Biologic Treatments in Intervertebral Disc Degeneration: Protein-Based and Cell-Based Therapies

Lumbar back pain is a clinical entity of global significance. Intervertebral disc degeneration (IDD) is a commonly attributed source of lumbar back pain that has a vast potential for treatment innovation. The current basis of treatments for IDD, both nonoperative and surgical, focuses largely on alleviating symptoms rather than restoring native anatomy, biology, and mechanics. Advances in the understanding of intervertebral disc (IVD) biology and IDD pathogenesis have given rise to the field of regenerative medicine including protein-based and cell-based therapies.
Source: Operative Techniques in Orthopaedics - Category: Orthopaedics Authors: Source Type: research