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Editorial
In this Theme Issue Part II, the basic science foundation established in the Theme Issue Part I, “Small Molecule Biologic and Gene-Based Treatments in Sports Medicine,” is expanded to touch upon several different orthopaedic systems to cover the vast field of sports medicine and also adult reconstruction, spine, hand surgery, and orthopaedic traumatology. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 9, 2016 Category: Orthopaedics Authors: Volker Musahl, Rocky Tuan Source Type: research

Tendon-Derived Stem Cells for Rotator Cuff Repair
Rotator cuff tear is a common cause of shoulder pain and disability, and arthroscopic repair is a frequently performed procedure. To improve results and reduce failure rate of this surgery, biological solutions to enhance tendon repair are being investigated. Mesenchymal stem cells contribute in creating a suitable microenvironment for tissue repair, and therefore therapeutic use of tendon tissue-specific stem cells in clinical practice is one of the most promising challenges in regenerative medicine approaches to rotator cuff repair. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 9, 2016 Category: Orthopaedics Authors: Pietro Randelli, Davide Cucchi, Federico Cabitza, Riccardo Compagnoni, Alessandra Menon Source Type: research

Tendon-Derived Stem: Cells for Rotator Cuff Repair
Rotator cuff tear is a common cause of shoulder pain and disability, and arthroscopic repair is a frequently performed procedure. To improve results and reduce failure rate of this surgery, biological solutions to enhance tendon repair are being investigated. Mesenchymal stem cells contribute in creating a suitable microenvironment for tissue repair, and therefore therapeutic use of tendon tissue-specific stem cells in clinical practice is one of the most promising challenges in regenerative medicine approaches to rotator cuff repair. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 9, 2016 Category: Orthopaedics Authors: Pietro Randelli, Davide Cucchi, Federico Cabitza, Riccardo Compagnoni, Alessandra Menon Source Type: research

Editorial PRP Theme Issue Part II
In this Theme Issue Part II, the basic science foundation established in the Theme Issue Part I, “Small Molecule Biologic and Gene Based Treatments in Sports Medicine”, is expanded to touch upon several different orthopaedic systems to cover the vast field of sports medicine and also adult reconstruction, spine, hand surgery, and orthopaedic traumatology. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 9, 2016 Category: Orthopaedics Authors: Volker Musahl, Rocky Tuan Source Type: research

Tendon-Derived Stem Cells for Rotator Cuff Repair
Rotator cuff tears are a common cause of shoulder pain and disability and arthroscopic repair is a frequently performed procedure. To improve results and reduce failure rate of this surgery, biological solutions to enhance tendon repair are being investigated. Mesenchymal stem cells contribute in creating a suitable microenvironment for tissue repair and therefore therapeutic use of tendon tissue specific stem cells in clinical practice is one of the most promising challenges in regenerative medicine approaches to rotator cuff repair. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - June 9, 2016 Category: Orthopaedics Authors: Pietro Randelli, Davide Cucchi, Federico Cabitza, Riccardo Compagnoni, Alessandra Menon Source Type: research

Editorial Board
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Table of Contents
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Contributors
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Editorial Board
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Table of Contents
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Contributors
(Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - May 31, 2016 Category: Orthopaedics Source Type: research

Clinical Outcomes of Biologic Treatment for Chronic Tendinopathy
Biological interventions, such as ultrasound guided platelet rich plasma (PRP) injections, are a second line treatment worth considering for recalcitrant tendinopathy, but efficacy and effectiveness have not been established yet. The use of PRP has been most commonly studied in lateral epicondylitis, with nine randomized controlled trials and seven prospective controlled studies in the medical literature. Corticosteroid injection was used as the comparator in six studies, autologous blood in three, and local anesthetic agents in two studies. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - March 4, 2016 Category: Orthopaedics Authors: Isabel Andia, Nicola Maffulli Source Type: research

Application of Tscs and Prp to Treat Tendon Injuries
Tendon injuries like tendinopathy are a serious healthcare problem in the United States. However, current treatments for tendon injuries are largely palliative. Biologics treatments, including tendon stem/progenitor cells (TSCs) and platelet rich plasma (PRP) hold great potential to effectively treat tendon injuries. TSCs are tendon specific stem cells and have the ability to differentiate into tenocytes, the resident tendon cells responsible for tendon homeostasis and tendon repair in case of an injury. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - March 4, 2016 Category: Orthopaedics Authors: James H-C. Wang, Xavier Nirmala Source Type: research

Clinical Outcomes of Biologic Treatment for Chronic Tendinopathy
Biological interventions, such as ultrasound-guided platelet-rich plasma (PRP) injections, are a second-line treatment worth considering for recalcitrant tendinopathy, but efficacy and effectiveness have not been established yet. The use of PRP has been most commonly studied in lateral epicondylitis, with 9 randomized controlled trials and 7 prospective controlled studies in the medical literature. Corticosteroid injection was used as the comparator in 6 studies, autologous blood in 3, and local anesthetic agents in 2 studies. (Source: Operative Techniques in Orthopaedics)
Source: Operative Techniques in Orthopaedics - March 3, 2016 Category: Orthopaedics Authors: Isabel Andia, Nicola Maffulli Source Type: research