated inflammatory response initiates the process of tissue regeneration and repair, which includes the recruitment and induction of multipotential cells to participate in the process. Too much inflammation can overwhelm this response to cause scarring. Although stem cells have been extensively studied as therapy for regenerating functional tissues, concerns of ethics, availability, and ease of clinical utility call for investigation into an alternative source of multipotential cells for potential therapeutic use. (Sourc...
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Daniel W. Griffin, Youngmi Ji, Vyomesh Patel, Leon J. Nesti Source Type: research

Sexual Dimorphism in Stem Cell –Based Therapies for the Musculoskeletal System
Musculoskeletal health is one of the areas of medicine in which the differences between males and females are most striking. Differences in disease prevalence, pain sensation, drug handling, and healing responses between individuals have known biologic bases; however, the impact of sex on these biologic processes is unclear. In skeletal muscle tissues, stem cells and progenitor cells are known to persist throughout life and contribute to the ongoing process of repair and regeneration. However, currently, there is a paucity of literature that describes the sex-related differences in satellite cells and other muscle stem cel...
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Jihee Sohn, Johnny Huard Source Type: research

Cartilage Therapy and Repair in Equine Athletes
The status of articular cartilage often defines the level, progression, and subsequent prognosis of joint disease in both human and equine athletes. Although methods to diagnose equine cartilage defects have significantly improved over the past decade, articular cartilage damage and ensuing osteoarthritis remain a challenge to treat. The following 2 categories of surgical options for cartilage repair in the horse are typically considered: palliative and reparative or restorative. Palliative surgical care consists of arthroscopic debridement and lavage, whereas reparative options involve the use of marrow stimulation techni...
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Sherry A. Johnson, David D. Frisbie Source Type: research

The Current State of Stem Cell Therapies in Sports Medicine
The theoretical clinical potential of stem cells in the orthopaedic sports medicine setting is unprecedented. The application of cellular-based treatments, such as stem cells represents a fascinating and continuously evolving therapeutic approach into treating underlying pathologies. In recent years, technological advancements and innovation have shifted the mindset of clinicians from treating symptomatology to fundamentally altering the underlying disease process at the primordial molecular level. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Jeffrey M. DeLong, James P. Bradley Source Type: research

Cell and Biomimetic Scaffold-Based Approaches for Cartilage Regeneration
This article discusses tissue engineering approaches in the repair of focal cartilage defects and degenerative joint conditions. It introduces the traditionally applied methods and provides a look at newer clinical and preclinical cell-based therapies for these treatments. In addition, cutting-edge approaches, both on the cellular front and the scaffold fabrication front, are examined for potential clinical application. Finally, the article closes with a look at future perspectives and directions in studying and understanding degenerative joint diseases. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Aaron X. Sun, Piya-on Numpaisal, Riccardo Gottardi, He Shen, Guang Yang, Rocky S. Tuan Source Type: research

Cartilage Therapy & Repair in Equine Athletes
The status of articular cartilage often defines the level, progression and subsequent prognosis of joint disease in both human and equine athletes. While methods to diagnose equine cartilage defects have significantly improved over the last decade, articular cartilage damage and ensuing osteoarthritis (OA) remain a challenge to treat. Two categories of surgical options for cartilage repair in the horse are typically considered: palliative, reparative/restorative. Palliative surgical care consists of arthroscopic debridement and lavage, while reparative options involve the use of marrow stimulation techniques. (Source: Oper...
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Sherry A. Johnson, David D. Frisbie Source Type: research

Sexual Dimorphism in Stem Cell based therapies for the Musculoskeletal System
Musculoskeletal health is one of the areas of medicine in which the differences between males and females are most striking. Differences in disease prevalence, pain sensation, drug handling, and healing responses between individuals have known biologic bases; however, how these biologic processes are affected by sex is unclear. In skeletal muscle tissues, stem cells and progenitor cells are known to persist throughout life and contribute to the ongoing process of repair and regeneration. However, currently, there is a paucity of literature that describes the sex-related differences in satellite cells and other muscle stem ...
Source: Operative Techniques in Orthopaedics - June 12, 2016 Category: Orthopaedics Authors: Jihee Sohn, Johnny Huard Source Type: research